Ghost Tree Capital, LLC Hedge Fund

CIK: 0001595851 · Show all filings

Period: Q4 2021 (← Previous) (Next →)

Filing Date: Feb 16, 2022

Total Value: $279M (100.0% shares, 0.0% debt)

Holdings (46)

ASND ASCENDIS PHARMA A/S 9.2%
Value $25.56M Shares 190,000 Share Price $134.53 Est. Cost/Share $131.68 Unrealized @ Report Date —
APLS APELLIS PHARMACEUTICALS INC 5.5%
Value $15.37M Shares 325,000 Share Price $47.28 * Est. Cost/Share $49.72 Unrealized @ Report Date -20.8%
COGT COGENT BIOSCIENCES INC 5.2%
Value $14.59M Shares 1,700,000 Share Price $8.58 Est. Cost/Share $10.34 Unrealized @ Report Date -15.9%
CLDX CELLDEX THERAPEUTICS INC NEW 4.8%
Value $13.52M Shares 350,000 Share Price $38.64 * Est. Cost/Share $28.96 Unrealized @ Report Date +50.5%
— RAPT THERAPEUTICS INC 4.6%
Value $12.86M Shares 350,000 Share Price $36.73 Est. Cost/Share $33.20 Unrealized @ Report Date —
— MERUS N V 4.0%
Value $11.13M Shares 350,000 Share Price $31.80 Est. Cost/Share $29.50 Unrealized @ Report Date —
— IVERIC BIO INC 3.7%
Value $10.45M Shares 625,000 Share Price $16.72 Est. Cost/Share $7.44 Unrealized @ Report Date —
VRDN VIRIDIAN THERAPEUTICS INC 3.5%
Value $9.885M Shares 500,000 Share Price $19.77 * Est. Cost/Share $18.53 Unrealized @ Report Date +0.5%
IOVA IOVANCE BIOTHERAPEUTICS INC 3.4%
Value $9.545M Shares 500,000 Share Price $19.09 * Est. Cost/Share $24.32 Unrealized @ Report Date -9.5%
RCKT ROCKET PHARMACEUTICALS INC 3.3%
Value $9.278M Shares 425,000 Share Price $21.83 * Est. Cost/Share $29.94 Unrealized @ Report Date -8.9%
ARVN ARVINAS INC 3.2%
Value $9.035M Shares 110,000 Share Price $82.14 Est. Cost/Share $28.07 Unrealized @ Report Date +189.9%
SRPT SAREPTA THERAPEUTICS INC 3.2%
Value $9.005M Shares 100,000 Share Price $90.05 * Est. Cost/Share $85.49 Unrealized @ Report Date 0.0%
— BELLUS HEALTH INC NEW 2.6%
Value $7.173M Shares 891,000 Share Price $8.05 Est. Cost/Share $6.35 Unrealized @ Report Date —
ZNTL ZENTALIS PHARMACEUTICALS INC 2.4%
Value $6.725M Shares 80,000 Share Price $84.06 * Est. Cost/Share $61.38 Unrealized @ Report Date +26.1%
SNDX SYNDAX PHARMACEUTICALS INC 2.4%
Value $6.567M Shares 300,000 Share Price $21.89 * Est. Cost/Share $18.21 Unrealized @ Report Date +1.5%
PCVX VAXCYTE INC 2.1%
Value $5.948M Shares 250,000 Share Price $23.79 * Est. Cost/Share $21.70 Unrealized @ Report Date +7.2%
FOLD AMICUS THERAPEUTICS INC 2.1%
Value $5.775M Shares 500,000 Share Price $11.55 * Est. Cost/Share $12.96 Unrealized @ Report Date -14.0%
— SIERRA ONCOLOGY INC 1.9%
Value $5.435M Shares 250,000 Share Price $21.74 Est. Cost/Share $17.17 Unrealized @ Report Date —
ALNY ALNYLAM PHARMACEUTICALS INC 1.8%
Value $5.087M Shares 30,000 Share Price $169.57 * Est. Cost/Share $185.86 Unrealized @ Report Date 0.0%
— VERONA PHARMA PLC 1.8%
Value $5.04M Shares 750,000 Share Price $6.72 Est. Cost/Share $6.53 Unrealized @ Report Date —
WHWK AADI BIOSCIENCE INC 1.7%
Value $4.83M Shares 200,000 Share Price $24.15 * Est. Cost/Share $25.11 Unrealized @ Report Date 0.0%
ACRS ACLARIS THERAPEUTICS INC 1.7%
Value $4.726M Shares 325,000 Share Price $14.54 * Est. Cost/Share $6.81 Unrealized @ Report Date +122.5%
