HORIZON PHARMA PLC

CUSIP: G4617B105 Class: SHS

Artal Group S.A.'s Holding History (CIK: 0001053906)

Note: Option positions (PUT/CALL) are excluded.

Q3 2017
Shares 500,000 Value ($000) $6,340 Avg Close — Range —
Q2 2017
Shares 760,000 Value ($000) $9,021 Avg Close — Range —
Q1 2017
Shares 800,000 Value ($000) $11,824 Avg Close — Range —
Q4 2016
Shares 500,000 Value ($000) $8,090 Avg Close — Range —
Q3 2016
Shares 350,000 Value ($000) $6,346 Avg Close — Range —
Q2 2016
Shares 350,000 Value ($000) $5,765 Avg Close — Range —