Ghost Tree Capital, LLC Hedge Fund

CIK: 0001595851 · Show all filings

Period: Q1 2023 (← Previous) (Next →)

Filing Date: May 15, 2023

Total Value: $338M (100.0% shares, 0.0% debt)

Holdings (58)

— REATA PHARMACEUTICALS INC 8.1%
Value $27.28M Shares 300,000 Share Price $90.92 Est. Cost/Share $25.13 Unrealized @ Report Date —
XBI SPDR SER TR 6.8%
Value $22.86M Shares 300,000 Share Price $76.21 Est. Cost/Share — Unrealized @ Report Date —
SRPT SAREPTA THERAPEUTICS INC 5.1%
Value $17.23M Shares 125,000 Share Price $137.83 * Est. Cost/Share $82.45 Unrealized @ Report Date +57.3%
TGTX TG THERAPEUTICS INC 4.9%
Value $16.54M Shares 1,100,000 Share Price $15.04 Est. Cost/Share $15.19 Unrealized @ Report Date 0.0%
AMLX AMYLYX PHARMACEUTICALS INC 4.1%
Value $13.94M Shares 475,000 Share Price $29.34 * Est. Cost/Share $27.53 Unrealized @ Report Date +26.2%
AXSM AXSOME THERAPEUTICS INC 4.1%
Value $13.88M Shares 225,000 Share Price $61.68 * Est. Cost/Share $36.01 Unrealized @ Report Date +82.4%
ASND ASCENDIS PHARMA A/S 3.5%
Value $11.79M Shares 110,000 Share Price $107.22 Est. Cost/Share $124.74 Unrealized @ Report Date —
APLS APELLIS PHARMACEUTICALS INC 3.2%
Value $10.86M Shares 164,620 Share Price $65.96 * Est. Cost/Share $51.57 Unrealized @ Report Date +11.9%
— AKERO THERAPEUTICS INC 3.1%
Value $10.52M Shares 275,000 Share Price $38.26 Est. Cost/Share $43.37 Unrealized @ Report Date —
VKTX VIKING THERAPEUTICS INC 3.0%
Value $9.99M Shares 600,000 Share Price $16.65 * Est. Cost/Share $7.40 Unrealized @ Report Date +39.6%
PCVX VAXCYTE INC 2.5%
Value $8.433M Shares 225,000 Share Price $37.48 * Est. Cost/Share $28.02 Unrealized @ Report Date +51.4%
— CTI BIOPHARMA CORP 2.5%
Value $8.4M Shares 2,000,000 Share Price $4.20 Est. Cost/Share $4.65 Unrealized @ Report Date —
SRPT SAREPTA THERAPEUTICS INC 2.4%
Value $8.27M Shares 60,000 Share Price $137.83 * Est. Cost/Share $82.45 Unrealized @ Report Date +57.3%
PFE PFIZER INC 2.4%
Value $8.16M Shares 200,000 Share Price $40.80 * Est. Cost/Share $36.55 Unrealized @ Report Date 0.0%
— REVANCE THERAPEUTICS INC 2.4%
Value $8.053M Shares 250,000 Share Price $32.21 Est. Cost/Share $27.00 Unrealized @ Report Date —
JNJ JOHNSON & JOHNSON 2.3%
Value $7.75M Shares 50,000 Share Price $155.00 * Est. Cost/Share $147.89 Unrealized @ Report Date 0.0%
QURE UNIQURE NV 2.2%
Value $7.553M Shares 375,000 Share Price $20.14 * Est. Cost/Share $20.98 Unrealized @ Report Date 0.0%
MDGL MADRIGAL PHARMACEUTICALS INC 2.1%
Value $7.268M Shares 30,000 Share Price $242.27 * Est. Cost/Share $137.14 Unrealized @ Report Date +98.7%
XENE XENON PHARMACEUTICALS INC 2.1%
Value $7.158M Shares 200,000 Share Price $35.79 * Est. Cost/Share $36.94 Unrealized @ Report Date 0.0%
SNDX SYNDAX PHARMACEUTICALS INC 2.0%
Value $6.864M Shares 325,000 Share Price $21.12 * Est. Cost/Share $21.80 Unrealized @ Report Date +14.1%
— REATA PHARMACEUTICALS INC 1.9%
Value $6.364M Shares 70,000 Share Price $90.91 Est. Cost/Share $25.13 Unrealized @ Report Date —
IOVA IOVANCE BIOTHERAPEUTICS INC 1.8%
Value $6.11M Shares 1,000,000 Share Price $6.11 * Est. Cost/Share $7.81 Unrealized @ Report Date -11.6%
— ASTRIA THERAPEUTICS INC 1.8%
Value $5.985M Shares 450,000 Share Price $13.30 Est. Cost/Share $9.04 Unrealized @ Report Date —
COGT COGENT BIOSCIENCES INC 1.8%
Value $5.935M Shares 550,000 Share Price $10.79 * Est. Cost/Share $10.85 Unrealized @ Report Date +17.8%
INCY INCYTE CORP 1.6%
Value $5.42M Shares 75,000 Share Price $72.27 * Est. Cost/Share $78.23 Unrealized @ Report Date 0.0%
FOLD AMICUS THERAPEUTICS INC 1.6%
Value $5.268M Shares 475,000 Share Price $11.09 * Est. Cost/Share $12.33 Unrealized @ Report Date 0.0%
— MIRATI THERAPEUTICS INC 1.5%
Value $5.205M Shares 140,000 Share Price $37.18 Est. Cost/Share $68.40 Unrealized @ Report Date —
PTGX PROTAGONIST THERAPEUTICS INC 1.5%
Value $5.175M Shares 225,000 Share Price $23.00 * Est. Cost/Share $16.79 Unrealized @ Report Date 0.0%
