EcoR1 Capital, LLC Quant / Systematic

Location: San Francisco, CA

CIK: 0001587114 · Show all filings

Period: Q4 2015 (← Previous) (Next →)

Filing Date: Feb 16, 2016

Total Value: $318M (93.2% shares, 6.8% debt)

Holdings (31)

— FIBROGEN INC 11.6%

Value $37.07M Shares 1,216,473 Est. Cost $24.72 Unrealized —

— FIVE PRIME THERAPEUTICS INC 9.4%

Value $29.84M Shares 719,000 Est. Cost $36.09 Unrealized —

— JAZZ PHARMACEUTICALS 8.4%

Value $26.59M Shares 189,200 Est. Cost — Unrealized —

— RETROPHIN INC 7.4%

Value $23.62M Shares 1,224,384 Est. Cost $21.12 Unrealized —

— ARRAY BIOPHARMA INC 6.8%

Value $21.63M Shares 22,534 Est. Cost $0.96 Unrealized —

KURA KURA ONCOLOGY INC 6.5%

Value $20.58M Shares 2,450,000 Est. Cost $10.42 Unrealized 0.0%

— ASSEMBLY BIOSCIENCES INC 4.9%

Value $15.76M Shares 2,098,302 Est. Cost $9.53 Unrealized —

CYTK CYTOKINETICS INC 4.7%

Value $14.84M Shares 1,418,700 Est. Cost $9.81 Unrealized 0.0%

— VALEANT PHARMACEUTICALS INTL 4.0%

Value $12.86M Shares 126,500 Est. Cost — Unrealized —

COLL COLLEGIUM PHARMACEUTICAL INC 4.0%

Value $12.79M Shares 465,118 Est. Cost $17.29 Unrealized +21.8%

— EPIZYME INC 3.5%

Value $11.2M Shares 698,900 Est. Cost $19.11 Unrealized —

GLPG GALAPAGOS 3.3%

Value $10.52M Shares 167,361 Est. Cost $62.88 Unrealized —

— KITE PHARMA INC 3.2%

Value $10.23M Shares 166,000 Est. Cost $57.67 Unrealized —

— FLEX PHARMA INC 3.1%

Value $9.899M Shares 795,088 Est. Cost $19.13 Unrealized —

IRWD IRONWOOD PHARMACEUTICALS 3.0%

Value $9.522M Shares 821,531 Est. Cost $9.66 Unrealized 0.0%

— NABRIVA THERAPEUTICS AG 2.5%

Value $7.931M Shares 838,680 Est. Cost $9.50 Unrealized —

— ATYR PHARMA INC 2.4%

Value $7.77M Shares 790,462 Est. Cost $18.52 Unrealized —

— KINDRED BIOSCIENCES INC 1.5%

Value $4.871M Shares 1,432,765 Est. Cost $7.10 Unrealized —

— RETROPHIN INC 1.5%

Value $4.709M Shares 244,100 Est. Cost — Unrealized —

— CELLADON CORP 1.3%

Value $4.179M Shares 2,843,170 Est. Cost $1.26 Unrealized —

— OVASCIENCE INC 1.3%

Value $4.152M Shares 424,979 Est. Cost $9.77 Unrealized —

— GENVEC INC 1.1%

Value $3.534M Shares 1,920,913 Est. Cost $2.08 Unrealized —

— CALITHERA BIOSCIENCES INC 1.0%

Value $3.183M Shares 415,480 Est. Cost $15.57 Unrealized —

— CYTOKINETICS INC 0.9%

Value $2.977M Shares 284,600 Est. Cost — Unrealized —

— ZAFGEN INC 0.7%

Value $2.321M Shares 369,000 Est. Cost $6.29 Unrealized —

— FORWARD PHARMA A/S 0.6%

Value $1.9M Shares 100,017 Est. Cost $23.61 Unrealized —

