PROTHENA CORP PLC

Ticker: PRTA CUSIP: G72800108 Class: Common Stock

TANG CAPITAL MANAGEMENT LLC's Holding History (CIK: 0001232621)

Note: Option positions (PUT/CALL) are excluded.

Q3 2020

Shares 178,688 Value ($000) $1,785 Avg Close $12.03 Range $9.67 - $13.78

Q2 2020

Shares 273,823 Value ($000) $2,864 Avg Close $11.11 Range $9.25 - $12.98

Q1 2020

Shares 423,823 Value ($000) $4,535 Avg Close $12.11 Range $7.10 - $16.05

Q4 2019

Shares 423,823 Value ($000) $6,709 Avg Close $10.72 Range $7.40 - $17.63

Q3 2019

Shares 423,823 Value ($000) $3,323 Avg Close $8.88 Range $6.71 - $10.70

Q2 2019

Shares 323,823 Value ($000) $3,423 Avg Close $10.27 Range $8.67 - $12.54

Q1 2019

Shares 323,823 Value ($000) $3,928 Avg Close $12.49 Range $9.97 - $14.77

Q4 2018

Shares 47,610 Value ($000) $490 Avg Close $11.89 Range $8.63 - $13.83

Period	Shares	Value ($000)	Average Close	Price Range
Q3 2020	178,688	$1,785	$12.03	$9.67 - $13.78
Q2 2020	273,823	$2,864	$11.11	$9.25 - $12.98
Q1 2020	423,823	$4,535	$12.11	$7.10 - $16.05
Q4 2019	423,823	$6,709	$10.72	$7.40 - $17.63
Q3 2019	423,823	$3,323	$8.88	$6.71 - $10.70
Q2 2019	323,823	$3,423	$10.27	$8.67 - $12.54
Q1 2019	323,823	$3,928	$12.49	$9.97 - $14.77
Q4 2018	47,610	$490	$11.89	$8.63 - $13.83