Ghost Tree Capital, LLC Hedge Fund

CIK: 0001595851 · Show all filings

Period: Q3 2019 (← Previous) (Next →)

Filing Date: Apr 9, 2020

Total Value: $393M (100.0% shares, 0.0% debt)

Holdings (44)

XBI SPDR SERIES TRUST 7.8%

Value $30.58M Shares 401,000 Est. Cost — Unrealized —

SPY SPDR S&P 500 ETF TR 7.6%

Value $29.68M Shares 100,000 Est. Cost — Unrealized —

— BLUEPRINT MEDICINES CORP 6.1%

Value $23.88M Shares 325,000 Est. Cost $85.19 Unrealized —

— MIRATI THERAPEUTICS INC 5.5%

Value $21.43M Shares 275,000 Est. Cost $71.66 Unrealized —

SRPT SAREPTA THERAPEUTICS INC 4.2%

Value $16.57M Shares 220,000 Est. Cost $121.54 Unrealized -2.8%

— IMMUNOMEDICS INC 4.1%

Value $15.93M Shares 1,201,000 Est. Cost $9.20 Unrealized —

— SAGE THERAPEUTICS INC 3.9%

Value $15.43M Shares 110,000 Est. Cost $145.19 Unrealized —

SRPT SAREPTA THERAPEUTICS INC 3.8%

Value $15.06M Shares 200,000 Est. Cost $121.54 Unrealized -2.8%

— BIOHAVEN PHARMACTL HLDG CO L 3.7%

Value $14.6M Shares 350,000 Est. Cost $42.31 Unrealized —

ASND ASCENDIS PHARMA A S 3.7%

Value $14.45M Shares 150,000 Est. Cost $95.44 Unrealized —

QQQ INVESCO QQQ TR 3.6%

Value $14.16M Shares 75,000 Est. Cost — Unrealized —

FOLD AMICUS THERAPEUTICS INC 3.5%

Value $13.67M Shares 1,705,000 Est. Cost $11.59 Unrealized -6.3%

AXSM AXSOME THERAPEUTICS INC 3.5%

Value $13.66M Shares 675,000 Est. Cost $16.12 Unrealized +59.4%

FXB INVESCO CURNCYSHS BRIT PND S 3.2%

Value $12.59M Shares 105,600 Est. Cost $119.25 Unrealized —

BMRN BIOMARIN PHARMACEUTICAL INC 3.2%

Value $12.47M Shares 185,000 Est. Cost $77.02 Unrealized 0.0%

— IMMUNOMEDICS INC 2.4%

Value $9.614M Shares 725,000 Est. Cost $9.20 Unrealized —

PCRX PACIRA PHARMACEUTICALS INC 2.4%

Value $9.518M Shares 250,000 Est. Cost $39.91 Unrealized 0.0%

IOVA IOVANCE BIOTHERAPEUTICS INC 2.3%

Value $9.1M Shares 500,000 Est. Cost $18.38 Unrealized +20.3%

— ADVERUM BIOTECHNOLOGIES INC 2.0%

Value $7.903M Shares 1,450,000 Est. Cost $5.45 Unrealized —

RCKT ROCKET PHARMACEUTICALS INC 1.9%

Value $7.281M Shares 625,000 Est. Cost $15.68 Unrealized -20.9%

— ATHENEX INC 1.6%

Value $6.356M Shares 522,500 Est. Cost $12.16 Unrealized —

ARGX ARGENX SE 1.5%

Value $5.698M Shares 50,000 Est. Cost $141.58 Unrealized —

FATE FATE THERAPEUTICS INC 1.4%

Value $5.436M Shares 350,000 Est. Cost $19.17 Unrealized 0.0%

— TURNING POINT THERAPEUTICS I 1.2%

Value $4.7M Shares 125,000 Est. Cost $37.60 Unrealized —

— MOMENTA PHARMACEUTICALS INC 1.2%

