Ghost Tree Capital, LLC Hedge Fund

CIK: 0001595851 · Show all filings

Period: Q4 2018 (← Previous) (Next →)

Filing Date: Apr 9, 2020

Total Value: $276M (100.0% shares, 0.0% debt)

Holdings (40)

XBI SPDR SERIES TRUST 19.5%

Value $53.81M Shares 750,000 Share Price $71.75 Est. Cost/Share — Unrealized @ Report Date —

— MIRATI THERAPEUTICS INC 6.2%

Value $16.97M Shares 400,000 Share Price $42.42 Est. Cost/Share $33.00 Unrealized @ Report Date —

— DICERNA PHARMACEUTICALS INC 4.8%

Value $13.36M Shares 1,250,000 Share Price $10.69 Est. Cost/Share $11.55 Unrealized @ Report Date —

VRTX VERTEX PHARMACEUTICALS INC 4.8%

Value $13.26M Shares 80,000 Share Price $165.71 * Est. Cost/Share $173.27 Unrealized @ Report Date 0.0%

— IMMUNOMEDICS INC 4.1%

Value $11.42M Shares 800,000 Share Price $14.27 Est. Cost/Share $8.35 Unrealized @ Report Date —

— IMMUNOMEDICS INC 4.1%

Value $11.42M Shares 800,000 Share Price $14.27 Est. Cost/Share $8.35 Unrealized @ Report Date —

— RETROPHIN INC 4.1%

Value $11.31M Shares 500,000 Share Price $22.63 Est. Cost/Share $26.90 Unrealized @ Report Date —

— BIOHAVEN PHARMACTL HLDG CO L 3.7%

Value $10.17M Shares 275,000 Share Price $36.98 Est. Cost/Share $37.40 Unrealized @ Report Date —

ANAB ANAPTYSBIO INC 3.2%

Value $8.931M Shares 140,000 Share Price $63.79 * Est. Cost/Share $80.01 Unrealized @ Report Date -7.1%

RCKT ROCKET PHARMACEUTICALS INC 3.2%

Value $8.892M Shares 600,000 Share Price $14.82 * Est. Cost/Share $16.85 Unrealized @ Report Date -1.5%

IOVA IOVANCE BIOTHERAPEUTICS INC 3.2%

Value $8.85M Shares 1,000,000 Share Price $8.85 * Est. Cost/Share $9.64 Unrealized @ Report Date 0.0%

KALV KALVISTA PHARMACEUTICALS INC 3.0%

Value $8.394M Shares 425,000 Share Price $19.75 Est. Cost/Share $16.62 Unrealized @ Report Date +21.0%

ASND ASCENDIS PHARMA A S 2.8%

Value $7.831M Shares 125,000 Share Price $62.65 Est. Cost/Share $49.12 Unrealized @ Report Date —

SRPT SAREPTA THERAPEUTICS INC 2.8%

Value $7.639M Shares 70,000 Share Price $109.13 * Est. Cost/Share $78.35 Unrealized @ Report Date +59.6%

— OBSEVA SA 2.5%

Value $6.963M Shares 550,000 Share Price $12.66 Est. Cost/Share $11.87 Unrealized @ Report Date —

— AUDENTES THERAPEUTICS INC 2.3%

Value $6.396M Shares 300,000 Share Price $21.32 Est. Cost/Share $21.32 Unrealized @ Report Date —

FOLD AMICUS THERAPEUTICS INC 2.3%

Value $6.227M Shares 650,000 Share Price $9.58 * Est. Cost/Share $10.99 Unrealized @ Report Date 0.0%

— TRICIDA INC 2.1%

Value $5.895M Shares 250,000 Share Price $23.58 Est. Cost/Share $30.07 Unrealized @ Report Date —

FXF INVESCO CURNCYSHS SWISS FRAN 1.9%

Value $5.237M Shares 55,200 Share Price $94.87 Est. Cost/Share $95.31 Unrealized @ Report Date —

— ORCHARD THERAPEUTICS PLC 1.7%

Value $4.719M Shares 300,000 Share Price $15.73 Est. Cost/Share $15.73 Unrealized @ Report Date —

VRAYQ VIEWRAY INC 1.7%

Value $4.553M Shares 750,000 Share Price $6.07 * Est. Cost/Share $6.99 Unrealized @ Report Date +7.3%

— KADMON HLDGS INC 1.5%

Value $4.16M Shares 2,000,000 Share Price $2.08 Est. Cost/Share $3.85 Unrealized @ Report Date —

— GLOBAL BLOOD THERAPEUTICS IN 1.5%

Value $4.105M Shares 100,000 Share Price $41.05 Est. Cost/Share $41.55 Unrealized @ Report Date —

