AIGH Capital Management LLC Quant / Systematic

Location: Baltimore, MD

CIK: 0001835943 · Show all filings

Period: Q4 2025 (← Previous) (Next →)

Filing Date: Feb 2, 2026

Total Value: $413M (100.0% shares, 0.0% debt)

Holdings (34)

SNDK SANDISK CORP 16.1%

Value $66.47M Shares 280,000 Est. Cost $58.39 Unrealized +243.0%

— ZOOM COMMUNICATIONS INC 14.6%

Value $60.4M Shares 700,000 Est. Cost — Unrealized —

CSTL CASTLE BIOSCIENCES INC 5.9%

Value $24.3M Shares 624,719 Est. Cost $20.31 Unrealized +58.7%

PSNL PERSONALIS INC 5.6%

Value $23.08M Shares 2,900,000 Est. Cost $4.21 Unrealized +107.7%

LASR NLIGHT INC 5.4%

Value $22.51M Shares 600,103 Est. Cost $12.42 Unrealized +168.8%

DAWN DAY ONE BIOPHARMACEUTICALS 4.5%

Value $18.57M Shares 1,992,021 Est. Cost $7.23 Unrealized +15.6%

VNDA VANDA PHARMACEUTICALS INC 4.3%

Value $17.63M Shares 1,998,431 Est. Cost $5.50 Unrealized 0.0%

BKTI BK TECHNOLOGIES CORPORATION 3.8%

Value $15.77M Shares 211,453 Est. Cost $64.84 Unrealized +10.5%

DOMO DOMO INC 3.7%

Value $15.49M Shares 1,837,762 Est. Cost $9.68 Unrealized +21.5%

ESPR ESPERION THERAPEUTICS INC 3.6%

Value $14.8M Shares 4,000,000 Est. Cost $2.26 Unrealized +43.1%

KYTX KYVERNA THERAPEUTICS INC 3.4%

Value $14.1M Shares 1,500,000 Est. Cost $7.42 Unrealized 0.0%

FENC FENNEC PHARMACEUTICALS INC 2.9%

Value $12.18M Shares 1,581,501 Est. Cost $7.79 Unrealized +5.4%

LPTH LIGHTPATH TECHNOLOGIES INC 2.7%

Value $11.13M Shares 1,030,738 Est. Cost $2.64 Unrealized +206.7%

ABEO ABEONA THERAPEUTICS INC 2.6%

Value $10.54M Shares 2,000,000 Est. Cost $5.03 Unrealized 0.0%

— ZEVRA THERAPEUTICS INC 2.2%

Value $8.96M Shares 1,000,000 Est. Cost — Unrealized —

IDN INTELLICHECK INC 2.0%

Value $8.106M Shares 1,213,434 Est. Cost $5.64 Unrealized 0.0%

LRMR LARIMAR THERAPEUTICS INC 1.8%

Value $7.62M Shares 2,000,000 Est. Cost $3.82 Unrealized +1.8%

ARQ ARQ INC 1.8%

Value $7.433M Shares 2,273,092 Est. Cost $6.70 Unrealized -27.1%

ARDX ARDELYX INC 1.6%

Value $6.705M Shares 1,150,000 Est. Cost $5.55 Unrealized +0.4%

BYRN BYRNA TECHNOLOGIES INC 1.6%

Value $6.63M Shares 394,906 Est. Cost $19.47 Unrealized 0.0%

PYPD POLYPID LTD 1.4%

Value $5.828M Shares 1,342,972 Est. Cost $4.20 Unrealized -11.7%

COYA COYA THERAPEUTICS INC 1.4%

Value $5.657M Shares 975,404 Est. Cost $5.88 Unrealized +3.4%

— SEAGATE TECHNOLOGY HLDNGS 1.3%

Value $5.508M Shares 20,000 Est. Cost — Unrealized —

TLPH TALPHERA INC 1.3%

Value $5.314M Shares 4,661,502 Est. Cost $0.61 Unrealized +98.3%

APYX APYX MEDICAL CORPORATION 0.9%

Value $3.867M Shares 1,104,970 Est. Cost $3.49 Unrealized 0.0%

RNXT RENOVORX INC 0.9%

Value $3.671M Shares 2,833,894 Est. Cost $1.15 Unrealized -13.0%

GRCE GRACE THERAPEUTICS INC 0.8%

Value $3.146M Shares 907,217 Est. Cost $3.26 Unrealized -2.5%

ELUT ELUTIA INC 0.5%

Value $2.125M Shares 3,068,185 Est. Cost $3.27 Unrealized -76.8%

NRXS NEURAXIS INC 0.4%

Value $1.816M Shares 400,000 Est. Cost $2.35 Unrealized +27.4%

IPWR IDEAL PWR INC 0.4%

