VYNE THERAPEUTICS INC

Ticker: VYNE CUSIP: 92941V308 Class: COM

ACADIAN ASSET MANAGEMENT LLC's Holding History (CIK: 0000916542)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 638,492 Value ($000) $0 Avg Close $0.40 Range $0.32 - $0.75

Q3 2025

Shares 446,414 Value ($000) $0 Avg Close $0.65 Range $0.28 - $1.96

Q2 2025

Shares 22,418 Value ($000) $0 Avg Close $1.30 Range $0.85 - $1.99

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	638,492	$0	$0.40	$0.32 - $0.75
Q3 2025	446,414	$0	$0.65	$0.28 - $1.96
Q2 2025	22,418	$0	$1.30	$0.85 - $1.99