Ticker	Issuer	Shares	Value	%	Share Price	Est. Cost/Share	Unrealized @ Report Date	Class	CUSIP
ALKT	ALKAMI TECHNOLOGY INC	600,284	$10.88M	1.7%	$18.12	$18.12	—	COM	01644J108
CELC	CELCUITY INC	64,110	$6.707M	1.1%	$104.62	$104.62	—	COM	15102K100
RARE	ULTRAGENYX PHARMACEUTICAL IN	100,000	$3.339M	0.5%	$33.39	$23.36	—	CALL	90400D108
SLN	SILENCE THERAPEUTICS PLC	300,000	$3.294M	0.5%	$10.98	$6.66	—	CALL	82686Q101
CUE	CUE BIOPHARMA INC	93,819	$2.961M	0.5%	$31.56	$31.56	—	COM	22978P205
ACRS	ACLARIS THERAPEUTICS INC	400,000	$2.116M	0.3%	$5.29	$5.29	—	COM	00461U105
AGIO	AGIOS PHARMACEUTICALS INC	50,000	$1.855M	0.3%	$37.11	$35.39	—	CALL	00847X104
GLUE	MONTE ROSA THERAPEUTICS INC	56,052	$1.356M	0.2%	$24.20	$24.20	—	COM	61225M102
TENX	TENAX THERAPEUTICS INC	75,100	$1.093M	0.2%	$14.55	—	—	CALL	88032L605
AMLX	AMYLYX PHARMACEUTICALS INC	8,500	$153K	0.0%	$17.96	$7.12	—	CALL	03237H101

Increased Positions (16)

PATH UIPATH INC 53.0%

Value $336M (+20.2%) Shares 30,950,000 (+22.8%) Share Price $10.87 Est. Cost/Share $13.61 Unrealized @ Report Date —

DFTX DEFINIUM THERAPEUTICS INC 2.1%

Value $13.5M (+257.2%) Shares 286,990 (+43.5%) Share Price $47.04 Est. Cost/Share $25.61 Unrealized @ Report Date —

RLAY RELAY THERAPEUTICS INC 1.7%

Value $10.67M (+490.7%) Shares 570,311 (+214.1%) Share Price $18.71 Est. Cost/Share $15.40 Unrealized @ Report Date —

MBX MBX BIOSCIENCES INC 1.8%

Value $11.24M (+158.7%) Shares 203,543 (+39.9%) Share Price $55.20 Est. Cost/Share $25.55 Unrealized @ Report Date —

SLN SILENCE THERAPEUTICS PLC 1.3%

Value $8.392M (+152.7%) Shares 764,256 (+21.3%) Share Price $10.98 Est. Cost/Share $6.66 Unrealized @ Report Date —

IONS IONIS PHARMACEUTICALS INC 1.2%

Value $7.705M (+145.7%) Shares 97,173 (+132.7%) Share Price $79.29 Est. Cost/Share $80.37 Unrealized @ Report Date —

IMVT IMMUNOVANT INC 1.6%

Value $9.861M (+81.7%) Shares 255,934 (+17.1%) Share Price $38.53 Est. Cost/Share $23.59 Unrealized @ Report Date —

ALKS ALKERMES PLC 1.6%

Value $9.954M (+76.2%) Shares 189,979 (+18.9%) Share Price $52.40 Est. Cost/Share $33.05 Unrealized @ Report Date —

HRMY HARMONY BIOSCIENCES HLDGS IN 1.2%

Value $7.32M (+119.0%) Shares 201,036 (+68.5%) Share Price $36.41 Est. Cost/Share $34.82 Unrealized @ Report Date —

PHVS PHARVARIS N V 1.6%

Value $10.22M (+63.3%) Shares 295,627 (+33.4%) Share Price $34.58 Est. Cost/Share $22.16 Unrealized @ Report Date —

DYN DYNE THERAPEUTICS INC 1.2%

Value $7.921M (+69.3%) Shares 356,657 (+38.2%) Share Price $22.21 Est. Cost/Share $14.92 Unrealized @ Report Date —