Value $1.52M Shares 491,989 Est. Cost $8.81 Unrealized -50.0%

SMTK SMARTKEM INC 0.2%

Value $719K Shares 675,000 Est. Cost $2.98 Unrealized -40.1%

QNRX QUOIN PHARMACEUTICALS LTD 0.2%

Value $712K Shares 49,323 Est. Cost $14.43 Unrealized —

BFRI BIOFRONTERA INC 0.1%

Value $522K Shares 915,210 Est. Cost $1.08 Unrealized -16.1%

APRE APREA THERAPEUTICS INC 0.1%

Value $316K Shares 370,541 Est. Cost $6.87 Unrealized -82.1%

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
SNDK	SANDISK CORP	280,000	$66.47M	16.1%	$58.39	+243.0%	COM	80004C200
—	ZOOM COMMUNICATIONS INC	700,000	$60.4M	14.6%	—	—	Call	98980L901
CSTL	CASTLE BIOSCIENCES INC	624,719	$24.3M	5.9%	$20.31	+58.7%	COM	14843C105
PSNL	PERSONALIS INC	2,900,000	$23.08M	5.6%	$4.21	+107.7%	COM	71535D106
LASR	NLIGHT INC	600,103	$22.51M	5.4%	$12.42	+168.8%	COM	65487K100
DAWN	DAY ONE BIOPHARMACEUTICALS	1,992,021	$18.57M	4.5%	$7.23	+15.6%	COM	23954D109
VNDA	VANDA PHARMACEUTICALS INC	1,998,431	$17.63M	4.3%	$5.50	0.0%	COM	921659108
BKTI	BK TECHNOLOGIES CORPORATION	211,453	$15.77M	3.8%	$64.84	+10.5%	COM NEW	05587G203
DOMO	DOMO INC	1,837,762	$15.49M	3.7%	$9.68	+21.5%	COM CL B	257554105
ESPR	ESPERION THERAPEUTICS INC	4,000,000	$14.8M	3.6%	$2.26	+43.1%	COM	29664W105
KYTX	KYVERNA THERAPEUTICS INC	1,500,000	$14.1M	3.4%	$7.42	0.0%	COM	501976104
FENC	FENNEC PHARMACEUTICALS INC	1,581,501	$12.18M	2.9%	$7.79	+5.4%	COM	31447P100
LPTH	LIGHTPATH TECHNOLOGIES INC	1,030,738	$11.13M	2.7%	$2.64	+206.7%	COM CL A	532257805
ABEO	ABEONA THERAPEUTICS INC	2,000,000	$10.54M	2.6%	$5.03	0.0%	COM NEW	00289Y206
—	ZEVRA THERAPEUTICS INC	1,000,000	$8.96M	2.2%	—	—	Call	488445906
IDN	INTELLICHECK INC	1,213,434	$8.106M	2.0%	$5.64	0.0%	COM NEW	45817G201
LRMR	LARIMAR THERAPEUTICS INC	2,000,000	$7.62M	1.8%	$3.82	+1.8%	COM	517125100
ARQ	ARQ INC	2,273,092	$7.433M	1.8%	$6.70	-27.1%	COM	00770C101
ARDX	ARDELYX INC	1,150,000	$6.705M	1.6%	$5.55	+0.4%	COM	039697107
BYRN	BYRNA TECHNOLOGIES INC	394,906	$6.63M	1.6%	$19.47	0.0%	COM NEW	12448X201
PYPD	POLYPID LTD	1,342,972	$5.828M	1.4%	$4.20	-11.7%	COM	M8001Q126
COYA	COYA THERAPEUTICS INC	975,404	$5.657M	1.4%	$5.88	+3.4%	COMMON STOCK	22407B108
—	SEAGATE TECHNOLOGY HLDNGS	20,000	$5.508M	1.3%	—	—	Call	G7997R903
TLPH	TALPHERA INC	4,661,502	$5.314M	1.3%	$0.61	+98.3%	COM NEW	00444T209
APYX	APYX MEDICAL CORPORATION	1,104,970	$3.867M	0.9%	$3.49	0.0%	COM	03837C106
RNXT	RENOVORX INC	2,833,894	$3.671M	0.9%	$1.15	-13.0%	COM NEW	75989R107
GRCE	GRACE THERAPEUTICS INC	907,217	$3.146M	0.8%	$3.26	-2.5%	COM	00439U104
ELUT	ELUTIA INC	3,068,185	$2.125M	0.5%	$3.27	-76.8%	CL A COM	05479K106
NRXS	NEURAXIS INC	400,000	$1.816M	0.4%	$2.35	+27.4%	COM	64134X201
IPWR	IDEAL PWR INC	491,989	$1.52M	0.4%	$8.81	-50.0%	COM NEW	451622203
SMTK	SMARTKEM INC	675,000	$719K	0.2%	$2.98	-40.1%	COM NEW	83193D203
QNRX	QUOIN PHARMACEUTICALS LTD	49,323	$712K	0.2%	$14.43	—	SPONSORED ADS	74907L409
BFRI	BIOFRONTERA INC	915,210	$522K	0.1%	$1.08	-16.1%	COM NEW	09077D209
APRE	APREA THERAPEUTICS INC	370,541	$316K	0.1%	$6.87	-82.1%	COM NEW	03836J201