TCG Crossover Management, LLC Diversified Active

Location: Palo Alto, CA

CIK: 0001839948 · Show all filings

Period: Q3 2024 (← Previous) (Next →)

Filing Date: Nov 14, 2024

Total Value: $1.18B (100.0% shares, 0.0% debt)

Holdings (36)

CGON CG ONCOLOGY, INC. 11.7%

Value $138M Shares 3,670,206 Share Price $37.73 * Est. Cost/Share $40.67 Unrealized @ Report Date -13.8%

DYN DYNE THERAPEUTICS, INC 8.1%

Value $95.19M Shares 2,650,150 Share Price $35.92 * Est. Cost/Share $16.62 Unrealized @ Report Date +139.5%

COGT COGENT BIOSCIENCES INC 6.4%

Value $75.22M Shares 6,964,375 Share Price $10.80 * Est. Cost/Share $9.05 Unrealized @ Report Date +7.6%

ABVX Abivax SA 5.9%

Value $69.77M Shares 6,056,596 Share Price $11.52 Est. Cost/Share $12.76 Unrealized @ Report Date —

EWTX EDGEWISE THERAPEUTICS, INC. 4.8%

Value $56.4M Shares 2,112,984 Share Price $26.69 * Est. Cost/Share $15.89 Unrealized @ Report Date +25.2%

SLN SILENCE THERAPEUTICS PLC 4.7%

Value $55.15M Shares 3,033,560 Share Price $18.18 Est. Cost/Share $14.21 Unrealized @ Report Date —

SVRA SAVARA INC. 4.4%

Value $52.42M Shares 12,362,205 Share Price $4.24 * Est. Cost/Share $3.73 Unrealized @ Report Date +18.3%

KROS KEROS THERAPEUTICS, INC. 4.3%

Value $51.06M Shares 879,344 Share Price $58.07 * Est. Cost/Share $59.30 Unrealized @ Report Date -16.7%

XNCR XENCOR INC 4.1%

Value $48.81M Shares 2,427,138 Share Price $20.11 * Est. Cost/Share $18.77 Unrealized @ Report Date 0.0%

TYRA TYRA BIOSCIENCES INC 4.0%

Value $46.76M Shares 1,989,103 Share Price $23.51 * Est. Cost/Share $12.71 Unrealized @ Report Date +65.2%

GPCR STRUCTURE THERAPEUTICS INC 4.0%

Value $46.66M Shares 1,063,000 Share Price $43.89 Est. Cost/Share $43.45 Unrealized @ Report Date —

OCUL OCULAR THERAPEUTIX, INC. 3.9%

Value $46.28M Shares 5,319,148 Share Price $8.70 * Est. Cost/Share $7.10 Unrealized @ Report Date +16.1%

CNTA CENTESSA PHARMACEUTICALS PLC 3.9%

Value $46.22M Shares 2,890,816 Share Price $15.99 Est. Cost/Share $7.22 Unrealized @ Report Date —

— TOURMALINE BIO INC 3.2%

Value $37.99M Shares 1,477,593 Share Price $25.71 Est. Cost/Share $25.14 Unrealized @ Report Date —

— THIRD HARMONIC BIO INC 2.8%

Value $32.72M Shares 2,415,000 Share Price $13.55 Est. Cost/Share $13.55 Unrealized @ Report Date —

— ASTRIA THERAPEUTICS, INC. 2.6%

Value $30.41M Shares 2,761,861 Share Price $11.01 Est. Cost/Share $14.07 Unrealized @ Report Date —

MLYS MINERALYS THERAPEUTICS, INC. 2.5%

Value $29.91M Shares 2,470,265 Share Price $12.11 Est. Cost/Share $12.35 Unrealized @ Report Date -2.0%

KURA KURA ONCOLOGY INC 2.4%

Value $27.82M Shares 1,423,642 Share Price $19.54 * Est. Cost/Share $14.54 Unrealized @ Report Date +39.3%

SLNO SOLENO THERAPEUTIVS, INC. 2.4%

Value $27.77M Shares 550,000 Share Price $50.49 * Est. Cost/Share $47.87 Unrealized @ Report Date 0.0%

CMPS COMPASS PATHWAYS PLC 2.1%

Value $24.31M Shares 3,858,000 Share Price $6.30 Est. Cost/Share $7.40 Unrealized @ Report Date —

IRON Disc Medicine, Inc. 2.0%

Value $23.93M Shares 486,957 Share Price $49.14 * Est. Cost/Share $33.98 Unrealized @ Report Date +38.2%

