Location: Boston, MA
CIK: 0001816307 · Show all filings
Period: Q3 2025 (← Previous) (Next →)
Filing Date: Nov 12, 2025
Total Value: $742M (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| ABVX | ABIVAX SA | 539,704 | $45.82M | 6.2% | $84.90 | — | SPONSORED ADS | 00370M103 |
| RYTM | RHYTHM PHARMACEUTICALS INC | 369,996 | $37.37M | 5.0% | $39.46 | +135.3% | COM | 76243J105 |
| RNAM | AVIDITY BIOSCIENCES INC | 844,633 | $36.8M | 5.0% | $30.30 | +33.4% | COM | 05370A108 |
| NUVL | NUVALENT INC | 372,300 | $32.2M | 4.3% | $73.68 | +7.3% | COM | 670703107 |
| URGN | UROGEN PHARMA LTD | 1,577,283 | $31.47M | 4.2% | $12.41 | +44.7% | COM | M96088105 |
| — | AKERO THERAPEUTICS INC | 643,636 | $30.56M | 4.1% | $24.40 | — | COM | 00973Y108 |
| INSM | INSMED INC | 206,648 | $29.76M | 4.0% | $56.86 | +115.5% | COM PAR $.01 | 457669307 |
| DNTH | DIANTHUS THERAPEUTICS INC | 674,966 | $26.56M | 3.6% | $25.06 | +2.0% | COM | 252828108 |
| QURE | UNIQURE NV | 455,000 | $26.56M | 3.6% | $15.14 | +20.0% | SHS | N90064101 |
| CGON | CG ONCOLOGY INC | 638,346 | $25.71M | 3.5% | $24.86 | +17.0% | COM | 156944100 |
| — | UNITED THERAPEUTICS CORP DEL | 59,900 | $25.11M | 3.4% | — | — | Put | 91307C952 |
| ORIC | ORIC PHARMACEUTICALS INC | 1,948,808 | $23.39M | 3.2% | $6.76 | +55.7% | COM | 68622P109 |
| — | CIDARA THERAPEUTICS INC | 220,902 | $21.15M | 2.9% | $73.62 | — | COM NEW | 171757206 |
| GUTS | FRACTYL HEALTH INC | 10,600,000 | $16.85M | 2.3% | $1.40 | -7.0% | COM | 35168W103 |
| KALV | KALVISTA PHARMACEUTICALS INC | 1,363,378 | $16.61M | 2.2% | $10.97 | +25.9% | COM | 483497103 |
| KOD | KODIAK SCIENCES INC | 1,000,000 | $16.37M | 2.2% | $7.07 | +21.8% | COM | 50015M109 |
| — | ULTRAGENYX PHARMACEUTICAL IN | 528,200 | $15.89M | 2.1% | — | — | Call | 90400D908 |
| GOSS | GOSSAMER BIO INC | 4,779,082 | $12.57M | 1.7% | $1.12 | +96.2% | COM | 38341P102 |
| COGT | COGENT BIOSCIENCES INC | 815,075 | $11.7M | 1.6% | $11.85 | 0.0% | COM | 19240Q201 |
| CYTK | CYTOKINETICS INC | 211,000 | $11.6M | 1.6% | $41.20 | 0.0% | COM NEW | 23282W605 |
| PCVX | VAXCYTE INC | 314,339 | $11.32M | 1.5% | $32.81 | +1.0% | COM | 92243G108 |
| BIIB | BIOGEN INC | 80,419 | $11.27M | 1.5% | $135.17 | 0.0% | COM | 09062X103 |
| ASND | ASCENDIS PHARMA A/S | 53,554 | $10.65M | 1.4% | $147.80 | — | SPONSORED ADR | 04351P101 |
| CMPX | COMPASS THERAPEUTICS INC | 2,833,988 | $9.919M | 1.3% | $2.86 | +10.5% | COM | 20454B104 |
| AMLX | AMYLYX PHARMACEUTICALS INC | 700,000 | $9.513M | 1.3% | $9.41 | 0.0% | COM | 03237H101 |
| VSTM | VERASTEM INC | 1,042,757 | $9.208M | 1.2% | $7.44 | 0.0% | COM NEW | 92337C203 |