Value $4.536M Shares 350,000 Est. Cost $12.26 Unrealized —

— KADMON HLDGS INC 1.1%

Value $4.41M Shares 1,750,000 Est. Cost $3.79 Unrealized —

FXF INVESCO CURNCYSHS SWISS FRAN 1.1%

Value $4.399M Shares 47,500 Est. Cost $94.55 Unrealized —

MIST MILESTONE PHARMACEUTICALS IN 1.1%

Value $4.383M Shares 235,000 Est. Cost $20.62 Unrealized -4.4%

— AERIE PHARMACEUTICALS INC 1.1%

Value $4.325M Shares 225,000 Est. Cost $19.22 Unrealized —

BCRX BIOCRYST PHARMACEUTICALS 1.1%

Value $4.298M Shares 1,500,000 Est. Cost $6.16 Unrealized -49.5%

— HOMOLOGY MEDICINES INC 1.0%

Value $4.073M Shares 225,000 Est. Cost $18.92 Unrealized —

— REATA PHARMACEUTICALS INC 1.0%

Value $4.015M Shares 50,000 Est. Cost $80.30 Unrealized —

ARVN ARVINAS INC 1.0%

Value $3.987M Shares 185,000 Est. Cost $17.47 Unrealized +40.4%

KALV KALVISTA PHARMACEUTICALS INC 0.9%

Value $3.654M Shares 315,000 Est. Cost $16.59 Unrealized -2.6%

— DICERNA PHARMACEUTICALS INC 0.9%

Value $3.375M Shares 235,000 Est. Cost $15.75 Unrealized —

PTGX PROTAGONIST THERAPEUTICS INC 0.8%

Value $3.003M Shares 250,000 Est. Cost $9.58 Unrealized +31.5%

— ORCHARD THERAPEUTICS PLC 0.7%

Value $2.886M Shares 242,950 Est. Cost $15.73 Unrealized —

VRAYQ VIEWRAY INC 0.6%

Value $2.393M Shares 825,000 Est. Cost $6.89 Unrealized -14.0%

— CYMABAY THERAPEUTICS INC 0.6%

Value $2.253M Shares 440,000 Est. Cost $11.75 Unrealized —

— AVROBIO INC 0.6%

Value $2.192M Shares 155,253 Est. Cost $14.12 Unrealized —

— CHIASMA INC 0.5%

Value $1.893M Shares 382,500 Est. Cost $5.20 Unrealized —

— EPIZYME INC 0.3%

Value $1.362M Shares 132,000 Est. Cost $12.39 Unrealized —

— SOLID BIOSCIENCES INC 0.3%

Value $1.034M Shares 100,000 Est. Cost $9.20 Unrealized —

— DERMIRA INC 0.1%

Value $272K Shares 42,500 Est. Cost $6.40 Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
XBI	SPDR SERIES TRUST	401,000	$30.58M	7.8%	—	—	Put	78464A870
SPY	SPDR S&P 500 ETF TR	100,000	$29.68M	7.6%	—	—	Put	78462F103
—	BLUEPRINT MEDICINES CORP	325,000	$23.88M	6.1%	$85.19	—	COM	09627Y109
—	MIRATI THERAPEUTICS INC	275,000	$21.43M	5.5%	$71.66	—	COM	60468T105
SRPT	SAREPTA THERAPEUTICS INC	220,000	$16.57M	4.2%	$121.54	-2.8%	COM	803607100
—	IMMUNOMEDICS INC	1,201,000	$15.93M	4.1%	$9.20	—	Call	452907108
—	SAGE THERAPEUTICS INC	110,000	$15.43M	3.9%	$145.19	—	COM	78667J108
SRPT	SAREPTA THERAPEUTICS INC	200,000	$15.06M	3.8%	$121.54	-2.8%	Put	803607100
—	BIOHAVEN PHARMACTL HLDG CO L	350,000	$14.6M	3.7%	$42.31	—	COM	G11196105
