Location: Menlo Park, CA
CIK: 0001631134 · Show all filings
Period: Q3 2023 (← Previous) (Next →)
Filing Date: Nov 14, 2023
Total Value: $1.585B (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Share Price | Est. Cost/Share | Unrealized @ Report Date | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|---|
| — | Karuna Therapeutics Inc | 1,381,149 | $234M | 14.7% | $169.09 | $32.21 | — | COM | 48576A100 |
| NTRA | Natera Inc | 3,100,560 | $137M | 8.7% | $44.25 * | $9.81 | +420.0% | COM | 632307104 |
| AZN | AstraZeneca PLC | 1,362,836 | $92.29M | 5.8% | $67.72 | $71.57 | — | SPONSORED ADR | 046353108 |
| MRK | Merck & Co Inc | 728,404 | $74.99M | 4.7% | $102.95 * | $89.36 | +11.7% | COM | 58933Y105 |
| ASND | Ascendis Pharma A/S | 754,032 | $70.61M | 4.5% | $93.64 | $92.54 | — | SPONSORED ADR | 04351P101 |
| — | RayzeBio Inc | 2,419,528 | $53.71M | 3.4% | $22.20 | $22.20 | — | COM | 75525N107 |
| DXCM | Dexcom Inc | 550,197 | $51.33M | 3.2% | $93.30 * | $109.05 | +3.4% | COM | 252131107 |
| — | Aerovate Therapeutics Inc | 3,758,686 | $51.01M | 3.2% | $13.57 | $22.83 | — | COM | 008064107 |
| ISRG | Intuitive Surgical Inc | 173,277 | $50.65M | 3.2% | $292.29 * | $260.77 | +19.8% | COM | 46120E602 |
| VERA | Vera Therapeutics Inc | 3,467,156 | $47.53M | 3.0% | $13.71 * | $15.35 | +11.7% | CL A | 92337R101 |
| ELAN | Elanco Animal Health Inc | 3,610,024 | $40.58M | 2.6% | $11.24 * | $11.61 | 0.0% | COM | 28414H103 |
| IWM | IShares TR | 225,000 | $39.77M | 2.5% | $176.74 | — | — | Put | 464287655 |
| ARGX | argenx SE | 78,186 | $38.44M | 2.4% | $491.63 | $439.60 | — | SPONSORED ADR | 04016X101 |
| IMTX | Immatics NV | 3,251,509 | $37.65M | 2.4% | $11.58 * | $9.86 | +21.1% | SHS | N44445109 |
| SNY | Sanofi | 695,375 | $37.3M | 2.4% | $53.64 | $53.64 | — | SPONSORED ADR | 80105N105 |
| KVUE | Kenvue Inc | 1,802,084 | $36.19M | 2.3% | $20.08 * | $21.04 | 0.0% | COM | 49177J102 |
| IDXX | IDEXX Laboratories Inc | 77,881 | $34.06M | 2.1% | $437.27 * | $481.01 | +3.7% | COM | 45168D104 |
| — | ImmunoGen Inc | 2,045,202 | $32.46M | 2.0% | $15.87 | $11.75 | — | COM | 45253H101 |
| CYTK | Cytokinetics Inc | 1,060,164 | $31.23M | 2.0% | $29.46 * | $36.92 | -9.8% | COM | 23282W605 |
| IDYA | IDEAYA Biosciences Inc | 1,037,187 | $27.98M | 1.8% | $26.98 * | $18.98 | +33.6% | COM | 45166A102 |
| ZNTL | Zentalis Pharmaceuticals Inc | 1,211,641 | $24.31M | 1.5% | $20.06 * | $23.96 | +5.9% | COM | 98943L107 |
| SPY | SPDR S&P 500 ETF Trust | 50,000 | $21.37M | 1.3% | $427.48 | — | — | Put | 78462F103 |
| EXEL | Exelixis Inc | 912,600 | $19.94M | 1.3% | $21.85 * | $18.67 | +12.0% | Put | 30161Q104 |
| EXEL | Exelixis Inc | 830,764 | $18.15M | 1.1% | $21.85 * | $18.67 | +12.0% | COM | 30161Q104 |
| — | Inozyme Pharma Inc | 4,280,308 | $17.98M | 1.1% | $4.20 | $14.88 | — | COM | 45790W108 |
| — | Invesco QQQ TR | 50,000 | $17.91M | 1.1% | $358.27 | $358.27 | — | UNIT SER 1 | 46090E953 |
| MLTX | MoonLake Immunotherapeutics | 292,805 | $16.69M | 1.1% | $57.00 * | $55.20 | 0.0% | CLASS A ORD | 61559X104 |
| — | Shockwave Med Inc | 81,373 | $16.2M | 1.0% | $199.10 | $199.10 | — | COM | Shockwave |
| — | Agenus Inc | 13,364,748 | $15.1M | 1.0% | $1.13 | $1.36 | — | COM | 00847G705 |
| ALKS | Alkermes PLC | 537,464 | $15.05M | 0.9% | $28.01 * | $29.32 | 0.0% | SHS | G01767105 |
| CYTK | Cytokinetics Inc | 500,000 | $14.73M | 0.9% | $29.46 * | $36.92 | -9.8% | Put | 23282W605 |
