STRONGBRIDGE BIOPHARMA PLC

CUSIP: G85347105 Class: SHS USD

TWO SIGMA ADVISERS, LP's Holding History (CIK: 0001478735)

Note: Option positions (PUT/CALL) are excluded.

Q3 2021
Shares 150,600 Value ($000) $307 Avg Close — Range —
Q2 2021
Shares 252,600 Value ($000) $750 Avg Close — Range —
Q1 2021
Shares 434,600 Value ($000) $1,199 Avg Close — Range —
Q4 2020
Shares 496,800 Value ($000) $1,207 Avg Close — Range —
Q3 2020
Shares 336,500 Value ($000) $707 Avg Close — Range —
Q2 2020
Shares 88,800 Value ($000) $336 Avg Close — Range —
Q1 2020
Shares 29,800 Value ($000) $56 Avg Close — Range —
Q2 2018
Shares 12,600 Value ($000) $76 Avg Close — Range —