ASND	ASCENDIS PHARMA A S	150,000	$14.45M	3.7%	$95.44	—	SPONSORED ADR	04351P101
QQQ	INVESCO QQQ TR	75,000	$14.16M	3.6%	—	—	Put	46090E103
FOLD	AMICUS THERAPEUTICS INC	1,705,000	$13.67M	3.5%	$11.59	-6.3%	COM	03152W109
AXSM	AXSOME THERAPEUTICS INC	675,000	$13.66M	3.5%	$16.12	+59.4%	COM	05464T104
FXB	INVESCO CURNCYSHS BRIT PND S	105,600	$12.59M	3.2%	$119.25	—	BRIT POUN STRL	46138M109
BMRN	BIOMARIN PHARMACEUTICAL INC	185,000	$12.47M	3.2%	$77.02	0.0%	COM	09061G101
—	IMMUNOMEDICS INC	725,000	$9.614M	2.4%	$9.20	—	COM	452907108
PCRX	PACIRA PHARMACEUTICALS INC	250,000	$9.518M	2.4%	$39.91	0.0%	COM	695127100
IOVA	IOVANCE BIOTHERAPEUTICS INC	500,000	$9.1M	2.3%	$18.38	+20.3%	COM	462260100
—	ADVERUM BIOTECHNOLOGIES INC	1,450,000	$7.903M	2.0%	$5.45	—	COM	00773U108
RCKT	ROCKET PHARMACEUTICALS INC	625,000	$7.281M	1.9%	$15.68	-20.9%	COM	77313F106
—	ATHENEX INC	522,500	$6.356M	1.6%	$12.16	—	COM	04685N103
ARGX	ARGENX SE	50,000	$5.698M	1.5%	$141.58	—	SPONSORED ADR	04016X101
FATE	FATE THERAPEUTICS INC	350,000	$5.436M	1.4%	$19.17	0.0%	COM	31189P102
—	TURNING POINT THERAPEUTICS I	125,000	$4.7M	1.2%	$37.60	—	COM	90041T108
—	MOMENTA PHARMACEUTICALS INC	350,000	$4.536M	1.2%	$12.26	—	COM	60877T100
—	KADMON HLDGS INC	1,750,000	$4.41M	1.1%	$3.79	—	COM	48283N106
FXF	INVESCO CURNCYSHS SWISS FRAN	47,500	$4.399M	1.1%	$94.55	—	SWISS FRANC	46138R108
MIST	MILESTONE PHARMACEUTICALS IN	235,000	$4.383M	1.1%	$20.62	-4.4%	COM	59935V107
—	AERIE PHARMACEUTICALS INC	225,000	$4.325M	1.1%	$19.22	—	COM	00771V108
BCRX	BIOCRYST PHARMACEUTICALS	1,500,000	$4.298M	1.1%	$6.16	-49.5%	COM	09058V103
—	HOMOLOGY MEDICINES INC	225,000	$4.073M	1.0%	$18.92	—	COM	438083107
—	REATA PHARMACEUTICALS INC	50,000	$4.015M	1.0%	$80.30	—	CL A	75615P103
ARVN	ARVINAS INC	185,000	$3.987M	1.0%	$17.47	+40.4%	COM	04335A105
KALV	KALVISTA PHARMACEUTICALS INC	315,000	$3.654M	0.9%	$16.59	-2.6%	COM	483497103
—	DICERNA PHARMACEUTICALS INC	235,000	$3.375M	0.9%	$15.75	—	COM	253031108
PTGX	PROTAGONIST THERAPEUTICS INC	250,000	$3.003M	0.8%	$9.58	+31.5%	COM	74366E102
—	ORCHARD THERAPEUTICS PLC	242,950	$2.886M	0.7%	$15.73	—	ADS	68570P101
VRAYQ	VIEWRAY INC	825,000	$2.393M	0.6%	$6.89	-14.0%	COM	92672L107
—	CYMABAY THERAPEUTICS INC	440,000	$2.253M	0.6%	$11.75	—	COM	23257D103
—	AVROBIO INC	155,253	$2.192M	0.6%	$14.12	—	COM	05455M100
—	CHIASMA INC	382,500	$1.893M	0.5%	$5.20	—	COM	16706W102
—	EPIZYME INC	132,000	$1.362M	0.3%	$12.39	—	COM	29428V104
—	SOLID BIOSCIENCES INC	100,000	$1.034M	0.3%	$9.20	—	COM	83422E105
—	DERMIRA INC	42,500	$272K	0.1%	$6.40	—	COM	24983L104