ARWR ARROWHEAD PHARMACEUTICALS IN 1.7%

Value $10.64M (+33.4%) Shares 130,484 (+2.6%) Share Price $81.51 Est. Cost/Share $36.76 Unrealized @ Report Date —

KPTI KARYOPHARM THERAPEUTICS INC 0.4%

Value $2.445M (+778.1%) Shares 250,300 (+400.6%) Share Price $9.77 Est. Cost/Share $7.62 Unrealized @ Report Date —

AGIO AGIOS PHARMACEUTICALS INC 1.2%

Value $7.629M (+36.8%) Shares 205,579 (+24.7%) Share Price $37.11 Est. Cost/Share $35.39 Unrealized @ Report Date —

ACAD ACADIA PHARMACEUTICALS INC 0.7%

Value $4.247M (+31.9%) Shares 167,875 (+16.1%) Share Price $25.30 Est. Cost/Share $25.22 Unrealized @ Report Date —

TECX TECTONIC THERAPEUTIC INC 0.3%

Value $1.599M (+37.6%) Shares 46,516 (+23.8%) Share Price $34.38 Est. Cost/Share $23.65 Unrealized @ Report Date —

Ticker	Issuer	Shares	Value	%	Share Price	Est. Cost/Share	Unrealized @ Report Date	Class	CUSIP
PATH	UIPATH INC	30,950,000 (+22.8%)	$336M (+20.2%)	53.0%	$10.87	$13.61	—	CL A	90364P105
DFTX	DEFINIUM THERAPEUTICS INC	286,990 (+43.5%)	$13.5M (+257.2%)	2.1%	$47.04	$25.61	—	COM SHS	24477V105
RLAY	RELAY THERAPEUTICS INC	570,311 (+214.1%)	$10.67M (+490.7%)	1.7%	$18.71	$15.40	—	COM	75943R102
MBX	MBX BIOSCIENCES INC	203,543 (+39.9%)	$11.24M (+158.7%)	1.8%	$55.20	$25.55	—	COM	55287L101
SLN	SILENCE THERAPEUTICS PLC	764,256 (+21.3%)	$8.392M (+152.7%)	1.3%	$10.98	$6.66	—	ADS	82686Q101
IONS	IONIS PHARMACEUTICALS INC	97,173 (+132.7%)	$7.705M (+145.7%)	1.2%	$79.29	$80.37	—	COM	462222100
IMVT	IMMUNOVANT INC	255,934 (+17.1%)	$9.861M (+81.7%)	1.6%	$38.53	$23.59	—	COM	45258J102
ALKS	ALKERMES PLC	189,979 (+18.9%)	$9.954M (+76.2%)	1.6%	$52.40	$33.05	—	SHS	G01767105
HRMY	HARMONY BIOSCIENCES HLDGS IN	201,036 (+68.5%)	$7.32M (+119.0%)	1.2%	$36.41	$34.82	—	COM	413197104
PHVS	PHARVARIS N V	295,627 (+33.4%)	$10.22M (+63.3%)	1.6%	$34.58	$22.16	—	COM	N69605108
DYN	DYNE THERAPEUTICS INC	356,657 (+38.2%)	$7.921M (+69.3%)	1.2%	$22.21	$14.92	—	COM	26818M108
ARWR	ARROWHEAD PHARMACEUTICALS IN	130,484 (+2.6%)	$10.64M (+33.4%)	1.7%	$81.51	$36.76	—	COM	04280A100
KPTI	KARYOPHARM THERAPEUTICS INC	250,300 (+400.6%)	$2.445M (+778.1%)	0.4%	$9.77	$7.62	—	CALL	48576U205
AGIO	AGIOS PHARMACEUTICALS INC	205,579 (+24.7%)	$7.629M (+36.8%)	1.2%	$37.11	$35.39	—	COM	00847X104
ACAD	ACADIA PHARMACEUTICALS INC	167,875 (+16.1%)	$4.247M (+31.9%)	0.7%	$25.30	$25.22	—	COM	004225108
TECX	TECTONIC THERAPEUTIC INC	46,516 (+23.8%)	$1.599M (+37.6%)	0.3%	$34.38	$23.65	—	COM	878972108