CMPS COMPASS PATHWAYS PLC 1.7%
Value $4.641M Shares 210,000 Share Price $22.10 Est. Cost/Share $25.80 Unrealized @ Report Date —
RLMD RELMADA THERAPEUTICS INC 1.6%
Value $4.506M Shares 200,000 Share Price $22.53 Est. Cost/Share $26.77 Unrealized @ Report Date -16.9%
— MIRATI THERAPEUTICS INC 1.6%
Value $4.401M Shares 30,000 Share Price $146.70 Est. Cost/Share $98.34 Unrealized @ Report Date —
— LEAP THERAPEUTICS INC 1.6%
Value $4.374M Shares 1,350,000 Share Price $3.24 Est. Cost/Share $4.01 Unrealized @ Report Date —
— KEZAR LIFE SCIENCES INC 1.5%
Value $4.18M Shares 250,000 Share Price $16.72 Est. Cost/Share $16.72 Unrealized @ Report Date —
— SATSUMA PHARMACEUTICALS INC 1.5%
Value $4.069M Shares 904,225 Share Price $4.50 Est. Cost/Share $10.24 Unrealized @ Report Date —
— VISTAGEN THERAPEUTICS INC 1.4%
Value $3.9M Shares 2,000,000 Share Price $1.95 Est. Cost/Share $2.02 Unrealized @ Report Date —
TARS TARSUS PHARMACEUTICALS INC 1.4%
Value $3.825M Shares 170,000 Share Price $22.50 * Est. Cost/Share $31.23 Unrealized @ Report Date -16.8%
— BELLUS HEALTH INC NEW 1.3%
Value $3.623M Shares 450,000 Share Price $8.05 Est. Cost/Share $6.35 Unrealized @ Report Date —
CRNX CRINETICS PHARMACEUTICALS IN 1.2%
Value $3.362M Shares 118,344 Share Price $28.41 * Est. Cost/Share $17.57 Unrealized @ Report Date +40.3%
PYXS PYXIS ONCOLOGY INC 1.2%
Value $3.236M Shares 295,000 Share Price $10.97 * Est. Cost/Share $11.45 Unrealized @ Report Date 0.0%
— 9 METERS BIOPHARMA INC 1.1%
Value $3.181M Shares 3,250,000 Share Price $0.98 Est. Cost/Share $1.25 Unrealized @ Report Date —
KURA KURA ONCOLOGY INC 1.1%
Value $3.15M Shares 225,000 Share Price $14.00 * Est. Cost/Share $28.09 Unrealized @ Report Date -42.3%
XENE XENON PHARMACEUTICALS INC 1.1%
Value $3.124M Shares 100,000 Share Price $31.24 * Est. Cost/Share $13.60 Unrealized @ Report Date +119.7%
— CTI BIOPHARMA CORP 1.1%
Value $2.976M Shares 1,200,000 Share Price $2.48 Est. Cost/Share $2.84 Unrealized @ Report Date —
DSGN DESIGN THERAPEUTICS INC 1.0%
Value $2.89M Shares 135,000 Share Price $21.41 * Est. Cost/Share $17.17 Unrealized @ Report Date 0.0%
LRMR LARIMAR THERAPEUTICS INC 0.9%
Value $2.428M Shares 225,000 Share Price $10.79 * Est. Cost/Share $11.59 Unrealized @ Report Date -4.1%
GHRS GH RESEARCH PLC 0.8%
Value $2.333M Shares 100,000 Share Price $23.33 * Est. Cost/Share $20.35 Unrealized @ Report Date +7.9%
— GLOBAL BLOOD THERAPEUTICS IN 0.6%
Value $1.756M Shares 60,000 Share Price $29.27 Est. Cost/Share $29.27 Unrealized @ Report Date —
IMUX IMMUNIC INC 0.6%
Value $1.579M Shares 165,000 Share Price $9.57 * Est. Cost/Share $16.38 Unrealized @ Report Date -45.0%
— REATA PHARMACEUTICALS INC 0.5%
Value $1.45M Shares 55,000 Share Price $26.36 Est. Cost/Share $26.36 Unrealized @ Report Date —
ALDX ALDEYRA THERAPEUTICS INC 0.4%
Value $1.2M Shares 300,000 Share Price $4.00 * Est. Cost/Share $4.92 Unrealized @ Report Date +54.9%
— PARDES BIOSCIENCES INC 0.3%
Value $819K Shares 50,000 Share Price $16.38 Est. Cost/Share $16.38 Unrealized @ Report Date —
CABA CABALETTA BIO INC 0.2%
Value $512K Shares 135,000 Share Price $3.79 * Est. Cost/Share $9.60 Unrealized @ Report Date +11.2%