BCRX BIOCRYST PHARMACEUTICALS 1.5%

Value $4.035M Shares 500,000 Share Price $8.07 * Est. Cost/Share $6.72 Unrealized @ Report Date +15.8%

— ZAFGEN INC 1.3%

Value $3.713M Shares 750,000 Share Price $4.95 Est. Cost/Share $11.49 Unrealized @ Report Date —

— BIODELIVERY SCIENCES INTL IN 1.3%

Value $3.7M Shares 1,000,000 Share Price $3.70 Est. Cost/Share $2.94 Unrealized @ Report Date —

— MOMENTA PHARMACEUTICALS INC 1.3%

Value $3.588M Shares 325,000 Share Price $11.04 Est. Cost/Share $11.04 Unrealized @ Report Date —

— GLOBAL BLOOD THERAPEUTICS IN 1.3%

Value $3.489M Shares 85,000 Share Price $41.05 Est. Cost/Share $41.55 Unrealized @ Report Date —

— SAGE THERAPEUTICS INC 1.0%

Value $2.874M Shares 30,000 Share Price $95.80 Est. Cost/Share $141.26 Unrealized @ Report Date —

ALNY ALNYLAM PHARMACEUTICALS INC 0.9%

Value $2.552M Shares 35,000 Share Price $72.91 * Est. Cost/Share $99.19 Unrealized @ Report Date -22.5%

ARVN ARVINAS INC 0.8%

Value $2.249M Shares 175,000 Share Price $12.85 * Est. Cost/Share $16.46 Unrealized @ Report Date -3.6%

ACAD ACADIA PHARMACEUTICALS INC 0.7%

Value $2.021M Shares 125,000 Share Price $16.17 * Est. Cost/Share $25.20 Unrealized @ Report Date -22.9%

UROV UROVANT SCIENCES LTD 0.7%

Value $1.977M Shares 300,000 Share Price $6.59 Est. Cost/Share $12.00 Unrealized @ Report Date —

— CATALYST BIOSCIENCES INC 0.6%

Value $1.578M Shares 200,000 Share Price $7.89 Est. Cost/Share $25.80 Unrealized @ Report Date —

— GENOCEA BIOSCIENCES INC 0.4%

Value $1.011M Shares 3,525,000 Share Price $0.29 Est. Cost/Share $0.86 Unrealized @ Report Date —

— INTRA CELLULAR THERAPIES INC 0.3%

Value $904K Shares 79,400 Share Price $11.39 Est. Cost/Share — Unrealized @ Report Date —

— PROTEOSTASIS THERAPEUTICS IN 0.2%

Value $616K Shares 190,000 Share Price $3.24 Est. Cost/Share $3.24 Unrealized @ Report Date —

— SAGE THERAPEUTICS INC 0.1%

Value $316K Shares 3,300 Share Price $95.76 Est. Cost/Share $141.26 Unrealized @ Report Date —

— MOTUS GI HLDGS INC 0.1%

Value $311K Shares 100,000 Share Price $3.11 Est. Cost/Share $4.48 Unrealized @ Report Date —

MDGL MADRIGAL PHARMACEUTICALS INC 0.0%

Value $101K Shares 900 Share Price $112.22 * Est. Cost/Share $175.60 Unrealized @ Report Date -11.9%