Exited Positions (7)

PRAX PRAXIS PRECISION MEDICINES I 0.8%

Value $5.14M Shares 15,952 Share Price $322.19 Est. Cost/Share $186.22 Unrealized @ Report Date —

SLNO SOLENO THERAPEUTICS INC 0.5%

Value $3.419M Shares 102,125 Share Price $33.48 Est. Cost/Share $41.63 Unrealized @ Report Date —

AXSM AXSOME THERAPEUTICS INC. 0.5%

Value $3.39M Shares 20,059 Share Price $169.02 Est. Cost/Share $96.47 Unrealized @ Report Date —

MPLT MAPLIGHT THERAPEUTICS INC 0.4%

Value $2.279M Shares 112,115 Share Price $20.33 Est. Cost/Share $16.75 Unrealized @ Report Date —

AARD AARDVARK THERAPEUTICS INC 0.2%

Value $1.194M Shares 316,621 Share Price $3.77 Est. Cost/Share $13.57 Unrealized @ Report Date —

RARE ULTRAGENYX PHARMACEUTICAL IN 0.1%

Value $827K Shares 39,473 Share Price $20.95 Est. Cost/Share $23.36 Unrealized @ Report Date —

KPTI KARYOPHARM THERAPEUTICS INC 0.0%

Value $295K Shares 52,984 Share Price $5.57 Est. Cost/Share $7.62 Unrealized @ Report Date —

Ticker	Issuer	Shares	Value	%	Share Price	Est. Cost/Share	Unrealized @ Report Date	Class	CUSIP
PRAX	PRAXIS PRECISION MEDICINES I	15,952	$5.14M	0.8%	$322.19	$186.22	—	—	74006W207
SLNO	SOLENO THERAPEUTICS INC	102,125	$3.419M	0.5%	$33.48	$41.63	—	—	834203309
AXSM	AXSOME THERAPEUTICS INC.	20,059	$3.39M	0.5%	$169.02	$96.47	—	—	05464T104
MPLT	MAPLIGHT THERAPEUTICS INC	112,115	$2.279M	0.4%	$20.33	$16.75	—	—	56565P103
AARD	AARDVARK THERAPEUTICS INC	316,621	$1.194M	0.2%	$3.77	$13.57	—	—	002942100
RARE	ULTRAGENYX PHARMACEUTICAL IN	39,473	$827K	0.1%	$20.95	$23.36	—	—	90400D108
KPTI	KARYOPHARM THERAPEUTICS INC	52,984	$295K	0.0%	$5.57	$7.62	—	—	48576U205

Decreased Positions (5)

WBD WARNER BROS DISCOVERY INC 1.0%

Value $6.665M (-73.7%) Shares 250,000 (-72.9%) Share Price $26.66 Est. Cost/Share $28.24 Unrealized @ Report Date —

NKTR NEKTAR THERAPEUTICS 1.0%

Value $6.073M (-18.1%) Shares 86,996 (-15.6%) Share Price $69.81 Est. Cost/Share $53.46 Unrealized @ Report Date —

AMLX AMYLYX PHARMACEUTICALS INC 0.8%

Value $5.351M (+21.1%) Shares 297,926 (-6.3%) Share Price $17.96 Est. Cost/Share $7.12 Unrealized @ Report Date —

CLDX CELLDEX THERAPEUTICS INC NEW 1.7%

Value $10.81M (+9.1%) Shares 290,441 (-7.0%) Share Price $37.21 Est. Cost/Share $24.91 Unrealized @ Report Date —

ANNX ANNEXON INC 1.1%

Value $7.094M (-0.9%) Shares 1,242,455 (-3.9%) Share Price $5.71 Est. Cost/Share $4.39 Unrealized @ Report Date —

