ARCH Venture Management, LLC Diversified Active

Location: Chicago, IL

CIK: 0001274403 · Show all filings

Period: Q2 2025 (← Previous) (Next →)

Filing Date: Aug 14, 2025

Total Value: $299M (100.0% shares, 0.0% debt)

Holdings (11)

BEAM BEAM THERAPEUTICS INC. 25.8%

Value $77.23M Shares 4,540,132 Est. Cost $24.56 Unrealized -29.1%

VIR VIR BIOTECHNOLOGY INC. 21.8%

Value $65.1M Shares 12,916,663 Est. Cost $5.36 Unrealized 0.0%

MAZE MAZE THERAPEUTICS INC. 16.9%

Value $50.59M Shares 4,120,053 Est. Cost $12.04 Unrealized -13.6%

RAPP RAPPORT THERAPEUTICS INC. 14.2%

Value $42.43M Shares 3,728,738 Est. Cost $23.15 Unrealized -54.2%

— VERVE THERAPEUTICS INC. 7.5%

Value $22.56M Shares 2,008,809 Est. Cost $36.87 Unrealized —

LYEL LYELL IMMUNOPHARMA INC. 5.4%

Value $16.11M Shares 1,820,634 Est. Cost $9.11 Unrealized 0.0%

ERAS ERASCA INC. 4.7%

Value $14.1M Shares 11,055,554 Est. Cost $17.12 Unrealized -92.2%

GOSS GOSSAMER BIO INC. 3.3%

Value $9.909M Shares 8,055,916 Est. Cost $1.15 Unrealized -5.4%

QTTB Q32 BIO INC. 0.2%

Value $478K Shares 320,482 Est. Cost $13.78 Unrealized -87.6%

— UNITY BIOTECHNOLOGY INC. 0.1%

Value $386K Shares 1,004,817 Est. Cost $0.40 Unrealized —

CERO CERO THERAPEUTICS HOLDINGS INC. 0.1%

Value $216K Shares 22,389 Est. Cost $12.44 Unrealized 0.0%

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
BEAM	BEAM THERAPEUTICS INC.	4,540,132	$77.23M	25.8%	$24.56	-29.1%	COM	07373V105
VIR	VIR BIOTECHNOLOGY INC.	12,916,663	$65.1M	21.8%	$5.36	0.0%	COM	92764N102
MAZE	MAZE THERAPEUTICS INC.	4,120,053	$50.59M	16.9%	$12.04	-13.6%	COM	578784100
RAPP	RAPPORT THERAPEUTICS INC.	3,728,738	$42.43M	14.2%	$23.15	-54.2%	COM	75383L102
—	VERVE THERAPEUTICS INC.	2,008,809	$22.56M	7.5%	$36.87	—	COM	92539P101
LYEL	LYELL IMMUNOPHARMA INC.	1,820,634	$16.11M	5.4%	$9.11	0.0%	COM NEW	55083R203
ERAS	ERASCA INC.	11,055,554	$14.1M	4.7%	$17.12	-92.2%	COM	29479A108
GOSS	GOSSAMER BIO INC.	8,055,916	$9.909M	3.3%	$1.15	-5.4%	COM	38341P102
QTTB	Q32 BIO INC.	320,482	$478K	0.2%	$13.78	-87.6%	COM	746964105
—	UNITY BIOTECHNOLOGY INC.	1,004,817	$386K	0.1%	$0.40	—	COM NEW	91381U200
CERO	CERO THERAPEUTICS HOLDINGS INC.	22,389	$216K	0.1%	$12.44	0.0%	COM	71902K402