Sio Capital Management, LLC Hedge Fund

Location: New York, NY

CIK: 0001482416 · Show all filings

Period: Q4 2025 (← Previous) (Next →)

Filing Date: Feb 17, 2026

Total Value: $636M (100.0% shares, 0.0% debt)

Holdings (68)

CELC CELCUITY INC 7.5%
Value $47.58M Shares 477,067 Share Price $99.74 * Est. Cost/Share $40.03 Unrealized @ Report Date +105.4%
CI THE CIGNA GROUP 7.5%
Value $47.4M Shares 172,203 Share Price $275.23 Est. Cost/Share $279.23 Unrealized @ Report Date 0.0%
SNY SANOFI SA 7.4%
Value $47.09M Shares 971,686 Share Price $48.46 Est. Cost/Share $47.94 Unrealized @ Report Date —
MMS MAXIMUS INC 6.8%
Value $43.19M Shares 500,304 Share Price $86.32 Est. Cost/Share $80.51 Unrealized @ Report Date +6.2%
ZBH ZIMMER BIOMET HOLDINGS INC 5.5%
Value $34.68M Shares 385,642 Share Price $89.92 * Est. Cost/Share $94.58 Unrealized @ Report Date 0.0%
RYTM RHYTHM PHARMACEUTICALS INC 4.5%
Value $28.44M Shares 265,700 Share Price $107.04 Est. Cost/Share — Unrealized @ Report Date —
KVUE KENVUE INC 4.0%
Value $25.28M Shares 1,465,442 Share Price $17.25 * Est. Cost/Share $18.45 Unrealized @ Report Date -11.9%
OGN ORGANON & CO 3.9%
Value $24.53M Shares 3,421,765 Share Price $7.17 * Est. Cost/Share $7.89 Unrealized @ Report Date 0.0%
ICLR ICON PLC 3.6%
Value $23.18M Shares 127,202 Share Price $182.22 * Est. Cost/Share $178.08 Unrealized @ Report Date 0.0%
WAY WAYSTAR HLDG CORP 3.2%
Value $20.1M Shares 613,725 Share Price $32.75 * Est. Cost/Share $35.62 Unrealized @ Report Date 0.0%
LIVN LIVANOVA PLC 3.1%
Value $19.84M Shares 322,382 Share Price $61.53 * Est. Cost/Share $57.14 Unrealized @ Report Date 0.0%
DNTH DIANTHUS THERAPEUTICS INC 3.1%
Value $19.55M Shares 474,503 Share Price $41.21 * Est. Cost/Share $23.44 Unrealized @ Report Date +65.4%
BHVN BIOHAVEN LTD 2.2%
Value $14.05M Shares 1,244,764 Share Price $11.29 * Est. Cost/Share $12.39 Unrealized @ Report Date 0.0%
GPCR STRUCTURE THERAPEUTICS INC 2.2%
Value $14.01M Shares 201,500 Share Price $69.55 Est. Cost/Share $69.55 Unrealized @ Report Date —
BMRN BIOMARIN PHARMACEUTICAL INC 2.2%
Value $13.83M Shares 232,688 Share Price $59.43 * Est. Cost/Share $63.83 Unrealized @ Report Date -14.7%
TYRA TYRA BIOSCIENCES INC 2.2%
Value $13.83M Shares 526,002 Share Price $26.29 * Est. Cost/Share $12.45 Unrealized @ Report Date +47.5%
BTSG BRIGHTSPRING HEALTH SVCS INC 1.8%
Value $11.53M Shares 308,010 Share Price $37.45 * Est. Cost/Share $33.54 Unrealized @ Report Date 0.0%
CNC CENTENE CORP DEL 1.8%
Value $11.29M Shares 274,350 Share Price $41.15 * Est. Cost/Share $49.47 Unrealized @ Report Date -24.3%
CRL CHARLES RIV LABS INTL INC 1.7%
Value $10.97M Shares 54,985 Share Price $199.48 * Est. Cost/Share $181.39 Unrealized @ Report Date 0.0%
TFX TELEFLEX INCORPORATED 1.7%
Value $10.6M Shares 86,876 Share Price $122.04 Est. Cost/Share $120.84 Unrealized @ Report Date +0.1%
AVR ANTERIS TECHNOLOGIES GLOBAL 1.5%
Value $9.354M Shares 1,874,641 Share Price $4.99 * Est. Cost/Share $5.54 Unrealized @ Report Date -17.2%
TARA PROTARA THERAPEUTICS INC 1.4%