Ticker	Issuer	Shares	Value	%	Share Price	Est. Cost/Share	Unrealized @ Report Date	Class	CUSIP
WBD	WARNER BROS DISCOVERY INC	250,000 (-72.9%)	$6.665M (-73.7%)	1.0%	$26.66	$28.24	—	COM SER A	934423104
NKTR	NEKTAR THERAPEUTICS	86,996 (-15.6%)	$6.073M (-18.1%)	1.0%	$69.81	$53.46	—	COM NEW	640268306
AMLX	AMYLYX PHARMACEUTICALS INC	297,926 (-6.3%)	$5.351M (+21.1%)	0.8%	$17.96	$7.12	—	COM	03237H101
CLDX	CELLDEX THERAPEUTICS INC NEW	290,441 (-7.0%)	$10.81M (+9.1%)	1.7%	$37.21	$24.91	—	COM NEW	15117B202
ANNX	ANNEXON INC	1,242,455 (-3.9%)	$7.094M (-0.9%)	1.1%	$5.71	$4.39	—	COM	03589W102

Unchanged Positions (8)

KGEI KOLIBRI GLOBAL ENERGY INC 5.3%

Value $33.85M Shares 6,834,504 Share Price $4.95 Est. Cost/Share $4.16 Unrealized @ Report Date —

WK WORKIVA INC 1.9%

Value $12.13M Shares 250,000 Share Price $48.51 Est. Cost/Share $71.19 Unrealized @ Report Date —

AXSM AXSOME THERAPEUTICS INC. 1.3%

Value $8.567M Shares 35,000 Share Price $244.77 Est. Cost/Share $96.47 Unrealized @ Report Date —

KRYS KRYSTAL BIOTECH INC 1.2%

Value $7.31M Shares 19,668 Share Price $371.67 Est. Cost/Share $220.15 Unrealized @ Report Date —

AUTL AUTOLUS THERAPEUTICS LTD 2.4%

Value $15.2M Shares 9,500,000 Share Price $1.60 Est. Cost/Share $4.56 Unrealized @ Report Date —

CXM SPRINKLR INC 1.8%

Value $11.35M Shares 2,200,000 Share Price $5.16 Est. Cost/Share $11.64 Unrealized @ Report Date —

LYFT LYFT INC 2.3%

Value $14.61M Shares 1,000,000 Share Price $14.61 Est. Cost/Share $17.70 Unrealized @ Report Date —

SNOW SNOWFLAKE INC 0.4%

Value $2.545M Shares 10,000 Share Price $254.50 Est. Cost/Share $209.17 Unrealized @ Report Date —

Ticker	Issuer	Shares	Value	%	Share Price	Est. Cost/Share	Unrealized @ Report Date	Class	CUSIP
KGEI	KOLIBRI GLOBAL ENERGY INC	6,834,504	$33.85M	5.3%	$4.95	$4.16	—	COM NEW	50043K406
WK	WORKIVA INC	250,000	$12.13M	1.9%	$48.51	$71.19	—	COM CL A	98139A105
AXSM	AXSOME THERAPEUTICS INC.	35,000	$8.567M	1.3%	$244.77	$96.47	—	CALL	05464T104
KRYS	KRYSTAL BIOTECH INC	19,668	$7.31M	1.2%	$371.67	$220.15	—	COM	501147102
AUTL	AUTOLUS THERAPEUTICS LTD	9,500,000	$15.2M	2.4%	$1.60	$4.56	—	SPON ADS	05280R100
CXM	SPRINKLR INC	2,200,000	$11.35M	1.8%	$5.16	$11.64	—	CL A	85208T107
LYFT	LYFT INC	1,000,000	$14.61M	2.3%	$14.61	$17.70	—	CL A COM	55087P104
SNOW	SNOWFLAKE INC	10,000	$2.545M	0.4%	$254.50	$209.17	—	COM SHS	833445109