Ghost Tree Capital, LLC Hedge Fund

CIK: 0001595851 · Show all filings

Period: Q3 2021 (← Previous) (Next →)

Filing Date: Nov 15, 2021

Total Value: $342M (100.0% shares, 0.0% debt)

Holdings (60)

IWM ISHARES TR 6.4%
Value $21.88M Shares 100,000 Share Price $218.75 Est. Cost/Share — Unrealized @ Report Date —
ASND ASCENDIS PHARMA A/S 5.6%
Value $19.13M Shares 120,000 Share Price $159.39 Est. Cost/Share $130.02 Unrealized @ Report Date —
IOVA IOVANCE BIOTHERAPEUTICS INC 5.0%
Value $17.26M Shares 700,000 Share Price $24.66 * Est. Cost/Share $24.32 Unrealized @ Report Date -3.1%
CLDX CELLDEX THERAPEUTICS INC NEW 4.0%
Value $13.77M Shares 255,000 Share Price $53.99 * Est. Cost/Share $23.51 Unrealized @ Report Date +99.6%
COGT COGENT BIOSCIENCES INC 3.7%
Value $12.62M Shares 1,500,000 Share Price $8.41 * Est. Cost/Share $10.56 Unrealized @ Report Date -27.5%
ARVN ARVINAS INC 3.6%
Value $12.33M Shares 150,000 Share Price $82.18 * Est. Cost/Share $28.07 Unrealized @ Report Date +214.8%
XENE XENON PHARMACEUTICALS INC 3.5%
Value $12.07M Shares 790,000 Share Price $15.28 * Est. Cost/Share $13.60 Unrealized @ Report Date +27.8%
— IVERIC BIO INC 3.4%
Value $11.77M Shares 725,000 Share Price $16.24 Est. Cost/Share $7.44 Unrealized @ Report Date —
SNDX SYNDAX PHARMACEUTICALS INC 3.2%
Value $10.99M Shares 575,000 Share Price $19.11 * Est. Cost/Share $18.21 Unrealized @ Report Date -8.5%
— MIRATI THERAPEUTICS INC 3.1%
Value $10.62M Shares 60,000 Share Price $176.92 Est. Cost/Share $98.34 Unrealized @ Report Date —
RCKT ROCKET PHARMACEUTICALS INC 3.1%
Value $10.46M Shares 350,000 Share Price $29.89 * Est. Cost/Share $30.51 Unrealized @ Report Date +19.3%
— ALLAKOS INC 2.6%
Value $8.999M Shares 85,000 Share Price $105.87 Est. Cost/Share $105.87 Unrealized @ Report Date —
GHRS GH RESEARCH PLC 2.6%
Value $8.824M Shares 400,000 Share Price $22.06 * Est. Cost/Share $20.35 Unrealized @ Report Date 0.0%
KURA KURA ONCOLOGY INC 2.3%
Value $7.96M Shares 425,000 Share Price $18.73 Est. Cost/Share $28.09 Unrealized @ Report Date -32.9%
— RAPT THERAPEUTICS INC 2.3%
Value $7.763M Shares 250,000 Share Price $31.05 Est. Cost/Share $31.79 Unrealized @ Report Date —
— LEAP THERAPEUTICS INC 1.9%
Value $6.617M Shares 1,650,000 Share Price $4.01 Est. Cost/Share $4.01 Unrealized @ Report Date —
APLS APELLIS PHARMACEUTICALS INC 1.9%
Value $6.592M Shares 200,000 Share Price $32.96 * Est. Cost/Share $56.19 Unrealized @ Report Date 0.0%
BYSI BEYONDSPRING INC 1.8%
Value $6.304M Shares 400,000 Share Price $15.76 Est. Cost/Share — Unrealized @ Report Date —
ALDX ALDEYRA THERAPEUTICS INC 1.8%
Value $6.146M Shares 700,000 Share Price $8.78 * Est. Cost/Share $4.92 Unrealized @ Report Date +86.4%
