PROTHENA CORP PLC

Ticker: PRTA CUSIP: G72800108 Class: Common Stock

Connor, Clark & Lunn Investment Management Ltd.'s Holding History (CIK: 0001596800)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 125,890 Value ($000) $1,202 Avg Close $10.18 Range $9.07 - $11.69

Q2 2025

Shares 18,896 Value ($000) $115 Avg Close $7.50 Range $4.32 - $12.45

Q1 2025

Shares 91,482 Value ($000) $1,132 Avg Close $14.14 Range $11.78 - $16.66

Q4 2024

Shares 91,840 Value ($000) $1,272 Avg Close $15.77 Range $11.70 - $18.88

Q3 2024

Shares 122,492 Value ($000) $2,049 Avg Close $21.50 Range $15.52 - $25.42

Q2 2024

Shares 112,826 Value ($000) $2,329 Avg Close $21.64 Range $18.69 - $26.36

Q1 2024

Shares 131,905 Value ($000) $3,267 Avg Close $29.75 Range $24.25 - $41.55

Q4 2023

Shares 155,942 Value ($000) $5,667 Avg Close $38.49 Range $28.51 - $55.89

Q3 2023

Shares 127,775 Value ($000) $6,165 Avg Close $59.41 Range $45.22 - $73.14

Q2 2023

Shares 110,136 Value ($000) $7,520 Avg Close $64.50 Range $47.45 - $79.65

Q1 2023

Shares 89,424 Value ($000) $4,334 Avg Close $52.83 Range $45.06 - $60.82

Q4 2022

Shares 60,432 Value ($000) $3,641 Avg Close $58.56 Range $50.89 - $66.47

Q3 2022

Shares 27,556 Value ($000) $1,671 Avg Close $31.61 Range $25.02 - $64.00

Q2 2022

Shares 16,030 Value ($000) $435 Avg Close $29.25 Range $21.06 - $40.31

Q3 2021

Shares 6,690 Value ($000) $477 Avg Close $62.11 Range $45.09 - $79.75

Q1 2020

Shares 26,225 Value ($000) $281 Avg Close $12.11 Range $7.10 - $16.05

Q4 2019

Shares 20,125 Value ($000) $319 Avg Close $10.72 Range $7.40 - $17.63

Q3 2019

Shares 23,925 Value ($000) $188 Avg Close $8.88 Range $6.71 - $10.70

Q2 2019

Shares 19,350 Value ($000) $205 Avg Close $10.27 Range $8.67 - $12.54

Q3 2015

Shares 4,500 Value ($000) $204 Avg Close $58.24 Range $42.20 - $70.52

Q2 2015

Shares 25,500 Value ($000) $1,343 Avg Close $39.47 Range $30.14 - $55.97

Q1 2015

Shares 38,100 Value ($000) $1,453 Avg Close $25.65 Range $18.76 - $45.00

Q4 2014

Shares 28,100 Value ($000) $583 Avg Close $20.87 Range $17.00 - $24.67

Q3 2014

Shares 9,100 Value ($000) $202 Avg Close $21.20 Range $16.71 - $24.31

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	125,890	$1,202	$10.18	$9.07 - $11.69
Q2 2025	18,896	$115	$7.50	$4.32 - $12.45
Q1 2025	91,482	$1,132	$14.14	$11.78 - $16.66
Q4 2024	91,840	$1,272	$15.77	$11.70 - $18.88
Q3 2024	122,492	$2,049	$21.50	$15.52 - $25.42
Q2 2024	112,826	$2,329	$21.64	$18.69 - $26.36
Q1 2024	131,905	$3,267	$29.75	$24.25 - $41.55
Q4 2023	155,942	$5,667	$38.49	$28.51 - $55.89
Q3 2023	127,775	$6,165	$59.41	$45.22 - $73.14
Q2 2023	110,136	$7,520	$64.50	$47.45 - $79.65
Q1 2023	89,424	$4,334	$52.83	$45.06 - $60.82
Q4 2022	60,432	$3,641	$58.56	$50.89 - $66.47
Q3 2022	27,556	$1,671	$31.61	$25.02 - $64.00
Q2 2022	16,030	$435	$29.25	$21.06 - $40.31
Q3 2021	6,690	$477	$62.11	$45.09 - $79.75
Q1 2020	26,225	$281	$12.11	$7.10 - $16.05
Q4 2019	20,125	$319	$10.72	$7.40 - $17.63
Q3 2019	23,925	$188	$8.88	$6.71 - $10.70
Q2 2019	19,350	$205	$10.27	$8.67 - $12.54
Q3 2015	4,500	$204	$58.24	$42.20 - $70.52
Q2 2015	25,500	$1,343	$39.47	$30.14 - $55.97
Q1 2015	38,100	$1,453	$25.65	$18.76 - $45.00
Q4 2014	28,100	$583	$20.87	$17.00 - $24.67
Q3 2014	9,100	$202	$21.20	$16.71 - $24.31