VRDN VIRIDIAN THERAPEUTICS INC 1.3%
Value $4.452M Shares 175,000 Share Price $25.44 * Est. Cost/Share $18.24 Unrealized @ Report Date +75.8%
— IVERIC BIO INC 1.3%
Value $4.258M Shares 175,000 Share Price $24.33 Est. Cost/Share $7.65 Unrealized @ Report Date —
MLTX MOONLAKE IMMUNOTHERAPEUTICS 1.2%
Value $4.171M Shares 195,000 Share Price $21.39 * Est. Cost/Share $16.81 Unrealized @ Report Date 0.0%
— AEROVATE THERAPEUTICS INC 1.2%
Value $4.034M Shares 200,000 Share Price $20.17 Est. Cost/Share $17.75 Unrealized @ Report Date —
BMEA BIOMEA FUSION INC 1.1%
Value $3.721M Shares 120,000 Share Price $31.01 * Est. Cost/Share $12.43 Unrealized @ Report Date 0.0%
ACRS ACLARIS THERAPEUTICS INC 1.0%
Value $3.438M Shares 425,000 Share Price $8.09 * Est. Cost/Share $12.69 Unrealized @ Report Date 0.0%
APLS APELLIS PHARMACEUTICALS INC 1.0%
Value $3.423M Shares 51,900 Share Price $65.95 * Est. Cost/Share $51.57 Unrealized @ Report Date +11.9%
— KARUNA THERAPEUTICS INC 0.9%
Value $3.179M Shares 17,500 Share Price $181.66 Est. Cost/Share $144.21 Unrealized @ Report Date —
— 89BIO INC 0.9%
Value $3.046M Shares 200,000 Share Price $15.23 Est. Cost/Share $15.23 Unrealized @ Report Date —
BCRX BIOCRYST PHARMACEUTICALS INC 0.7%
Value $2.294M Shares 275,000 Share Price $8.34 * Est. Cost/Share $13.89 Unrealized @ Report Date -30.7%
— AMBRX BIOPHARMA INC 0.7%
Value $2.23M Shares 250,000 Share Price $8.92 Est. Cost/Share $8.92 Unrealized @ Report Date —
— RAIN ONCOLOGY INC 0.6%
Value $2.185M Shares 250,000 Share Price $8.74 Est. Cost/Share $8.74 Unrealized @ Report Date —
IRON DISC MEDICINE INC 0.6%
Value $2.119M Shares 100,000 Share Price $21.19 * Est. Cost/Share $22.28 Unrealized @ Report Date 0.0%
RNAM AVIDITY BIOSCIENCES INC 0.6%
Value $1.919M Shares 125,000 Share Price $15.35 * Est. Cost/Share $16.33 Unrealized @ Report Date +34.7%
ALT ALTIMMUNE INC 0.5%
Value $1.688M Shares 400,000 Share Price $4.22 Est. Cost/Share — Unrealized @ Report Date —
— PROMETHEUS BIOSCIENCES INC 0.5%
Value $1.61M Shares 15,000 Share Price $107.33 Est. Cost/Share $109.12 Unrealized @ Report Date —
— ALPINE IMMUNE SCIENCES INC 0.5%
Value $1.544M Shares 200,000 Share Price $7.72 Est. Cost/Share $7.72 Unrealized @ Report Date —
— 89BIO INC 0.5%
Value $1.523M Shares 100,000 Share Price $15.23 Est. Cost/Share $15.23 Unrealized @ Report Date —
RCUS ARCUS BIOSCIENCES INC 0.4%
Value $1.368M Shares 75,000 Share Price $18.24 * Est. Cost/Share $19.11 Unrealized @ Report Date 0.0%
— FUSION PHARMACEUTICALS INC 0.4%
Value $1.32M Shares 350,000 Share Price $3.77 Est. Cost/Share $3.77 Unrealized @ Report Date —
WHWK AADI BIOSCIENCE INC 0.3%
Value $1.086M Shares 150,000 Share Price $7.24 * Est. Cost/Share $17.55 Unrealized @ Report Date -39.1%
TARS TARSUS PHARMACEUTICALS INC 0.3%
Value $1.006M Shares 80,000 Share Price $12.57 * Est. Cost/Share $31.23 Unrealized @ Report Date -53.2%
GERN GERON CORP 0.3%
Value $977K Shares 450,000 Share Price $2.17 * Est. Cost/Share $2.84 Unrealized @ Report Date 0.0%
— X4 PHARMACEUTICALS INC 0.2%
Value $740K Shares 850,000 Share Price $0.87 Est. Cost/Share $0.99 Unrealized @ Report Date —
— SPRINGWORKS THERAPEUTICS INC 0.2%
Value $710K Shares 27,578 Share Price $25.75 Est. Cost/Share $25.75 Unrealized @ Report Date —
— KEZAR LIFE SCIENCES INC 0.2%
Value $548K Shares 175,000 Share Price $3.13 Est. Cost/Share $14.73 Unrealized @ Report Date —
— FIBROGEN INC 0.1%
Value $494K Shares 26,500 Share Price $18.64 Est. Cost/Share $18.64 Unrealized @ Report Date —
— IMMUNOGEN INC 0.1%
Value $480K Shares 124,977 Share Price $3.84 Est. Cost/Share $3.84 Unrealized @ Report Date —
BBIO BRIDGEBIO PHARMA INC 0.1%
Value $415K Shares 25,000 Share Price $16.60 * Est. Cost/Share $11.66 Unrealized @ Report Date 0.0%
VNDA VANDA PHARMACEUTICALS INC 0.0%
Value $85,000 Shares 12,500 Share Price $6.80 * Est. Cost/Share $7.03 Unrealized @ Report Date 0.0%