XILIO THERAPEUTICS INC

Ticker: XLO CUSIP: 98422T100 Class: COM

TWO SIGMA INVESTMENTS, LP's Holding History (CIK: 0001179392)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 62,032 Value ($000) $40 Avg Close $0.75 Range $0.63 - $0.90

Q3 2025

Shares 87,790 Value ($000) $74 Avg Close $0.72 Range $0.61 - $0.91

Q2 2025

Shares 78,032 Value ($000) $53 Avg Close $0.75 Range $0.62 - $1.18

Q1 2025

Shares 84,068 Value ($000) $61 Avg Close $0.90 Range $0.63 - $1.70

Q4 2024

Shares 10,824 Value ($000) $10 Avg Close $0.98 Range $0.71 - $1.54

Q3 2024

Shares 10,389 Value ($000) $8 Avg Close $0.88 Range $0.68 - $1.03

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	62,032	$40	$0.75	$0.63 - $0.90
Q3 2025	87,790	$74	$0.72	$0.61 - $0.91
Q2 2025	78,032	$53	$0.75	$0.62 - $1.18
Q1 2025	84,068	$61	$0.90	$0.63 - $1.70
Q4 2024	10,824	$10	$0.98	$0.71 - $1.54
Q3 2024	10,389	$8	$0.88	$0.68 - $1.03