PROTHENA CORP PLC

Ticker: PRTA CUSIP: G72800108 Class: Common Stock

CLOUGH CAPITAL PARTNERS L P's Holding History (CIK: 0001276144)

Note: Option positions (PUT/CALL) are excluded.

Q4 2015

Shares 38,400 Value ($000) $2,615 Avg Close $60.32 Range $40.47 - $76.42

Q3 2015

Shares 65,400 Value ($000) $2,965 Avg Close $58.24 Range $42.20 - $70.52

Q2 2015

Shares 69,400 Value ($000) $3,655 Avg Close $39.47 Range $30.14 - $55.97

Q1 2015

Shares 145,200 Value ($000) $5,538 Avg Close $25.65 Range $18.76 - $45.00

Q4 2014

Shares 133,000 Value ($000) $2,761 Avg Close $20.87 Range $17.00 - $24.67

Q3 2014

Shares 101,500 Value ($000) $2,249 Avg Close $21.20 Range $16.71 - $24.31

Q2 2014

Shares 105,800 Value ($000) $2,386 Avg Close $25.01 Range $18.52 - $41.33

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2015	38,400	$2,615	$60.32	$40.47 - $76.42
Q3 2015	65,400	$2,965	$58.24	$42.20 - $70.52
Q2 2015	69,400	$3,655	$39.47	$30.14 - $55.97
Q1 2015	145,200	$5,538	$25.65	$18.76 - $45.00
Q4 2014	133,000	$2,761	$20.87	$17.00 - $24.67
Q3 2014	101,500	$2,249	$21.20	$16.71 - $24.31
Q2 2014	105,800	$2,386	$25.01	$18.52 - $41.33