HORIZON PHARMA PLC

CUSIP: G4617B105 Class: SHS

FIRST MANHATTAN CO. LLC.'s Holding History (CIK: 0000728083)

Note: Option positions (PUT/CALL) are excluded.

Q3 2016
Shares 16,297 Value ($000) $295 Avg Close — Range —
Q2 2016
Shares 16,297 Value ($000) $268 Avg Close — Range —
Q1 2016
Shares 20,208 Value ($000) $334 Avg Close — Range —
Q4 2015
Shares 20,208 Value ($000) $437 Avg Close — Range —
Q3 2015
Shares 20,208 Value ($000) $400 Avg Close — Range —