PROTHENA CORP PLC

Ticker: PRTA CUSIP: G72800108 Class: Common Stock

Paradigm Biocapital Advisors LP's Holding History (CIK: 0001855655)

Note: Option positions (PUT/CALL) are excluded.

Q4 2022

Shares 75,000 Value ($000) $4,519 Avg Close $58.56 Range $50.89 - $66.47

Q3 2022

Shares 235,826 Value ($000) $14,298 Avg Close $31.61 Range $25.02 - $64.00

Q1 2022

Shares 267,946 Value ($000) $9,799 Avg Close $36.05 Range $29.53 - $49.77

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2022	75,000	$4,519	$58.56	$50.89 - $66.47
Q3 2022	235,826	$14,298	$31.61	$25.02 - $64.00
Q1 2022	267,946	$9,799	$36.05	$29.53 - $49.77