— AKARI THERAPEUTICS PLC 0.5%

Value $1.461M Shares 100,750 Est. Cost $24.00 Unrealized —

— GILEAD SCIENCES INC 0.4%

Value $1.194M Shares 11,800 Est. Cost — Unrealized —

— NEPHROGENEX INC 0.3%

Value $941K Shares 588,235 Est. Cost $1.60 Unrealized —

— QLT INC 0.1%

Value $266K Shares 100,000 Est. Cost $3.58 Unrealized —

— ZAFGEN INC 0.0%

Value $63,000 Shares 10,000 Est. Cost — Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
—	FIBROGEN INC	1,216,473	$37.07M	11.6%	$24.72	—	COM	31572Q808
—	FIVE PRIME THERAPEUTICS INC	719,000	$29.84M	9.4%	$36.09	—	COM	33830X104
—	JAZZ PHARMACEUTICALS	189,200	$26.59M	8.4%	—	—	Call	G50871905
—	RETROPHIN INC	1,224,384	$23.62M	7.4%	$21.12	—	COM	761299106
—	ARRAY BIOPHARMA INC	22,534	$21.63M	6.8%	$0.96	—	NOTE	04269XAA3
KURA	KURA ONCOLOGY INC	2,450,000	$20.58M	6.5%	$10.42	0.0%	COM	50127T109
—	ASSEMBLY BIOSCIENCES INC	2,098,302	$15.76M	4.9%	$9.53	—	COM	045396108
CYTK	CYTOKINETICS INC	1,418,700	$14.84M	4.7%	$9.81	0.0%	COM	23282W605
—	VALEANT PHARMACEUTICALS INTL	126,500	$12.86M	4.0%	—	—	Call	91911K902
COLL	COLLEGIUM PHARMACEUTICAL INC	465,118	$12.79M	4.0%	$17.29	+21.8%	COM	19459J104
—	EPIZYME INC	698,900	$11.2M	3.5%	$19.11	—	COM	29428V104
GLPG	GALAPAGOS	167,361	$10.52M	3.3%	$62.88	—	SPONSORED ADR	36315X101
—	KITE PHARMA INC	166,000	$10.23M	3.2%	$57.67	—	COM	49803L109
—	FLEX PHARMA INC	795,088	$9.899M	3.1%	$19.13	—	COM	33938A105
IRWD	IRONWOOD PHARMACEUTICALS	821,531	$9.522M	3.0%	$9.66	0.0%	COM CL A	46333X108
—	NABRIVA THERAPEUTICS AG	838,680	$7.931M	2.5%	$9.50	—	SPONSORED ADR	62957M104
—	ATYR PHARMA INC	790,462	$7.77M	2.4%	$18.52	—	COM	002120103
—	KINDRED BIOSCIENCES INC	1,432,765	$4.871M	1.5%	$7.10	—	COM	494577109
—	RETROPHIN INC	244,100	$4.709M	1.5%	—	—	Call	761299906
—	CELLADON CORP	2,843,170	$4.179M	1.3%	$1.26	—	COM	15117E107
—	OVASCIENCE INC	424,979	$4.152M	1.3%	$9.77	—	COM	69014Q101
—	GENVEC INC	1,920,913	$3.534M	1.1%	$2.08	—	COM	37246C307
—	CALITHERA BIOSCIENCES INC	415,480	$3.183M	1.0%	$15.57	—	COM	13089P101
—	CYTOKINETICS INC	284,600	$2.977M	0.9%	—	—	Call	23282W905
—	ZAFGEN INC	369,000	$2.321M	0.7%	$6.29	—	COM	98885E103
—	FORWARD PHARMA A/S	100,017	$1.9M	0.6%	$23.61	—	SPONSORED ADR	34986J105
—	AKARI THERAPEUTICS PLC	100,750	$1.461M	0.5%	$24.00	—	SPONSORED ADR	00972G108
—	GILEAD SCIENCES INC	11,800	$1.194M	0.4%	—	—	Call	375558903
—	NEPHROGENEX INC	588,235	$941K	0.3%	$1.60	—	COM	640667101
—	QLT INC	100,000	$266K	0.1%	$3.58	—	COM	746927102
—	ZAFGEN INC	10,000	$63,000	0.0%	—	—	Call	98885E903