VRDN VIRIDIAN THERAPEUTICS INC 1.7%
Value $5.758M Shares 350,000 Share Price $16.45 * Est. Cost/Share $18.49 Unrealized @ Report Date -20.7%
— VISTAGEN THERAPEUTICS INC 1.6%
Value $5.48M Shares 2,000,000 Share Price $2.74 Est. Cost/Share $2.02 Unrealized @ Report Date —
AVIR ATEA PHARMACEUTICALS INC 1.5%
Value $5.259M Shares 150,000 Share Price $35.06 * Est. Cost/Share $27.74 Unrealized @ Report Date 0.0%
RLMD RELMADA THERAPEUTICS INC 1.5%
Value $5.242M Shares 200,000 Share Price $26.21 * Est. Cost/Share $26.77 Unrealized @ Report Date 0.0%
ACRS ACLARIS THERAPEUTICS INC 1.4%
Value $4.95M Shares 275,000 Share Price $18.00 * Est. Cost/Share $5.29 Unrealized @ Report Date +202.9%
APLS APELLIS PHARMACEUTICALS INC 1.4%
Value $4.944M Shares 150,000 Share Price $32.96 * Est. Cost/Share $56.19 Unrealized @ Report Date 0.0%
MLTX HELIX ACQUISITION CORP 1.4%
Value $4.943M Shares 500,000 Share Price $9.89 Est. Cost/Share $11.37 Unrealized @ Report Date —
— CTI BIOPHARMA CORP 1.4%
Value $4.72M Shares 1,600,000 Share Price $2.95 Est. Cost/Share $2.84 Unrealized @ Report Date —
— PRAXIS PRECISION MEDICINES I 1.4%
Value $4.623M Shares 250,000 Share Price $18.49 Est. Cost/Share $18.49 Unrealized @ Report Date —
— SIERRA ONCOLOGY INC 1.3%
Value $4.384M Shares 200,000 Share Price $21.92 Est. Cost/Share $16.03 Unrealized @ Report Date —
ZNTL ZENTALIS PHARMACEUTICALS INC 1.3%
Value $4.332M Shares 65,000 Share Price $66.65 * Est. Cost/Share $57.69 Unrealized @ Report Date 0.0%
— SATSUMA PHARMACEUTICALS INC 1.2%
Value $4.214M Shares 904,225 Share Price $4.66 Est. Cost/Share $10.24 Unrealized @ Report Date —
BCYC BICYCLE THERAPEUTICS PLC 1.2%
Value $4.159M Shares 100,000 Share Price $41.59 Est. Cost/Share $30.00 Unrealized @ Report Date —
— CATALYST BIOSCIENCES INC 1.2%
Value $4.11M Shares 1,000,000 Share Price $4.11 Est. Cost/Share $5.04 Unrealized @ Report Date —
— VERONA PHARMA PLC 1.2%
Value $4.11M Shares 750,000 Share Price $5.48 Est. Cost/Share $6.53 Unrealized @ Report Date —
— TCR2 THERAPEUTICS INC 1.2%
Value $4.062M Shares 477,323 Share Price $8.51 Est. Cost/Share $8.51 Unrealized @ Report Date —
PCVX VAXCYTE INC 1.2%
Value $4.059M Shares 160,000 Share Price $25.37 * Est. Cost/Share $20.83 Unrealized @ Report Date +16.4%
ALLO ALLOGENE THERAPEUTICS INC 1.1%
Value $3.855M Shares 150,000 Share Price $25.70 * Est. Cost/Share $28.52 Unrealized @ Report Date -16.7%
XENE XENON PHARMACEUTICALS INC 1.1%
Value $3.82M Shares 250,000 Share Price $15.28 * Est. Cost/Share $13.60 Unrealized @ Report Date +27.8%
TARS TARSUS PHARMACEUTICALS INC 1.1%
Value $3.664M Shares 170,000 Share Price $21.55 * Est. Cost/Share $31.23 Unrealized @ Report Date -20.7%
