VYNE THERAPEUTICS INC

CUSIP: 92941V209 Class: Stock

TWO SIGMA ADVISERS, LP's Holding History (CIK: 0001478735)

Note: Option positions (PUT/CALL) are excluded.

Q2 2021
Shares 44,400 Value ($000) $156 Avg Close — Range —
Q1 2021
Shares 228,750 Value ($000) $1,566 Avg Close — Range —