ACUTA CAPITAL PARTNERS, LLC Hedge Fund

CIK: 0001582844 · Show all filings

Period: Q4 2019 (← Previous) (Next →)

Filing Date: Feb 14, 2020

Total Value ($000): $403,795 (100.0% shares, 0.0% debt)

Holdings (38)

AXSM AXSOME THERAPEUTICS INC 15.6%

Value ($000) $62,791 Shares 607,500 Est. Cost $23.68 Unrealized +70.6%

XBI SPDR SERIES TRUST 11.8%

Value ($000) $47,555 Shares 500,000 Est. Cost — Unrealized —

ARWR ARROWHEAD PHARMACEUTICALS IN 7.0%

Value ($000) $28,068 Shares 442,500 Est. Cost $23.72 Unrealized +109.2%

— KADMON HLDGS INC 6.8%

Value ($000) $27,361 Shares 6,040,000 Est. Cost $3.68 Unrealized —

AUPH AURINIA PHARMACEUTICALS INC 5.3%

Value ($000) $21,425 Shares 1,057,500 Est. Cost $6.93 Unrealized +32.9%

— INTRA CELLULAR THERAPIES INC 5.0%

Value ($000) $20,143 Shares 587,089 Est. Cost $34.31 Unrealized —

IOVA IOVANCE BIOTHERAPEUTICS INC 4.5%

Value ($000) $18,172 Shares 656,500 Est. Cost $7.92 Unrealized +187.3%

— ADVERUM BIOTECHNOLOGIES INC 3.8%

Value ($000) $15,235 Shares 1,322,500 Est. Cost $11.52 Unrealized —

ARVN ARVINAS INC 3.6%

Value ($000) $14,628 Shares 356,000 Est. Cost $19.30 Unrealized +51.7%

— AVADEL PHARMACEUTICALS PLC 3.0%

Value ($000) $12,269 Shares 1,625,000 Est. Cost $7.55 Unrealized —

XENE XENON PHARMACEUTICALS INC 3.0%

Value ($000) $12,028 Shares 917,500 Est. Cost $8.16 Unrealized +29.0%

— KARYOPHARM THERAPEUTICS INC 2.8%

Value ($000) $11,310 Shares 590,000 Est. Cost $15.33 Unrealized —

BCRX BIOCRYST PHARMACEUTICALS 2.4%

Value ($000) $9,746 Shares 2,825,000 Est. Cost $2.52 Unrealized 0.0%

— CONSTELLATION PHARMCETICLS I 2.3%

Value ($000) $9,304 Shares 197,500 Est. Cost $47.11 Unrealized —

— DICERNA PHARMACEUTICALS INC 2.1%

Value ($000) $8,537 Shares 387,500 Est. Cost $22.03 Unrealized —

MIST MILESTONE PHARMACEUTICALS IN 2.0%

Value ($000) $8,141 Shares 508,500 Est. Cost $19.80 Unrealized -10.3%

— IVERIC BIO INC 1.9%

Value ($000) $7,808 Shares 910,000 Est. Cost $8.58 Unrealized —

— REATA PHARMACEUTICALS INC 1.9%

Value ($000) $7,768 Shares 38,000 Est. Cost $80.29 Unrealized —

— BELLUS HEALTH INC NEW 1.5%

Value ($000) $6,156 Shares 810,000 Est. Cost $6.43 Unrealized —

APLS APELLIS PHARMACEUTICALS INC 1.4%

Value ($000) $5,741 Shares 187,500 Est. Cost $27.68 Unrealized 0.0%

— SELECTA BIOSCIENCES INC 1.3%

Value ($000) $5,345 Shares 2,364,204 Est. Cost $2.26 Unrealized —

— NEOLEUKIN THERAPEUTICS INC 1.1%

Value ($000) $4,589 Shares 372,500 Est. Cost $12.32 Unrealized —

— KARUNA THERAPEUTICS INC 1.0%

Value ($000) $4,219 Shares 56,000 Est. Cost $75.34 Unrealized —

— APPLIED THERAPEUTICS INC 1.0%

Value ($000) $4,037 Shares 148,000 Est. Cost $18.14 Unrealized —

INSM INSMED INC 1.0%

Value ($000) $4,036 Shares 169,000 Est. Cost $26.21 Unrealized -22.4%

— INTRA CELLULAR THERAPIES INC 0.8%

Value ($000) $3,431 Shares 100,000 Est. Cost $34.31 Unrealized —

KURA KURA ONCOLOGY INC 0.8%

Value ($000) $3,300 Shares 240,000 Est. Cost $16.00 Unrealized -7.4%

— ZYMEWORKS INC 0.8%

Value ($000) $3,205 Shares 70,500 Est. Cost $30.08 Unrealized —

— IMMUNOMEDICS INC 0.8%

Value ($000) $3,174 Shares 150,000 Est. Cost $21.16 Unrealized —

ASND ASCENDIS PHARMA A S 0.8%

Value ($000) $3,130 Shares 22,500 Est. Cost $139.11 Unrealized —

KALV KALVISTA PHARMACEUTICALS INC 0.5%

Value ($000) $1,915 Shares 107,500 Est. Cost $13.85 Unrealized -5.8%

— MEDICINES CO 0.5%

