VITAL THERAPIES INC

CUSIP: 92847R104 Class: COM

TWO SIGMA ADVISERS, LP's Holding History (CIK: 0001478735)

Note: Option positions (PUT/CALL) are excluded.

Q1 2019
Shares 91,200 Value ($000) $18 Avg Close — Range —
Q4 2018
Shares 86,100 Value ($000) $16 Avg Close — Range —
Q3 2018
Shares 14,000 Value ($000) $4 Avg Close — Range —