| AVTX | AVALO THERAPEUTICS INC | 720,922 | $9.163M | 1.2% | $8.60 | 0.0% | COM NEW | 05338F306 |
| OLMA | OLEMA PHARMACEUTICALS INC | 933,541 | $9.139M | 1.2% | $6.00 | 0.0% | COM | 68062P106 |
| CLDX | CELLDEX THERAPEUTICS INC NEW | 348,922 | $9.027M | 1.2% | $27.17 | -14.7% | COM NEW | 15117B202 |
| SRRK | SCHOLAR ROCK HLDG CORP | 233,920 | $8.711M | 1.2% | $31.39 | +11.4% | COM | 80706P103 |
| VCYT | VERACYTE INC | 235,791 | $8.095M | 1.1% | $31.10 | -7.7% | COM | 92337F107 |
| SNDX | SYNDAX PHARMACEUTICALS INC | 463,708 | $7.134M | 1.0% | $17.39 | -24.7% | COM | 87164F105 |
| RAPP | RAPPORT THERAPEUTICS INC | 203,946 | $6.057M | 0.8% | $17.84 | 0.0% | COM | 75383L102 |
| VRDN | VIRIDIAN THERAPEUTICS INC | 259,509 | $5.6M | 0.8% | $18.04 | 0.0% | COM | 92790C104 |
| ALKS | ALKERMES PLC | 180,513 | $5.415M | 0.7% | $28.20 | 0.0% | SHS | G01767105 |
| TRVI | TREVI THERAPEUTICS INC | 588,789 | $5.387M | 0.7% | $3.55 | +111.1% | COM | 89532M101 |
| BBOT | BRIDGEBIO ONCOLOGY THERAPEUT | 457,414 | $5.297M | 0.7% | $11.58 | — | COM NEW | 107924102 |
| ABEO | ABEONA THERAPEUTICS INC | 994,754 | $5.252M | 0.7% | $5.74 | +10.4% | COM NEW | 00289Y206 |
| LXEO | LEXEO THERAPEUTICS INC | 778,611 | $5.17M | 0.7% | $4.84 | 0.0% | COM | 52886X107 |
| — | COGENT BIOSCIENCES INC | 360,000 | $5.17M | 0.7% | — | — | Call | 19240Q901 |
| GLUE | MONTE ROSA THERAPEUTICS INC | 694,942 | $5.15M | 0.7% | $5.30 | 0.0% | COM | 61225M102 |
| CGEN | COMPUGEN LTD | 3,311,165 | $4.867M | 0.7% | $1.60 | -7.3% | ORD | M25722105 |
| PHVS | PHARVARIS N V | 183,903 | $4.588M | 0.6% | $22.18 | 0.0% | COM | N69605108 |
| CELC | CELCUITY INC | 88,686 | $4.381M | 0.6% | $40.03 | 0.0% | COM | 15102K100 |
| CERS | CERUS CORP | 2,715,786 | $4.318M | 0.6% | $3.32 | -59.3% | COM | 157085101 |
| CCCC | C4 THERAPEUTICS INC | 1,897,383 | $4.212M | 0.6% | $2.40 | 0.0% | COM STK | 12529R107 |
| TELA | TELA BIO INC | 2,782,923 | $4.147M | 0.6% | $4.46 | -60.5% | COM | 872381108 |
| AARD | AARDVARK THERAPEUTICS INC | 306,912 | $4.079M | 0.6% | $10.73 | +5.1% | COM | 002942100 |
| BCAX | BICARA THERAPEUTICS INC | 250,606 | $3.957M | 0.5% | $11.19 | 0.0% | COM | 055477103 |
| BNTC | BENITEC BIOPHARMA INC | 276,267 | $3.876M | 0.5% | $12.18 | +4.8% | COM NEW | 08205P209 |
| KNSA | KINIKSA PHARMACEUTICALS INTL | 88,910 | $3.452M | 0.5% | $22.32 | +45.6% | ORD SHS CL A | G52694109 |
| CNTA | CENTESSA PHARMACEUTICALS PLC | 141,238 | $3.425M | 0.5% | $23.96 | — | SPONSORED ADS | 152309100 |
| EYPT | EYEPOINT PHARMACEUTICALS INC | 230,837 | $3.287M | 0.4% | $11.51 | 0.0% | COM NEW | 30233G209 |
| SION | SIONNA THERAPEUTICS INC | 108,801 | $3.2M | 0.4% | $15.09 | +44.2% | COM | 829401108 |
