Ghost Tree Capital, LLC Hedge Fund

CIK: 0001595851 · Show all filings

Period: Q2 2019 (← Previous) (Next →)

Filing Date: Apr 9, 2020

Total Value: $482M (100.0% shares, 0.0% debt)

Holdings (43)

SRPT SAREPTA THERAPEUTICS INC 9.1%

Value $44.07M Shares 290,000 Est. Cost $121.54 Unrealized 0.0%

XBI SPDR SERIES TRUST 9.1%

Value $43.85M Shares 500,000 Est. Cost — Unrealized —

QQQ INVESCO QQQ TR 7.7%

Value $37.35M Shares 200,000 Est. Cost — Unrealized —

— BLUEPRINT MEDICINES CORP 7.3%

Value $35.37M Shares 375,000 Est. Cost $85.19 Unrealized —

— MIRATI THERAPEUTICS INC 7.2%

Value $34.51M Shares 335,000 Est. Cost $71.66 Unrealized —

ASND ASCENDIS PHARMA A S 5.4%

Value $25.91M Shares 225,000 Est. Cost $95.44 Unrealized —

AXSM AXSOME THERAPEUTICS INC 4.5%

Value $21.89M Shares 850,000 Est. Cost $16.12 Unrealized +24.3%

ACAD ACADIA PHARMACEUTICALS INC 4.2%

Value $20.05M Shares 750,000 Est. Cost $23.61 Unrealized +8.2%

FOLD AMICUS THERAPEUTICS INC 3.8%

Value $18.1M Shares 1,450,000 Est. Cost $11.72 Unrealized +8.3%

— GLOBAL BLOOD THERAPEUTICS IN 3.3%

Value $15.78M Shares 300,000 Est. Cost $49.14 Unrealized —

ARGX ARGENX SE 2.9%

Value $14.16M Shares 100,000 Est. Cost $141.58 Unrealized —

— IMMUNOMEDICS INC 2.3%

Value $11.1M Shares 800,000 Est. Cost $8.35 Unrealized —

ALNY ALNYLAM PHARMACEUTICALS INC 2.3%

Value $10.88M Shares 150,000 Est. Cost $87.26 Unrealized -12.1%

BCRX BIOCRYST PHARMACEUTICALS 2.0%

Value $9.475M Shares 2,500,000 Est. Cost $6.16 Unrealized -2.3%

— RA PHARMACEUTICALS INC 1.9%

Value $9.021M Shares 300,000 Est. Cost $22.40 Unrealized —

FXF INVESCO CURNCYSHS SWISS FRAN 1.8%

Value $8.751M Shares 92,200 Est. Cost $94.55 Unrealized —

— IMMUNOMEDICS INC 1.7%

Value $8.322M Shares 600,000 Est. Cost $8.35 Unrealized —

— CYMABAY THERAPEUTICS INC 1.5%

Value $7.16M Shares 1,000,000 Est. Cost $11.75 Unrealized —

RCKT ROCKET PHARMACEUTICALS INC 1.4%

Value $6.9M Shares 460,000 Est. Cost $16.85 Unrealized +3.5%

KALV KALVISTA PHARMACEUTICALS INC 1.4%

Value $6.645M Shares 300,000 Est. Cost $16.62 Unrealized +41.1%

VRAYQ VIEWRAY INC 1.4%

Value $6.608M Shares 750,000 Est. Cost $6.99 Unrealized +16.2%

MIST MILESTONE PHARMACEUTICALS IN 1.4%

Value $6.516M Shares 240,000 Est. Cost $20.62 Unrealized 0.0%

PFE PFIZER INC 1.3%

Value $6.498M Shares 150,000 Est. Cost — Unrealized —

— MOMENTA PHARMACEUTICALS INC 1.3%