Ticker	Issuer	Shares	Value	%	Share Price	Est. Cost/Share	Unrealized @ Report Date	Class	CUSIP
XBI	SPDR SERIES TRUST	750,000	$53.81M	19.5%	$71.75	—	—	Call	78464A870
—	MIRATI THERAPEUTICS INC	400,000	$16.97M	6.2%	$42.42	$33.00	—	COM	60468T105
—	DICERNA PHARMACEUTICALS INC	1,250,000	$13.36M	4.8%	$10.69	$11.55	—	COM	253031108
VRTX	VERTEX PHARMACEUTICALS INC	80,000	$13.26M	4.8%	$165.71 *	$173.27	0.0%	COM	92532F100
—	IMMUNOMEDICS INC	800,000	$11.42M	4.1%	$14.27	$8.35	—	COM	452907108
—	IMMUNOMEDICS INC	800,000	$11.42M	4.1%	$14.27	$8.35	—	Put	452907108
—	RETROPHIN INC	500,000	$11.31M	4.1%	$22.63	$26.90	—	COM	761299106
—	BIOHAVEN PHARMACTL HLDG CO L	275,000	$10.17M	3.7%	$36.98	$37.40	—	COM	G11196105
ANAB	ANAPTYSBIO INC	140,000	$8.931M	3.2%	$63.79 *	$80.01	-7.1%	COM	032724106
RCKT	ROCKET PHARMACEUTICALS INC	600,000	$8.892M	3.2%	$14.82 *	$16.85	-1.5%	COM	77313F106
IOVA	IOVANCE BIOTHERAPEUTICS INC	1,000,000	$8.85M	3.2%	$8.85 *	$9.64	0.0%	COM	462260100
KALV	KALVISTA PHARMACEUTICALS INC	425,000	$8.394M	3.0%	$19.75	$16.62	+21.0%	COM	483497103
ASND	ASCENDIS PHARMA A S	125,000	$7.831M	2.8%	$62.65	$49.12	—	SPONSORED ADR	04351P101
SRPT	SAREPTA THERAPEUTICS INC	70,000	$7.639M	2.8%	$109.13 *	$78.35	+59.6%	COM	803607100
—	OBSEVA SA	550,000	$6.963M	2.5%	$12.66	$11.87	—	COM	H5861P103
—	AUDENTES THERAPEUTICS INC	300,000	$6.396M	2.3%	$21.32	$21.32	—	COM	05070R104
FOLD	AMICUS THERAPEUTICS INC	650,000	$6.227M	2.3%	$9.58 *	$10.99	0.0%	COM	03152W109
—	TRICIDA INC	250,000	$5.895M	2.1%	$23.58	$30.07	—	COM	89610F101
FXF	INVESCO CURNCYSHS SWISS FRAN	55,200	$5.237M	1.9%	$94.87	$95.31	—	SWISS FRANC	46138R108
—	ORCHARD THERAPEUTICS PLC	300,000	$4.719M	1.7%	$15.73	$15.73	—	ADS	68570P101
VRAYQ	VIEWRAY INC	750,000	$4.553M	1.7%	$6.07 *	$6.99	+7.3%	COM	92672L107
—	KADMON HLDGS INC	2,000,000	$4.16M	1.5%	$2.08	$3.85	—	COM	48283N106
—	GLOBAL BLOOD THERAPEUTICS IN	100,000	$4.105M	1.5%	$41.05	$41.55	—	COM	37890U108
BCRX	BIOCRYST PHARMACEUTICALS	500,000	$4.035M	1.5%	$8.07 *	$6.72	+15.8%	COM	09058V103
—	ZAFGEN INC	750,000	$3.713M	1.3%	$4.95	$11.49	—	COM	98885E103
—	BIODELIVERY SCIENCES INTL IN	1,000,000	$3.7M	1.3%	$3.70	$2.94	—	COM	09060J106
—	MOMENTA PHARMACEUTICALS INC	325,000	$3.588M	1.3%	$11.04	$11.04	—	COM	60877T100
—	GLOBAL BLOOD THERAPEUTICS IN	85,000	$3.489M	1.3%	$41.05	$41.55	—	Put	37890U108
—	SAGE THERAPEUTICS INC	30,000	$2.874M	1.0%	$95.80	$141.26	—	Call	78667J108
ALNY	ALNYLAM PHARMACEUTICALS INC	35,000	$2.552M	0.9%	$72.91 *	$99.19	-22.5%	COM	02043Q107
ARVN	ARVINAS INC	175,000	$2.249M	0.8%	$12.85 *	$16.46	-3.6%	COM	04335A105
ACAD	ACADIA PHARMACEUTICALS INC	125,000	$2.021M	0.7%	$16.17 *	$25.20	-22.9%	COM	004225108
UROV	UROVANT SCIENCES LTD	300,000	$1.977M	0.7%	$6.59	$12.00	—	SHS	G9381B108
—	CATALYST BIOSCIENCES INC	200,000	$1.578M	0.6%	$7.89	$25.80	—	COM NEW	14888D208
—	GENOCEA BIOSCIENCES INC	3,525,000	$1.011M	0.4%	$0.29	$0.86	—	COM	372427104
—	INTRA CELLULAR THERAPIES INC	79,400	$904K	0.3%	$11.39	—	—	Call	46116X101
—	PROTEOSTASIS THERAPEUTICS IN	190,000	$616K	0.2%	$3.24	$3.24	—	COM	74373B109
—	SAGE THERAPEUTICS INC	3,300	$316K	0.1%	$95.76	$141.26	—	COM	78667J108
—	MOTUS GI HLDGS INC	100,000	$311K	0.1%	$3.11	$4.48	—	COM	62014P108
MDGL	MADRIGAL PHARMACEUTICALS INC	900	$101K	0.0%	$112.22 *	$175.60	-11.9%	COM	558868105