VYNE THERAPEUTICS INC

CUSIP: 92941V100 Class: COM NEW

TWO SIGMA ADVISERS, LP's Holding History (CIK: 0001478735)

Note: Option positions (PUT/CALL) are excluded.

Q4 2020
Shares 469,200 Value ($000) $741 Avg Close — Range —
Q3 2020
Shares 207,400 Value ($000) $344 Avg Close — Range —