Value $6.225M Shares 500,000 Est. Cost $12.26 Unrealized —

— ZYMEWORKS INC 1.3%

Value $6.05M Shares 275,000 Est. Cost $22.00 Unrealized —

— EPIZYME INC 1.2%

Value $5.836M Shares 465,000 Est. Cost $12.39 Unrealized —

— SAGE THERAPEUTICS INC 1.1%

Value $5.493M Shares 30,000 Est. Cost $158.27 Unrealized —

— SPARK THERAPEUTICS INC 1.1%

Value $5.119M Shares 50,000 Est. Cost $102.38 Unrealized —

ARVN ARVINAS INC 1.0%

Value $4.948M Shares 225,000 Est. Cost $17.47 Unrealized +20.3%

— BIOHAVEN PHARMACTL HLDG CO L 0.9%

Value $4.379M Shares 100,000 Est. Cost $43.79 Unrealized —

— KADMON HLDGS INC 0.9%

Value $4.326M Shares 2,100,000 Est. Cost $3.79 Unrealized —

CHRS COHERUS BIOSCIENCES INC 0.8%

Value $3.868M Shares 175,000 Est. Cost $13.34 Unrealized +30.2%

— DICERNA PHARMACEUTICALS INC 0.8%

Value $3.701M Shares 235,000 Est. Cost $15.75 Unrealized —

IOVA IOVANCE BIOTHERAPEUTICS INC 0.8%

Value $3.678M Shares 150,000 Est. Cost $9.65 Unrealized +56.0%

— ORCHARD THERAPEUTICS PLC 0.7%

Value $3.399M Shares 242,950 Est. Cost $15.73 Unrealized —

— CHIASMA INC 0.6%

Value $2.988M Shares 400,000 Est. Cost $5.20 Unrealized —

QURE UNIQURE NV 0.6%

Value $2.735M Shares 35,000 Est. Cost $63.72 Unrealized 0.0%

— HOMOLOGY MEDICINES INC 0.5%

Value $2.446M Shares 125,000 Est. Cost $19.57 Unrealized —

PTGX PROTAGONIST THERAPEUTICS INC 0.5%

Value $2.422M Shares 200,000 Est. Cost $8.83 Unrealized +25.3%

— ODONATE THERAPEUTICS INC 0.5%

Value $2.385M Shares 65,000 Est. Cost $36.69 Unrealized —

— ARQULE INC 0.5%

Value $2.202M Shares 200,000 Est. Cost $11.01 Unrealized —

— SOLID BIOSCIENCES INC 0.1%

Value $575K Shares 100,000 Est. Cost $9.20 Unrealized —

— ALLAKOS INC 0.1%

Value $455K Shares 10,500 Est. Cost $43.33 Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
SRPT	SAREPTA THERAPEUTICS INC	290,000	$44.07M	9.1%	$121.54	0.0%	COM	803607100
XBI	SPDR SERIES TRUST	500,000	$43.85M	9.1%	—	—	Put	78464A870
QQQ	INVESCO QQQ TR	200,000	$37.35M	7.7%	—	—	Put	46090E103
—	BLUEPRINT MEDICINES CORP	375,000	$35.37M	7.3%	$85.19	—	COM	09627Y109
—	MIRATI THERAPEUTICS INC	335,000	$34.51M	7.2%	$71.66	—	COM	60468T105
ASND	ASCENDIS PHARMA A S	225,000	$25.91M	5.4%	$95.44	—	SPONSORED ADR	04351P101
AXSM	AXSOME THERAPEUTICS INC	850,000	$21.89M	4.5%	$16.12	+24.3%	COM	05464T104
ACAD	ACADIA PHARMACEUTICALS INC	750,000	$20.05M	4.2%	$23.61	+8.2%	COM	004225108
FOLD	AMICUS THERAPEUTICS INC	1,450,000	$18.1M	3.8%	$11.72	+8.3%	COM	03152W109