— 9 METERS BIOPHARMA INC 1.0%
Value $3.575M Shares 2,750,000 Share Price $1.30 Est. Cost/Share $1.30 Unrealized @ Report Date —
CRNX CRINETICS PHARMACEUTICALS IN 0.9%
Value $3.158M Shares 150,000 Share Price $21.05 Est. Cost/Share $17.57 Unrealized @ Report Date +19.0%
CMPS COMPASS PATHWAYS PLC 0.9%
Value $2.987M Shares 100,000 Share Price $29.87 Est. Cost/Share $29.87 Unrealized @ Report Date —
FATE FATE THERAPEUTICS INC 0.9%
Value $2.964M Shares 50,000 Share Price $59.28 * Est. Cost/Share $32.72 Unrealized @ Report Date +139.7%
HRMY HARMONY BIOSCIENCES HLDGS IN 0.8%
Value $2.875M Shares 75,000 Share Price $38.33 * Est. Cost/Share $30.00 Unrealized @ Report Date +7.3%
FOLD AMICUS THERAPEUTICS INC 0.7%
Value $2.531M Shares 265,000 Share Price $9.55 * Est. Cost/Share $14.57 Unrealized @ Report Date -29.8%
— BELLUS HEALTH INC NEW 0.7%
Value $2.456M Shares 400,000 Share Price $6.14 Est. Cost/Share $6.14 Unrealized @ Report Date —
IMUX IMMUNIC INC 0.7%
Value $2.345M Shares 265,000 Share Price $8.85 * Est. Cost/Share $16.38 Unrealized @ Report Date -39.9%
LRMR LARIMAR THERAPEUTICS INC 0.7%
Value $2.306M Shares 200,000 Share Price $11.53 * Est. Cost/Share $11.65 Unrealized @ Report Date +3.0%
MRNA MODERNA INC 0.6%
Value $2.04M Shares 5,300 Share Price $384.91 * Est. Cost/Share $225.34 Unrealized @ Report Date +63.7%
ALEC ALECTOR INC 0.5%
Value $1.826M Shares 80,000 Share Price $22.82 * Est. Cost/Share $28.01 Unrealized @ Report Date 0.0%
IMVT IMMUNOVANT INC 0.5%
Value $1.738M Shares 200,000 Share Price $8.69 Est. Cost/Share — Unrealized @ Report Date —
— MERUS N V 0.5%
Value $1.65M Shares 75,000 Share Price $22.00 Est. Cost/Share $21.07 Unrealized @ Report Date —
FULC FULCRUM THERAPEUTICS INC 0.4%
Value $1.411M Shares 50,000 Share Price $28.22 * Est. Cost/Share $18.95 Unrealized @ Report Date 0.0%
— CHIMERIX INC 0.4%
Value $1.238M Shares 200,000 Share Price $6.19 Est. Cost/Share $9.64 Unrealized @ Report Date —
CABA CABALETTA BIO INC 0.4%
Value $1.216M Shares 100,000 Share Price $12.16 * Est. Cost/Share $9.22 Unrealized @ Report Date 0.0%
— OTONOMY INC 0.3%
Value $864K Shares 450,000 Share Price $1.92 Est. Cost/Share $4.29 Unrealized @ Report Date —
— CASI PHARMACEUTICALS INC 0.2%
Value $774K Shares 650,000 Share Price $1.19 Est. Cost/Share $2.40 Unrealized @ Report Date —
BNTX BIONTECH SE 0.2%
Value $546K Shares 2,000 Share Price $273.00 Est. Cost/Share $273.00 Unrealized @ Report Date —
— CODEX DNA INC 0.1%
Value $390K Shares 35,000 Share Price $11.14 Est. Cost/Share $22.00 Unrealized @ Report Date —
— PROVENTION BIO INC 0.1%
Value $320K Shares 50,000 Share Price $6.40 Est. Cost/Share $8.43 Unrealized @ Report Date —