Value ($000) $1,843 Shares 21,700 Est. Cost $84.93 Unrealized —

QURE UNIQURE NV 0.4%

Value ($000) $1,792 Shares 25,000 Est. Cost $54.91 Unrealized 0.0%

— ACASTI PHARMA INC 0.4%

Value ($000) $1,519 Shares 620,000 Est. Cost $2.45 Unrealized —

— CHEMOCENTRYX INC 0.3%

Value ($000) $1,384 Shares 35,000 Est. Cost $39.54 Unrealized —

— ADVERUM BIOTECHNOLOGIES INC 0.3%

Value ($000) $1,152 Shares 100,000 Est. Cost $11.52 Unrealized —

— ZAFGEN INC 0.3%

Value ($000) $1,110 Shares 1,000,000 Est. Cost $1.11 Unrealized —

— X4 PHARMACEUTICALS INC 0.1%

Value ($000) $428 Shares 40,000 Est. Cost $10.70 Unrealized —

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
AXSM	AXSOME THERAPEUTICS INC	607,500	$62,791	15.6%	$23.68	+70.6%	COM	05464T104
XBI	SPDR SERIES TRUST	500,000	$47,555	11.8%	—	—	Put	78464A870
ARWR	ARROWHEAD PHARMACEUTICALS IN	442,500	$28,068	7.0%	$23.72	+109.2%	COM	04280A100
—	KADMON HLDGS INC	6,040,000	$27,361	6.8%	$3.68	—	COM	48283N106
AUPH	AURINIA PHARMACEUTICALS INC	1,057,500	$21,425	5.3%	$6.93	+32.9%	COM	05156V102
—	INTRA CELLULAR THERAPIES INC	587,089	$20,143	5.0%	$34.31	—	COM	46116X101
IOVA	IOVANCE BIOTHERAPEUTICS INC	656,500	$18,172	4.5%	$7.92	+187.3%	COM	462260100
—	ADVERUM BIOTECHNOLOGIES INC	1,322,500	$15,235	3.8%	$11.52	—	COM	00773U108
ARVN	ARVINAS INC	356,000	$14,628	3.6%	$19.30	+51.7%	COM	04335A105
—	AVADEL PHARMACEUTICALS PLC	1,625,000	$12,269	3.0%	$7.55	—	SPONSORED ADR	05337M104
XENE	XENON PHARMACEUTICALS INC	917,500	$12,028	3.0%	$8.16	+29.0%	COM	98420N105
—	KARYOPHARM THERAPEUTICS INC	590,000	$11,310	2.8%	$15.33	—	COM	48576U106
BCRX	BIOCRYST PHARMACEUTICALS	2,825,000	$9,746	2.4%	$2.52	0.0%	COM	09058V103
—	CONSTELLATION PHARMCETICLS I	197,500	$9,304	2.3%	$47.11	—	COM	210373106
—	DICERNA PHARMACEUTICALS INC	387,500	$8,537	2.1%	$22.03	—	COM	253031108
MIST	MILESTONE PHARMACEUTICALS IN	508,500	$8,141	2.0%	$19.80	-10.3%	COM	59935V107
—	IVERIC BIO INC	910,000	$7,808	1.9%	$8.58	—	COM	46583P102
—	REATA PHARMACEUTICALS INC	38,000	$7,768	1.9%	$80.29	—	CL A	75615P103
—	BELLUS HEALTH INC NEW	810,000	$6,156	1.5%	$6.43	—	COM NEW	07987C204
APLS	APELLIS PHARMACEUTICALS INC	187,500	$5,741	1.4%	$27.68	0.0%	COM	03753U106
—	SELECTA BIOSCIENCES INC	2,364,204	$5,345	1.3%	$2.26	—	COM	816212104
—	NEOLEUKIN THERAPEUTICS INC	372,500	$4,589	1.1%	$12.32	—	COM	64049K104
—	KARUNA THERAPEUTICS INC	56,000	$4,219	1.0%	$75.34	—	COM	48576A100
—	APPLIED THERAPEUTICS INC	148,000	$4,037	1.0%	$18.14	—	COM	03828A101
INSM	INSMED INC	169,000	$4,036	1.0%	$26.21	-22.4%	COM PAR $.01	457669307
—	INTRA CELLULAR THERAPIES INC	100,000	$3,431	0.8%	$34.31	—	Call	46116X101
KURA	KURA ONCOLOGY INC	240,000	$3,300	0.8%	$16.00	-7.4%	COM	50127T109
—	ZYMEWORKS INC	70,500	$3,205	0.8%	$30.08	—	COM	98985W102
—	IMMUNOMEDICS INC	150,000	$3,174	0.8%	$21.16	—	COM	452907108
ASND	ASCENDIS PHARMA A S	22,500	$3,130	0.8%	$139.11	—	SPONSORED ADR	04351P101
KALV	KALVISTA PHARMACEUTICALS INC	107,500	$1,915	0.5%	$13.85	-5.8%	COM	483497103
—	MEDICINES CO	21,700	$1,843	0.5%	$84.93	—	COM	584688105
QURE	UNIQURE NV	25,000	$1,792	0.4%	$54.91	0.0%	SHS	N90064101
—	ACASTI PHARMA INC	620,000	$1,519	0.4%	$2.45	—	CL A NEW	00430K402
—	CHEMOCENTRYX INC	35,000	$1,384	0.3%	$39.54	—	COM	16383L106
—	ADVERUM BIOTECHNOLOGIES INC	100,000	$1,152	0.3%	$11.52	—	Call	00773U108
—	ZAFGEN INC	1,000,000	$1,110	0.3%	$1.11	—	COM	98885E103
—	X4 PHARMACEUTICALS INC	40,000	$428	0.1%	$10.70	—	COM	98420X103