Value $9.143M Shares 1,715,394 Share Price $5.33 * Est. Cost/Share $5.56 Unrealized @ Report Date 0.0%
CCRN CROSS CTRY HEALTHCARE INC 1.4%
Value $8.657M Shares 1,068,821 Share Price $8.10 * Est. Cost/Share $10.93 Unrealized @ Report Date 0.0%
HAE HAEMONETICS CORP MASS 1.2%
Value $7.424M Shares 92,631 Share Price $80.15 * Est. Cost/Share $61.90 Unrealized @ Report Date +8.5%
ANIP ANI PHARMACEUTICALS INC 1.1%
Value $6.889M Shares 87,272 Share Price $78.94 * Est. Cost/Share $69.07 Unrealized @ Report Date +25.4%
AQST AQUESTIVE THERAPEUTICS INC 1.0%
Value $6.415M Shares 993,095 Share Price $6.46 * Est. Cost/Share $3.44 Unrealized @ Report Date +80.9%
DRUG BRIGHT MINDS BIOSCIENCES INC 1.0%
Value $6.39M Shares 81,883 Share Price $78.04 * Est. Cost/Share $35.35 Unrealized @ Report Date +89.1%
EWTX EDGEWISE THERAPEUTICS INC 0.9%
Value $5.893M Shares 237,481 Share Price $24.81 * Est. Cost/Share $14.42 Unrealized @ Report Date +39.2%
ABVX ABIVAX SA 0.9%
Value $5.815M Shares 43,124 Share Price $134.85 Est. Cost/Share $134.85 Unrealized @ Report Date —
CRNX CRINETICS PHARMACEUTICALS IN 0.9%
Value $5.811M Shares 124,841 Share Price $46.55 * Est. Cost/Share $31.97 Unrealized @ Report Date +39.2%
RAPP RAPPORT THERAPEUTICS INC 0.9%
Value $5.621M Shares 185,265 Share Price $30.34 * Est. Cost/Share $17.84 Unrealized @ Report Date +55.1%
COR CENCORA INC 0.8%
Value $5.37M Shares 15,900 Share Price $337.75 Est. Cost/Share $340.62 Unrealized @ Report Date 0.0%
MCK MCKESSON CORP 0.8%
Value $5.25M Shares 6,400 Share Price $820.29 Est. Cost/Share $815.57 Unrealized @ Report Date 0.0%
IRON DISC MEDICINE INC 0.7%
Value $4.573M Shares 57,586 Share Price $79.41 * Est. Cost/Share $43.62 Unrealized @ Report Date +93.7%
PRQR PROQR THERAPEUTICS N V 0.7%
Value $4.372M Shares 2,164,181 Share Price $2.02 * Est. Cost/Share $3.13 Unrealized @ Report Date -25.2%
FULC FULCRUM THERAPEUTICS INC 0.7%
Value $4.32M Shares 382,000 Share Price $11.31 * Est. Cost/Share $10.18 Unrealized @ Report Date 0.0%
SVRA SAVARA INC 0.6%
Value $3.702M Shares 613,888 Share Price $6.03 * Est. Cost/Share $2.76 Unrealized @ Report Date +77.2%
ORKA ORUKA THERAPEUTICS INC 0.6%
Value $3.58M Shares 118,126 Share Price $30.31 * Est. Cost/Share $27.86 Unrealized @ Report Date 0.0%
VTYX VENTYX BIOSCIENCES INC 0.6%
Value $3.501M Shares 387,751 Share Price $9.03 * Est. Cost/Share $2.68 Unrealized @ Report Date +179.0%
PMVP PMV PHARMACEUTICALS INC 0.5%
Value $3.296M Shares 2,636,548 Share Price $1.25 * Est. Cost/Share $1.73 Unrealized @ Report Date -22.5%
SI SHOULDER INNOVATIONS INC 0.5%
Value $3.26M Shares 227,971 Share Price $14.30 * Est. Cost/Share $13.97 Unrealized @ Report Date -2.4%
ALGS ALIGOS THERAPEUTICS INC 0.5%
Value $3.131M Shares 335,937 Share Price $9.32 Est. Cost/Share $14.55 Unrealized @ Report Date -35.2%
VIR VIR BIOTECHNOLOGY INC 0.5%
Value $2.884M Shares 478,343 Share Price $6.03 Est. Cost/Share $7.89 Unrealized @ Report Date -24.5%
ALKS ALKERMES PLC 0.4%
Value $2.668M Shares 95,353 Share Price $27.98 * Est. Cost/Share $28.20 Unrealized @ Report Date +6.2%
IDYA IDEAYA BIOSCIENCES INC 0.4%
