PROTHENA CORP PLC

Ticker: PRTA CUSIP: G72800108 Class: Common Stock

CULLEN/FROST BANKERS, INC.'s Holding History (CIK: 0000039263)

Note: Option positions (PUT/CALL) are excluded.

Q4 2019

Shares 100 Value ($000) $2 Avg Close $10.72 Range $7.40 - $17.63

Q3 2019

Shares 100 Value ($000) $1 Avg Close $8.88 Range $6.71 - $10.70

Q2 2019

Shares 100 Value ($000) $1 Avg Close $10.27 Range $8.67 - $12.54

Q1 2019

Shares 100 Value ($000) $1 Avg Close $12.49 Range $9.97 - $14.77

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2019	100	$2	$10.72	$7.40 - $17.63
Q3 2019	100	$1	$8.88	$6.71 - $10.70
Q2 2019	100	$1	$10.27	$8.67 - $12.54
Q1 2019	100	$1	$12.49	$9.97 - $14.77