PROTHENA CORP PLC

Ticker: PRTA CUSIP: G72800108 Class: Common Stock

TWO SIGMA INVESTMENTS, LP's Holding History (CIK: 0001179392)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025
Shares 670,138 Value ($000) $6,400 Avg Close $10.18 Range $9.07 - $11.69
Q3 2025
Shares 426,605 Value ($000) $4,164 Avg Close $7.69 Range $5.96 - $9.85
Q2 2025
Shares 201,450 Value ($000) $1,223 Avg Close $7.50 Range $4.32 - $12.45
Q1 2025
Shares 16,033 Value ($000) $198 Avg Close $14.14 Range $11.78 - $16.66
Q4 2024
Shares 38,394 Value ($000) $532 Avg Close $15.77 Range $11.70 - $18.88
Q3 2024
Shares 10,507 Value ($000) $176 Avg Close $21.50 Range $15.52 - $25.42
Q2 2024
Shares 71,559 Value ($000) $1,477 Avg Close $21.64 Range $18.69 - $26.36
Q3 2023
Shares 136,203 Value ($000) $6,572 Avg Close $59.41 Range $45.22 - $73.14
Q2 2023
Shares 162,733 Value ($000) $11,111 Avg Close $64.50 Range $47.45 - $79.65
Q1 2023
Shares 365,539 Value ($000) $17,718 Avg Close $52.83 Range $45.06 - $60.82
Q4 2022
Shares 203,435 Value ($000) $12,257 Avg Close $58.56 Range $50.89 - $66.47
Q3 2022
Shares 135,685 Value ($000) $8,227 Avg Close $31.61 Range $25.02 - $64.00
Q2 2022
Shares 230,427 Value ($000) $6,256 Avg Close $29.25 Range $21.06 - $40.31
Q1 2022
Shares 261,291 Value ($000) $9,555 Avg Close $36.05 Range $29.53 - $49.77
Q4 2021
Shares 301,454 Value ($000) $14,892 Avg Close $55.45 Range $40.50 - $74.32
Q3 2021
Shares 321,166 Value ($000) $22,877 Avg Close $62.11 Range $45.09 - $79.75
Q2 2021
Shares 336,990 Value ($000) $17,325 Avg Close $31.20 Range $21.30 - $59.74
Q1 2021
Shares 296,378 Value ($000) $7,445 Avg Close $18.81 Range $10.72 - $28.66
Q4 2020
Shares 50,581 Value ($000) $607 Avg Close $11.83 Range $9.86 - $14.14
Q3 2020
Shares 99,811 Value ($000) $997 Avg Close $12.03 Range $9.67 - $13.78
Q2 2020
Shares 114,324 Value ($000) $1,196 Avg Close $11.11 Range $9.25 - $12.98
Q1 2020
Shares 82,330 Value ($000) $881 Avg Close $12.11 Range $7.10 - $16.05
Q4 2019
Shares 147,062 Value ($000) $2,328 Avg Close $10.72 Range $7.40 - $17.63
Q3 2019
Shares 121,043 Value ($000) $949 Avg Close $8.88 Range $6.71 - $10.70
Q2 2019
Shares 367,523 Value ($000) $3,885 Avg Close $10.27 Range $8.67 - $12.54
Q1 2019
Shares 401,724 Value ($000) $4,873 Avg Close $12.49 Range $9.97 - $14.77
Q4 2018
Shares 363,576 Value ($000) $3,745 Avg Close $11.89 Range $8.63 - $13.83
Q3 2018
Shares 286,407 Value ($000) $3,746 Avg Close $14.44 Range $12.23 - $15.91
Q4 2017
Shares 12,594 Value ($000) $472 Avg Close $50.91 Range $34.85 - $64.96
Q4 2015
Shares 25,726 Value ($000) $1,752 Avg Close $60.32 Range $40.47 - $76.42
Q3 2015
Shares 4,622 Value ($000) $210 Avg Close $58.24 Range $42.20 - $70.52
Q2 2015
Shares 111,544 Value ($000) $5,875 Avg Close $39.47 Range $30.14 - $55.97
Q2 2014
Shares 78,479 Value ($000) $1,770 Avg Close $25.01 Range $18.52 - $41.33
Q1 2014
Shares 65,783 Value ($000) $2,520 Avg Close $32.24 Range $24.42 - $49.24
Q4 2013
Shares 17,790 Value ($000) $472 Avg Close $25.08 Range $18.93 - $30.55