ARCH Venture Management, LLC Diversified Active

Location: Chicago, IL

CIK: 0001274403 · Show all filings

Period: Q4 2025 (← Previous) (Next →)

Filing Date: Feb 17, 2026

Total Value: $652M (100.0% shares, 0.0% debt)

Holdings (9)

MAZE MAZE THERAPEUTICS INC. 26.2%

Value $171M Shares 4,120,053 Est. Cost $12.04 Unrealized +185.5%

BEAM BEAM THERAPEUTICS INC. 19.3%

Value $126M Shares 4,540,132 Est. Cost $24.56 Unrealized +3.9%

RAPP RAPPORT THERAPEUTICS INC. 17.4%

Value $113M Shares 3,728,738 Est. Cost $23.15 Unrealized +19.5%

LYEL LYELL IMMUNOPHARMA INC. 13.0%

Value $84.92M Shares 2,759,072 Est. Cost $9.90 Unrealized +126.1%

VIR VIR BIOTECHNOLOGY INC. 12.0%

Value $77.89M Shares 12,916,663 Est. Cost $5.36 Unrealized +11.1%

ERAS ERASCA INC. 6.3%

Value $41.13M Shares 11,055,554 Est. Cost $17.12 Unrealized -83.6%

GOSS GOSSAMER BIO INC. 3.8%

Value $24.97M Shares 8,055,916 Est. Cost $1.15 Unrealized +147.6%

TXG 10X GENOMICS INC. 1.8%

Value $12.03M Shares 737,539 Est. Cost $15.11 Unrealized 0.0%

QTTB Q32 BIO INC. 0.2%

Value $1.064M Shares 320,482 Est. Cost $13.78 Unrealized -79.5%

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
MAZE	MAZE THERAPEUTICS INC.	4,120,053	$171M	26.2%	$12.04	+185.5%	COM	578784100
BEAM	BEAM THERAPEUTICS INC.	4,540,132	$126M	19.3%	$24.56	+3.9%	COM	07373V105
RAPP	RAPPORT THERAPEUTICS INC.	3,728,738	$113M	17.4%	$23.15	+19.5%	COM	75383L102
LYEL	LYELL IMMUNOPHARMA INC.	2,759,072	$84.92M	13.0%	$9.90	+126.1%	COM NEW	55083R203
VIR	VIR BIOTECHNOLOGY INC.	12,916,663	$77.89M	12.0%	$5.36	+11.1%	COM	92764N102
ERAS	ERASCA INC.	11,055,554	$41.13M	6.3%	$17.12	-83.6%	COM	29479A108
GOSS	GOSSAMER BIO INC.	8,055,916	$24.97M	3.8%	$1.15	+147.6%	COM	38341P102
TXG	10X GENOMICS INC.	737,539	$12.03M	1.8%	$15.11	0.0%	CL A COM	88025U109
QTTB	Q32 BIO INC.	320,482	$1.064M	0.2%	$13.78	-79.5%	COM	746964105