VITAL THERAPIES INC

CUSIP: 92847R104 Class: COM

TWO SIGMA SECURITIES, LLC's Holding History (CIK: 0001450144)

Note: Option positions (PUT/CALL) are excluded.

Q4 2018
Shares 11,710 Value ($000) $2 Avg Close — Range —
Q3 2018
Shares 55,722 Value ($000) $15 Avg Close — Range —