ALCOBRA LTD

CUSIP: M2239P109 Class: SHS

BAKER BROS. ADVISORS LP's Holding History (CIK: 0001263508)

Note: Option positions (PUT/CALL) are excluded.

Q4 2016
Shares 2,336,359 Value ($000) $4,906 Avg Close — Range —
Q3 2016
Shares 2,336,359 Value ($000) $5,771 Avg Close — Range —
Q2 2016
Shares 2,336,359 Value ($000) $10,490 Avg Close — Range —
Q1 2016
Shares 2,336,359 Value ($000) $8,855 Avg Close — Range —
Q4 2015
Shares 2,336,359 Value ($000) $14,672 Avg Close — Range —
Q3 2015
Shares 1,639,871 Value ($000) $9,905 Avg Close — Range —
Q2 2015
Shares 1,789,871 Value ($000) $11,706 Avg Close — Range —
Q1 2015
Shares 1,789,871 Value ($000) $10,077 Avg Close — Range —
Q4 2014
Shares 289,871 Value ($000) $1,081 Avg Close — Range —