NABRIVA THERAPEUTICS PLC

CUSIP: G63637105 Class: SHS

TWO SIGMA INVESTMENTS, LP's Holding History (CIK: 0001179392)

Note: Option positions (PUT/CALL) are excluded.

Q4 2019
Shares 171,364 Value ($000) $226 Avg Close — Range —
Q3 2019
Shares 101,462 Value ($000) $203 Avg Close — Range —
Q1 2019
Shares 125,475 Value ($000) $306 Avg Close — Range —
Q4 2018
Shares 57,869 Value ($000) $84 Avg Close — Range —
Q3 2018
Shares 123,013 Value ($000) $332 Avg Close — Range —