Value $2.618M Shares 75,730 Share Price $34.57 * Est. Cost/Share $37.74 Unrealized @ Report Date -15.5%
KYMR KYMERA THERAPEUTICS INC 0.4%
Value $2.508M Shares 32,235 Share Price $77.81 * Est. Cost/Share $67.53 Unrealized @ Report Date 0.0%
ELTX ELICIO THERAPEUTICS INC 0.4%
Value $2.363M Shares 296,900 Share Price $7.96 Est. Cost/Share — Unrealized @ Report Date —
OVID OVID THERAPEUTICS INC 0.4%
Value $2.327M Shares 1,427,495 Share Price $1.63 * Est. Cost/Share $0.84 Unrealized @ Report Date +83.2%
CNTX CONTEXT THERAPEUTICS INC 0.3%
Value $1.972M Shares 1,341,636 Share Price $1.47 * Est. Cost/Share $1.71 Unrealized @ Report Date -31.8%
HYPR HYPERFINE INC 0.3%
Value $1.959M Shares 2,000,000 Share Price $0.98 * Est. Cost/Share $1.21 Unrealized @ Report Date 0.0%
OTLK OUTLOOK THERAPEUTICS INC 0.3%
Value $1.778M Shares 1,125,400 Share Price $1.58 Est. Cost/Share — Unrealized @ Report Date —
BBOT BRIDGEBIO ONCOLOGY THERAPEUT 0.3%
Value $1.635M Shares 130,628 Share Price $12.52 Est. Cost/Share $11.58 Unrealized @ Report Date —
IBIO IBIO INC 0.2%
Value $1.428M Shares 740,000 Share Price $1.93 * Est. Cost/Share $1.36 Unrealized @ Report Date 0.0%
XLO XILIO THERAPEUTICS INC 0.2%
Value $1.367M Shares 2,134,537 Share Price $0.64 * Est. Cost/Share $0.75 Unrealized @ Report Date 0.0%
ADGM ADAGIO MED HLDGS INC 0.2%
Value $1.34M Shares 1,288,461 Share Price $1.04 * Est. Cost/Share $1.19 Unrealized @ Report Date 0.0%
AVTX AVALO THERAPEUTICS INC 0.2%
Value $1.311M Shares 72,173 Share Price $18.16 * Est. Cost/Share $11.82 Unrealized @ Report Date +42.8%
NMTC NEUROONE MED TECHNOLOGIES CO 0.1%
Value $864K Shares 1,140,040 Share Price $0.76 Est. Cost/Share $0.62 Unrealized @ Report Date +23.3%
TELA TELA BIO INC 0.1%
Value $751K Shares 636,300 Share Price $1.18 * Est. Cost/Share $2.80 Unrealized @ Report Date -54.7%
FHTX FOGHORN THERAPEUTICS INC 0.1%
Value $664K Shares 122,889 Share Price $5.40 * Est. Cost/Share $4.31 Unrealized @ Report Date +5.1%
SENS SENSEONICS HLDGS INC 0.1%
Value $639K Shares 115,784 Share Price $5.52 * Est. Cost/Share $6.96 Unrealized @ Report Date 0.0%
ENTA ENANTA PHARMACEUTICALS INC 0.1%
Value $631K Shares 40,000 Share Price $15.77 * Est. Cost/Share $12.70 Unrealized @ Report Date 0.0%
TERN TERNS PHARMACEUTICALS INC 0.1%
Value $408K Shares 10,100 Share Price $40.40 * Est. Cost/Share $8.18 Unrealized @ Report Date +182.6%
MODD MODULAR MED INC 0.0%
Value $286K Shares 785,824 Share Price $0.36 * Est. Cost/Share $1.38 Unrealized @ Report Date -64.4%
NYXH NYXOAH S A 0.0%
Value $234K Shares 50,839 Share Price $4.60 * Est. Cost/Share $7.82 Unrealized @ Report Date -34.2%
BOLD BOUNDLESS BIO INC 0.0%
Value $196K Shares 163,679 Share Price $1.20 Est. Cost/Share $13.58 Unrealized @ Report Date -90.8%
NXTC NEXTCURE INC 0.0%
Value $155K Shares 10,940 Share Price $14.19 * Est. Cost/Share $5.23 Unrealized @ Report Date +98.0%
RCKTW ROCKET PHARMACEUTICALS INC 0.0%
Value $7,200 Shares 400,000 Share Price $0.02 Est. Cost/Share $0.16 Unrealized @ Report Date —
HUMAW HUMACYTE INC 0.0%
Value $4,875 Shares 49,998 Share Price $0.10 Est. Cost/Share $0.60 Unrealized @ Report Date —