PROTHENA CORP PLC

Ticker: PRTA CUSIP: G72800108 Class: Common Stock

Avidity Partners Management LP's Holding History (CIK: 0001791827)

Note: Option positions (PUT/CALL) are excluded.

Q3 2023

Shares 382,305 Value ($000) $18,446 Avg Close $59.41 Range $45.22 - $73.14

Q2 2023

Shares 535,000 Value ($000) $36,530 Avg Close $64.50 Range $47.45 - $79.65

Q1 2023

Shares 1,068,200 Value ($000) $51,776 Avg Close $52.83 Range $45.06 - $60.82

Q4 2022

Shares 2,953,000 Value ($000) $177,918 Avg Close $58.56 Range $50.89 - $66.47

Q3 2022

Shares 1,967,000 Value ($000) $119,259 Avg Close $31.61 Range $25.02 - $64.00

Q2 2021

Shares 182,000 Value ($000) $9,357 Avg Close $31.20 Range $21.30 - $59.74

Period	Shares	Value ($000)	Average Close	Price Range
Q3 2023	382,305	$18,446	$59.41	$45.22 - $73.14
Q2 2023	535,000	$36,530	$64.50	$47.45 - $79.65
Q1 2023	1,068,200	$51,776	$52.83	$45.06 - $60.82
Q4 2022	2,953,000	$177,918	$58.56	$50.89 - $66.47
Q3 2022	1,967,000	$119,259	$31.61	$25.02 - $64.00
Q2 2021	182,000	$9,357	$31.20	$21.30 - $59.74