PROTHENA CORP PLC

Ticker: PRTA CUSIP: G72800108 Class: Common Stock

RA CAPITAL MANAGEMENT, L.P.'s Holding History (CIK: 0001346824)

Note: Option positions (PUT/CALL) are excluded.

Q1 2014

Shares 1,554,918 Value ($000) $59,569 Avg Close $32.24 Range $24.42 - $49.24

Q4 2013

Shares 1,641,167 Value ($000) $43,524 Avg Close $25.08 Range $18.93 - $30.55

Q3 2013

Shares 1,646,399 Value ($000) $33,307 Avg Close $17.69 Range $12.14 - $22.48

Q2 2013

Shares 497,807 Value ($000) $6,427 Avg Close $9.30 Range $6.49 - $14.00

Period	Shares	Value ($000)	Average Close	Price Range
Q1 2014	1,554,918	$59,569	$32.24	$24.42 - $49.24
Q4 2013	1,641,167	$43,524	$25.08	$18.93 - $30.55
Q3 2013	1,646,399	$33,307	$17.69	$12.14 - $22.48
Q2 2013	497,807	$6,427	$9.30	$6.49 - $14.00