ZYMEWORKS INC

CUSIP: 98985W102 Class: COM

TWO SIGMA ADVISERS, LP's Holding History (CIK: 0001478735)

Note: Option positions (PUT/CALL) are excluded.

Q2 2022
Shares 71,600 Value ($000) $379 Avg Close — Range —
Q1 2022
Shares 304,300 Value ($000) $1,993 Avg Close — Range —
Q4 2021
Shares 35,000 Value ($000) $574 Avg Close — Range —
Q3 2021
Shares 95,400 Value ($000) $2,770 Avg Close — Range —
Q2 2021
Shares 138,500 Value ($000) $4,805 Avg Close — Range —
Q1 2021
Shares 323,900 Value ($000) $10,229 Avg Close — Range —
Q4 2020
Shares 351,900 Value ($000) $16,631 Avg Close — Range —
Q3 2020
Shares 388,100 Value ($000) $18,078 Avg Close — Range —
Q2 2020
Shares 534,300 Value ($000) $19,272 Avg Close — Range —
Q1 2020
Shares 474,200 Value ($000) $16,820 Avg Close — Range —
Q4 2019
Shares 286,500 Value ($000) $13,024 Avg Close — Range —
Q3 2019
Shares 34,300 Value ($000) $851 Avg Close — Range —
Q2 2019
Shares 20,800 Value ($000) $458 Avg Close — Range —