FULC FULCRUM THERAPEUTICS INC 1.6%

Value $18.74M Shares 5,250,000 Share Price $3.57 * Est. Cost/Share $7.42 Unrealized @ Report Date 0.0%

MBX MBX BIOSCIENCES INC 1.4%

Value $16.89M Shares 650,000 Share Price $25.98 * Est. Cost/Share $22.87 Unrealized @ Report Date 0.0%

AMLX AMYLYX PHARMACEUTICALS INC 1.3%

Value $15.05M Shares 4,643,812 Share Price $3.24 * Est. Cost/Share $2.25 Unrealized @ Report Date 0.0%

— ADVERUM BIOTECHNOLOGIES, INC. 1.2%

Value $14.1M Shares 2,008,339 Share Price $7.02 Est. Cost/Share $7.02 Unrealized @ Report Date —

TRDA ENTRADA THERAPEUTICS INC 0.8%

Value $9.348M Shares 584,955 Share Price $15.98 Est. Cost/Share $17.12 Unrealized @ Report Date —

VTGN VISTAGEN THERAPEUTICS INC 0.7%

Value $8.057M Shares 2,676,580 Share Price $3.01 * Est. Cost/Share $3.41 Unrealized @ Report Date 0.0%

TARS TARSUS PHARMACEUTICALS, INC. 0.6%

Value $7.625M Shares 231,820 Share Price $32.89 * Est. Cost/Share $17.70 Unrealized @ Report Date +58.8%

EYPT EyePoint Pharmaceuticals, Inc. 0.6%

Value $7.369M Shares 922,335 Share Price $7.99 * Est. Cost/Share $13.97 Unrealized @ Report Date -37.1%

— NEKTAR THERAPEUTICS 0.4%

Value $5.2M Shares 4,000,000 Share Price $1.30 Est. Cost/Share $0.93 Unrealized @ Report Date —

— AEROVATE THERAPEUTICS INC 0.4%

Value $4.683M Shares 2,240,809 Share Price $2.09 Est. Cost/Share $15.50 Unrealized @ Report Date —

AVTX AVALO THERAPEUTICS INC 0.4%

Value $4.588M Shares 483,000 Share Price $9.50 * Est. Cost/Share $10.31 Unrealized @ Report Date 0.0%

KOD KODIAK SCIENCES INC 0.2%

Value $2.631M Shares 1,008,158 Share Price $2.61 Est. Cost/Share $3.95 Unrealized @ Report Date -32.7%

ANTX AN2 Therapeutics, Inc. 0.1%

Value $1.664M Shares 1,555,118 Share Price $1.07 * Est. Cost/Share $9.33 Unrealized @ Report Date -81.4%

VTYX VENTYX BIOSCIENCES, INC 0.1%

Value $689K Shares 316,195 Share Price $2.18 * Est. Cost/Share $29.94 Unrealized @ Report Date -92.3%

CABA CABALETTA BIO, INC 0.0%

Value $410K Shares 86,795 Share Price $4.72 * Est. Cost/Share $3.64 Unrealized @ Report Date +58.9%