—	GLOBAL BLOOD THERAPEUTICS IN	300,000	$15.78M	3.3%	$49.14	—	COM	37890U108
ARGX	ARGENX SE	100,000	$14.16M	2.9%	$141.58	—	SPONSORED ADR	04016X101
—	IMMUNOMEDICS INC	800,000	$11.1M	2.3%	$8.35	—	Call	452907108
ALNY	ALNYLAM PHARMACEUTICALS INC	150,000	$10.88M	2.3%	$87.26	-12.1%	COM	02043Q107
BCRX	BIOCRYST PHARMACEUTICALS	2,500,000	$9.475M	2.0%	$6.16	-2.3%	COM	09058V103
—	RA PHARMACEUTICALS INC	300,000	$9.021M	1.9%	$22.40	—	COM	74933V108
FXF	INVESCO CURNCYSHS SWISS FRAN	92,200	$8.751M	1.8%	$94.55	—	SWISS FRANC	46138R108
—	IMMUNOMEDICS INC	600,000	$8.322M	1.7%	$8.35	—	COM	452907108
—	CYMABAY THERAPEUTICS INC	1,000,000	$7.16M	1.5%	$11.75	—	COM	23257D103
RCKT	ROCKET PHARMACEUTICALS INC	460,000	$6.9M	1.4%	$16.85	+3.5%	COM	77313F106
KALV	KALVISTA PHARMACEUTICALS INC	300,000	$6.645M	1.4%	$16.62	+41.1%	COM	483497103
VRAYQ	VIEWRAY INC	750,000	$6.608M	1.4%	$6.99	+16.2%	COM	92672L107
MIST	MILESTONE PHARMACEUTICALS IN	240,000	$6.516M	1.4%	$20.62	0.0%	COM	59935V107
PFE	PFIZER INC	150,000	$6.498M	1.3%	—	—	Put	717081103
—	MOMENTA PHARMACEUTICALS INC	500,000	$6.225M	1.3%	$12.26	—	COM	60877T100
—	ZYMEWORKS INC	275,000	$6.05M	1.3%	$22.00	—	COM	98985W102
—	EPIZYME INC	465,000	$5.836M	1.2%	$12.39	—	COM	29428V104
—	SAGE THERAPEUTICS INC	30,000	$5.493M	1.1%	$158.27	—	COM	78667J108
—	SPARK THERAPEUTICS INC	50,000	$5.119M	1.1%	$102.38	—	COM	84652J103
ARVN	ARVINAS INC	225,000	$4.948M	1.0%	$17.47	+20.3%	COM	04335A105
—	BIOHAVEN PHARMACTL HLDG CO L	100,000	$4.379M	0.9%	$43.79	—	COM	G11196105
—	KADMON HLDGS INC	2,100,000	$4.326M	0.9%	$3.79	—	COM	48283N106
CHRS	COHERUS BIOSCIENCES INC	175,000	$3.868M	0.8%	$13.34	+30.2%	COM	19249H103
—	DICERNA PHARMACEUTICALS INC	235,000	$3.701M	0.8%	$15.75	—	COM	253031108
IOVA	IOVANCE BIOTHERAPEUTICS INC	150,000	$3.678M	0.8%	$9.65	+56.0%	COM	462260100
—	ORCHARD THERAPEUTICS PLC	242,950	$3.399M	0.7%	$15.73	—	ADS	68570P101
—	CHIASMA INC	400,000	$2.988M	0.6%	$5.20	—	COM	16706W102
QURE	UNIQURE NV	35,000	$2.735M	0.6%	$63.72	0.0%	SHS	N90064101
—	HOMOLOGY MEDICINES INC	125,000	$2.446M	0.5%	$19.57	—	COM	438083107
PTGX	PROTAGONIST THERAPEUTICS INC	200,000	$2.422M	0.5%	$8.83	+25.3%	COM	74366E102
—	ODONATE THERAPEUTICS INC	65,000	$2.385M	0.5%	$36.69	—	COM	676079106
—	ARQULE INC	200,000	$2.202M	0.5%	$11.01	—	COM	04269E107
—	SOLID BIOSCIENCES INC	100,000	$575K	0.1%	$9.20	—	COM	83422E105
—	ALLAKOS INC	10,500	$455K	0.1%	$43.33	—	COM	01671P100