ZYNERBA PHARMACEUTICALS INC

CUSIP: 98986X109 Class: COM

TWO SIGMA INVESTMENTS, LP's Holding History (CIK: 0001179392)

Note: Option positions (PUT/CALL) are excluded.

Q2 2023
Shares 70,163 Value ($000) $23 Avg Close — Range —
Q1 2023
Shares 70,170 Value ($000) $30 Avg Close — Range —
Q4 2022
Shares 71,070 Value ($000) $38 Avg Close — Range —
Q3 2022
Shares 122,662 Value ($000) $90 Avg Close — Range —
Q1 2022
Shares 107,747 Value ($000) $221 Avg Close — Range —
Q4 2021
Shares 26,096 Value ($000) $75 Avg Close — Range —
Q3 2021
Shares 190,430 Value ($000) $807 Avg Close — Range —
Q2 2021
Shares 65,476 Value ($000) $346 Avg Close — Range —
Q1 2021
Shares 63,746 Value ($000) $296 Avg Close — Range —
Q4 2019
Shares 69,563 Value ($000) $420 Avg Close — Range —
Q4 2018
Shares 40,447 Value ($000) $120 Avg Close — Range —
Q1 2016
Shares 14,851 Value ($000) $140 Avg Close — Range —