HORIZON PHARMA PLC

CUSIP: G4617B105 Class: SHS

MANUFACTURERS LIFE INSURANCE COMPANY, THE's Holding History (CIK: 0000928047)

Note: Option positions (PUT/CALL) are excluded.

Q1 2019
Shares 116,634 Value ($000) $3,082 Avg Close — Range —
Q4 2018
Shares 112,976 Value ($000) $2,208 Avg Close — Range —
Q3 2018
Shares 106,880 Value ($000) $2,093 Avg Close — Range —
Q2 2018
Shares 121,984 Value ($000) $2,020 Avg Close — Range —
Q1 2018
Shares 121,124 Value ($000) $1,720 Avg Close — Range —
Q4 2017
Shares 124,396 Value ($000) $1,816 Avg Close — Range —
Q3 2017
Shares 123,978 Value ($000) $1,572 Avg Close — Range —
Q2 2017
Shares 125,933 Value ($000) $1,495 Avg Close — Range —
Q1 2017
Shares 124,554 Value ($000) $1,841 Avg Close — Range —
Q4 2016
Shares 109,632 Value ($000) $1,774 Avg Close — Range —
Q3 2016
Shares 109,203 Value ($000) $1,980 Avg Close — Range —
Q2 2016
Shares 108,847 Value ($000) $1,793 Avg Close — Range —
Q1 2016
Shares 4,494 Value ($000) $72 Avg Close — Range —
Q4 2015
Shares 4,138 Value ($000) $90 Avg Close — Range —
Q3 2015
Shares 4,138 Value ($000) $82 Avg Close — Range —
Q2 2015
Shares 4,170 Value ($000) $145 Avg Close — Range —
Q1 2015
Shares 44,056 Value ($000) $1,144 Avg Close — Range —
Q4 2014
Shares 42,567 Value ($000) $549 Avg Close — Range —
Q3 2014
Shares 42,941 Value ($000) $527 Avg Close — Range —