YIELD10 BIOSCIENCE INC

CUSIP: 98585K862 Class: COM

TWO SIGMA INVESTMENTS, LP's Holding History (CIK: 0001179392)

Note: Option positions (PUT/CALL) are excluded.

Q2 2021
Shares 19,733 Value ($000) $168 Avg Close — Range —
Q1 2021
Shares 31,411 Value ($000) $394 Avg Close — Range —
Q4 2020
Shares 21,789 Value ($000) $126 Avg Close — Range —