VYNE THERAPEUTICS INC

CUSIP: 92941V209 Class: Stock

TWO SIGMA SECURITIES, LLC's Holding History (CIK: 0001450144)

Note: Option positions (PUT/CALL) are excluded.

Q4 2022
Shares 18,901 Value ($000) $3 Avg Close — Range —
Q2 2022
Shares 127,844 Value ($000) $50 Avg Close — Range —
Q4 2021
Shares 47,475 Value ($000) $48 Avg Close — Range —