PAINREFORM LTD

CUSIP: M77798102 Class: SHS

TWO SIGMA SECURITIES, LLC's Holding History (CIK: 0001450144)

Note: Option positions (PUT/CALL) are excluded.

Q1 2023
Shares 14,188 Value ($000) $10 Avg Close — Range —
Q4 2022
Shares 18,897 Value ($000) $8 Avg Close — Range —