ZYNERBA PHARMACEUTICALS INC

CUSIP: 98986X109 Class: COM

TWO SIGMA ADVISERS, LP's Holding History (CIK: 0001478735)

Note: Option positions (PUT/CALL) are excluded.

Q2 2023
Shares 124,000 Value ($000) $40 Avg Close — Range —
Q1 2023
Shares 144,900 Value ($000) $62 Avg Close — Range —
Q4 2022
Shares 186,000 Value ($000) $99 Avg Close — Range —
Q3 2022
Shares 197,600 Value ($000) $145 Avg Close — Range —
Q2 2022
Shares 196,100 Value ($000) $224 Avg Close — Range —
Q1 2022
Shares 141,600 Value ($000) $290 Avg Close — Range —
Q4 2021
Shares 107,500 Value ($000) $310 Avg Close — Range —
Q3 2021
Shares 175,300 Value ($000) $743 Avg Close — Range —
Q2 2021
Shares 128,600 Value ($000) $680 Avg Close — Range —
Q1 2021
Shares 167,900 Value ($000) $781 Avg Close — Range —