Ticker	Issuer	Shares	Value	%	Share Price	Est. Cost/Share	Unrealized @ Report Date	Class	CUSIP
CGON	CG ONCOLOGY, INC.	3,670,206	$138M	11.7%	$37.73 *	$40.67	-13.8%	COMM	156944100
DYN	DYNE THERAPEUTICS, INC	2,650,150	$95.19M	8.1%	$35.92 *	$16.62	+139.5%	COMM	26818M108
COGT	COGENT BIOSCIENCES INC	6,964,375	$75.22M	6.4%	$10.80 *	$9.05	+7.6%	COMM	19240Q201
ABVX	Abivax SA	6,056,596	$69.77M	5.9%	$11.52	$12.76	—	ADRS	00370M103
EWTX	EDGEWISE THERAPEUTICS, INC.	2,112,984	$56.4M	4.8%	$26.69 *	$15.89	+25.2%	COMM	28036F105
SLN	SILENCE THERAPEUTICS PLC	3,033,560	$55.15M	4.7%	$18.18	$14.21	—	ADRS	82686Q101
SVRA	SAVARA INC.	12,362,205	$52.42M	4.4%	$4.24 *	$3.73	+18.3%	COMM	805111101
KROS	KEROS THERAPEUTICS, INC.	879,344	$51.06M	4.3%	$58.07 *	$59.30	-16.7%	COMM	492327101
XNCR	XENCOR INC	2,427,138	$48.81M	4.1%	$20.11 *	$18.77	0.0%	COMM	98401F105
TYRA	TYRA BIOSCIENCES INC	1,989,103	$46.76M	4.0%	$23.51 *	$12.71	+65.2%	COMM	90240B106
GPCR	STRUCTURE THERAPEUTICS INC	1,063,000	$46.66M	4.0%	$43.89	$43.45	—	ADRS	86366E106
OCUL	OCULAR THERAPEUTIX, INC.	5,319,148	$46.28M	3.9%	$8.70 *	$7.10	+16.1%	COMM	67576A100
CNTA	CENTESSA PHARMACEUTICALS PLC	2,890,816	$46.22M	3.9%	$15.99	$7.22	—	COMM	152309100
—	TOURMALINE BIO INC	1,477,593	$37.99M	3.2%	$25.71	$25.14	—	COMM	89157D105
—	THIRD HARMONIC BIO INC	2,415,000	$32.72M	2.8%	$13.55	$13.55	—	COMM	88427A107
—	ASTRIA THERAPEUTICS, INC.	2,761,861	$30.41M	2.6%	$11.01	$14.07	—	COMM	04635X102
MLYS	MINERALYS THERAPEUTICS, INC.	2,470,265	$29.91M	2.5%	$12.11	$12.35	-2.0%	COMM	603170101
KURA	KURA ONCOLOGY INC	1,423,642	$27.82M	2.4%	$19.54 *	$14.54	+39.3%	COMM	50127T109
SLNO	SOLENO THERAPEUTIVS, INC.	550,000	$27.77M	2.4%	$50.49 *	$47.87	0.0%	COMM	834203309
CMPS	COMPASS PATHWAYS PLC	3,858,000	$24.31M	2.1%	$6.30	$7.40	—	ADRS	20451W101
IRON	Disc Medicine, Inc.	486,957	$23.93M	2.0%	$49.14 *	$33.98	+38.2%	COMM	254604101
FULC	FULCRUM THERAPEUTICS INC	5,250,000	$18.74M	1.6%	$3.57 *	$7.42	0.0%	COMM	359616109
MBX	MBX BIOSCIENCES INC	650,000	$16.89M	1.4%	$25.98 *	$22.87	0.0%	COMM	55287L101
AMLX	AMYLYX PHARMACEUTICALS INC	4,643,812	$15.05M	1.3%	$3.24 *	$2.25	0.0%	COMM	03237H101
—	ADVERUM BIOTECHNOLOGIES, INC.	2,008,339	$14.1M	1.2%	$7.02	$7.02	—	COMM	00773U207
TRDA	ENTRADA THERAPEUTICS INC	584,955	$9.348M	0.8%	$15.98	$17.12	—	COMM	29384C108
VTGN	VISTAGEN THERAPEUTICS INC	2,676,580	$8.057M	0.7%	$3.01 *	$3.41	0.0%	COMM	92840H400
TARS	TARSUS PHARMACEUTICALS, INC.	231,820	$7.625M	0.6%	$32.89 *	$17.70	+58.8%	COMM	87650L103
EYPT	EyePoint Pharmaceuticals, Inc.	922,335	$7.369M	0.6%	$7.99 *	$13.97	-37.1%	COMM	30233G209
—	NEKTAR THERAPEUTICS	4,000,000	$5.2M	0.4%	$1.30	$0.93	—	COMM	640268108
—	AEROVATE THERAPEUTICS INC	2,240,809	$4.683M	0.4%	$2.09	$15.50	—	COMM	008064107
AVTX	AVALO THERAPEUTICS INC	483,000	$4.588M	0.4%	$9.50 *	$10.31	0.0%	COMM	05338F306
KOD	KODIAK SCIENCES INC	1,008,158	$2.631M	0.2%	$2.61	$3.95	-32.7%	COMM	50015M109
ANTX	AN2 Therapeutics, Inc.	1,555,118	$1.664M	0.1%	$1.07 *	$9.33	-81.4%	COMM	037326105
VTYX	VENTYX BIOSCIENCES, INC	316,195	$689K	0.1%	$2.18 *	$29.94	-92.3%	COMM	92332V107
CABA	CABALETTA BIO, INC	86,795	$410K	0.0%	$4.72 *	$3.64	+58.9%	COMM	12674W109