ZALICUS INC

CUSIP: 98887C204 Class: Common Stock

D. E. Shaw & Co., Inc.'s Holding History (CIK: 0001009207)

Note: Option positions (PUT/CALL) are excluded.

Q2 2014
Shares 308,322 Value ($000) $376 Avg Close — Range —
Q1 2014
Shares 330,522 Value ($000) $403 Avg Close — Range —
Q4 2013
Shares 323,544 Value ($000) $359 Avg Close — Range —