TIZIANA LIFE SCIENCES LTD

Ticker: TLSA CUSIP: G88912103 Class: COMMON SHARES

JANE STREET GROUP, LLC's Holding History (CIK: 0001595888)

Note: Option positions (PUT/CALL) are excluded.

Q3 2025

Shares 17,987 Value ($000) $39 Avg Close $1.85 Range $1.43 - $2.60

Q2 2025

Shares 24,964 Value ($000) $39 Avg Close $1.34 Range $0.73 - $1.81

Q1 2025

Shares 167,542 Value ($000) $181 Avg Close $0.98 Range $0.63 - $1.91

Q4 2024

Shares 15,684 Value ($000) $11 Avg Close $0.93 Range $0.63 - $1.27

Q2 2023

Shares 12,971 Value ($000) $9 Avg Close $0.85 Range $0.65 - $1.39

Q3 2022

Shares 10,139 Value ($000) $8 Avg Close $0.75 Range $0.55 - $0.91

Q4 2021

Shares 49,439 Value ($000) $47 Avg Close $1.33 Range $0.85 - $1.70

Period	Shares	Value ($000)	Average Close	Price Range
Q3 2025	17,987	$39	$1.85	$1.43 - $2.60
Q2 2025	24,964	$39	$1.34	$0.73 - $1.81
Q1 2025	167,542	$181	$0.98	$0.63 - $1.91
Q4 2024	15,684	$11	$0.93	$0.63 - $1.27
Q2 2023	12,971	$9	$0.85	$0.65 - $1.39
Q3 2022	10,139	$8	$0.75	$0.55 - $0.91
Q4 2021	49,439	$47	$1.33	$0.85 - $1.70