| ZURA | ZURA BIO LTD | 720,452 | $3.12M | 0.4% | $1.80 | 0.0% | CLASS A ORD SHS | G9TY5A101 |
| MLYS | MINERALYS THERAPEUTICS INC | 80,000 | $3.034M | 0.4% | $11.50 | +88.1% | COM | 603170101 |
| ERAS | ERASCA INC | 1,368,075 | $2.982M | 0.4% | $2.20 | -27.7% | COM | 29479A108 |
| PRAX | PRAXIS PRECISION MEDICINES I | 51,210 | $2.714M | 0.4% | $47.77 | +1.5% | COM NEW | 74006W207 |
| ELUT | ELUTIA INC | 2,850,987 | $2.538M | 0.3% | $3.14 | -40.9% | CL A COM | 05479K106 |
| DCTH | DELCATH SYS INC | 203,386 | $2.186M | 0.3% | $11.20 | -0.3% | COM NEW | 24661P807 |
| CRNX | CRINETICS PHARMACEUTICALS IN | 50,000 | $2.083M | 0.3% | $31.97 | 0.0% | COM | 22663K107 |
| CAMP | CAMP4 THERAPEUTICS CORP | 653,594 | $1.961M | 0.3% | $1.85 | 0.0% | COM | 13463J101 |
| CTNM | CONTINEUM THERAPEUTICS INC | 166,161 | $1.952M | 0.3% | $8.06 | 0.0% | CL A | 21217B100 |
| DYN | DYNE THERAPEUTICS INC | 100,000 | $1.265M | 0.2% | $11.41 | 0.0% | COM | 26818M108 |
| LBRX | LB PHARMACEUTICALS INC | 70,000 | $1.105M | 0.1% | $15.87 | 0.0% | COM SHS | 50180M108 |
| — | CAPRICOR THERAPEUTICS INC | 144,700 | $1.043M | 0.1% | — | — | Put | 14070B959 |
| — | MERSANA THERAPEUTICS INC | 133,636 | $1.037M | 0.1% | $7.76 | — | COM | 59045L205 |
| RADX | RADIOPHARM THERANOSTICS LTD | 187,406 | $1.034M | 0.1% | $4.49 | — | SPONSORED ADS | 75041J101 |
| — | ATYR PHARMA INC | 1,250,000 | $901K | 0.1% | — | — | Put | 002120952 |
| IMVT | IMMUNOVANT INC | 50,000 | $806K | 0.1% | $16.19 | 0.0% | COM | 45258J102 |
| — | ARCTURUS THERAPEUTICS HLDGS | 42,000 | $774K | 0.1% | — | — | Put | 03969T959 |
| — | SYNDAX PHARMACEUTICALS INC | 50,000 | $770K | 0.1% | — | — | Call | 87164F905 |
| — | ULTRAGENYX PHARMACEUTICAL IN | 25,000 | $752K | 0.1% | — | — | Put | 90400D958 |
| — | MOONLAKE IMMUNOTHERAPEUTICS | 65,000 | $466K | 0.1% | — | — | Call | 61559X904 |
| MODD | MODULAR MED INC | 639,531 | $448K | 0.1% | $1.79 | -60.0% | COM NEW | 60785L207 |
| BDSX | BIODESIX INC | 49,607 | $375K | 0.1% | $7.69 | 0.0% | COM | 09075X207 |
| MBX | MBX BIOSCIENCES INC | 15,000 | $263K | 0.0% | $13.37 | 0.0% | COM | 55287L101 |
| ELVN | ENLIVEN THERAPEUTICS INC | 10,675 | $219K | 0.0% | $19.01 | +6.0% | COM | 29337E102 |
| MLTX | MOONLAKE IMMUNOTHERAPEUTICS | 30,000 | $215K | 0.0% | $40.73 | +27.9% | CLASS A ORD | 61559X104 |
| ARCT | ARCTURUS THERAPEUTICS HLDGS | 3,445 | $63,491 | 0.0% | $16.06 | 0.0% | COM | 03969T109 |
| NKTR | NEKTAR THERAPEUTICS | 365 | $20,769 | 0.0% | $12.37 | +167.5% | COM NEW | 640268306 |
| RCKTW | ROCKET PHARMACEUTICALS INC | 104,828 | $4,109 | 0.0% | $0.11 | — | *W EXP 09/02/202 | 77313F114 |