| SNDX | Syndax Pharmaceuticals Inc | 941,817 | $13.68M | 0.9% | $14.52 * | $21.35 | -11.4% | COM | 87164F105 |
| — | Inhibrx Inc | 743,294 | $13.64M | 0.9% | $18.35 | $23.93 | — | COM | 45720L107 |
| — | Y-mAbs Therapeutics Inc | 2,194,278 | $11.96M | 0.8% | $5.45 | $26.75 | — | COM | 984241109 |
| CLDX | Celldex Therapeutics Inc | 424,259 | $11.68M | 0.7% | $27.52 * | $36.85 | -14.9% | COM | 15117B202 |
| GPCR | Structure Therapeutics Inc | 202,119 | $10.19M | 0.6% | $50.42 | $50.42 | — | SPONSORED ADS | 86366E106 |
| CRSP | CRISPR Therapeutics AG | 200,000 | $9.078M | 0.6% | $45.39 | — | — | Put | H17182108 |
| SNDX | Syndax Pharmaceuticals Inc | 600,000 | $8.712M | 0.5% | $14.52 * | $21.35 | -11.4% | Call | 87164F105 |
| REPL | Replimune Group Inc | 503,844 | $8.621M | 0.5% | $17.11 * | $19.57 | +0.4% | COM | 76029N106 |
| — | Marinus Pharmaceuticals Inc | 985,606 | $7.934M | 0.5% | $8.05 | $6.93 | — | COM | 56854Q200 |
| GERN | Geron Corp | 3,702,546 | $7.849M | 0.5% | $2.12 * | $2.59 | +5.0% | COM | 374163103 |
| SNDX | Syndax Pharmaceuticals Inc | 450,000 | $6.534M | 0.4% | $14.52 * | $21.35 | -11.4% | Put | 87164F105 |
| SRPT | Sarepta Therapeutics Inc | 51,100 | $6.194M | 0.4% | $121.22 | — | — | Call | 803607100 |
| DYN | Dyne Therapeutics Inc | 685,133 | $6.139M | 0.4% | $8.96 * | $11.43 | -5.8% | COM | 26818M108 |
| AXSM | Axsome Therapeutics Inc | 80,368 | $5.617M | 0.4% | $69.89 * | $68.33 | +9.4% | COM | 05464T104 |
| CLDX | Celldex Therapeutics Inc | 200,000 | $5.504M | 0.3% | $27.52 * | $36.85 | -14.9% | Put | 15117B202 |
| IMVT | Immunovant Inc | 139,885 | $5.37M | 0.3% | $38.39 * | $22.60 | 0.0% | COM | 45258J102 |
| REPL | Replimune Group Inc | 313,100 | $5.357M | 0.3% | $17.11 * | $19.57 | +0.4% | Put | 76029N106 |
| REPL | Replimune Group Inc | 250,000 | $4.277M | 0.3% | $17.11 * | $19.57 | +0.4% | Call | 76029N106 |
| — | Nextcure Inc | 2,671,856 | $3.447M | 0.2% | $1.29 | $10.01 | — | COM | 65343E108 |
| — | Nucana PLC | 5,599,999 | $3.416M | 0.2% | $0.61 | $9.47 | — | SPONSORED ADR | 67022C106 |
| — | Bolt Biotherapeutics Inc | 2,754,437 | $2.865M | 0.2% | $1.04 | $32.91 | — | COM | 097702104 |
| — | Marinus Pharmaceuticals Inc | 320,600 | $2.581M | 0.2% | $8.05 | $6.93 | — | Call | 56854Q200 |
| — | Agenus Inc | 1,600,000 | $1.808M | 0.1% | $1.13 | $1.36 | — | Call | 00847G705 |
| — | Nucana PLC | 2,400,000 | $1.464M | 0.1% | $0.61 | $4.99 | — | COMMON SHARES | GB00BYWYV |
| — | Immatics NV | 318,896 | $1.129M | 0.1% | $3.54 | $3.54 | — | *W EXP 07/01/2025 | N44445117 |
| SYK | Stryker Corporation | 3,279 | $896K | 0.1% | $273.27 * | $280.01 | 0.0% | COM | 863667101 |
| PDSB | PDS Biotechnology Corp | 142,635 | $720K | 0.0% | $5.05 * | $8.36 | -34.5% | COM | 70465T107 |
| SVRA | Savara Inc | 157,908 | $597K | 0.0% | $3.78 * | $2.82 | +26.2% | COM | 805111101 |
| GRTX | Galera Therapeutics Inc | 3,083,712 | $540K | 0.0% | $0.18 * | $12.19 | -89.8% | COM | 36338D108 |
| — | Ikena Oncology Inc | 115,712 | $501K | 0.0% | $4.33 | $4.33 | — | COM | 45175G108 |
| — | Fusion Pharmaceuticals Inc | 117,099 | $304K | 0.0% | $2.60 | $6.28 | — | COM | 36118A100 |
| MIRM | Mirum Pharmaceuticals Inc | 9,089 | $287K | 0.0% | $31.60 * | $26.59 | +3.0% | COM | 604749101 |
| — | CymaBay Therapeutics Inc | 11,040 | $165K | 0.0% | $14.91 | — | — | Put | 23257D103 |
| — | Spruce Biosciences Inc | 58,029 | $131K | 0.0% | $2.26 | $2.15 | — | COM | 85209E109 |
| SYBX | Synlogic Inc | 38,331 | $108K | 0.0% | $2.81 * | $6.79 | 0.0% | COM | 87166L209 |