ACUTA CAPITAL PARTNERS, LLC Hedge Fund

Location: Redwood City, CA

CIK: 0001582844 · Show all filings

Period: Q3 2020 (← Previous) (Next →)

Filing Date: Nov 16, 2020

Total Value: $368M (100.0% shares, 0.0% debt)

Holdings (43)

— IMMUNOMEDICS INC 11.8%

Value $43.49M Shares 511,500 Est. Cost $35.44 Unrealized —

KURA KURA ONCOLOGY INC 8.1%

Value $29.81M Shares 973,000 Est. Cost $15.54 Unrealized +42.1%

XBI SPDR SER TR 7.6%

Value $27.86M Shares 250,000 Est. Cost — Unrealized —

CLDX CELLDEX THERAPEUTICS INC NEW 6.2%

Value $22.91M Shares 1,545,000 Est. Cost $7.00 Unrealized +67.3%

— SAGE THERAPEUTICS INC 3.7%

Value $13.75M Shares 225,000 Est. Cost $61.12 Unrealized —

CMPS COMPASS PATHWAYS PLC 3.7%

Value $13.61M Shares 390,000 Est. Cost $34.90 Unrealized —

LRMR LARIMAR THERAPEUTICS INC 3.4%

Value $12.59M Shares 830,000 Est. Cost $11.65 Unrealized +8.7%

— MERSANA THERAPEUTICS INC 3.4%

Value $12.43M Shares 667,500 Est. Cost $6.50 Unrealized —

ALDX ALDEYRA THERAPEUTICS INC 3.3%

Value $12.2M Shares 1,646,700 Est. Cost $4.94 Unrealized +30.7%

— TRILLIUM THERAPEUTICS INC 3.3%

Value $12.12M Shares 853,000 Est. Cost $14.21 Unrealized —

— 89BIO INC 2.9%

Value $10.71M Shares 417,500 Est. Cost $25.66 Unrealized —

RLMD RELMADA THERAPEUTICS INC 2.8%

Value $10.42M Shares 277,000 Est. Cost $41.08 Unrealized -5.9%

IOVA IOVANCE BIOTHERAPEUTICS INC 2.8%

Value $10.37M Shares 315,000 Est. Cost $15.98 Unrealized +91.9%

ALT ALTIMMUNE INC 2.5%

Value $9.082M Shares 688,000 Est. Cost $8.67 Unrealized +130.7%

IMVT IMMUNOVANT INC 2.4%

Value $8.798M Shares 250,000 Est. Cost $21.43 Unrealized +40.4%

CYTK CYTOKINETICS INC 2.1%

Value $7.74M Shares 357,500 Est. Cost $23.39 Unrealized 0.0%

— RAPT THERAPEUTICS INC 2.1%

Value $7.728M Shares 240,000 Est. Cost $32.20 Unrealized —

— LIFESCI ACQUISITION CORP 2.1%

Value $7.616M Shares 560,000 Est. Cost $10.00 Unrealized —

— SURFACE ONCOLOGY INC 2.0%

Value $7.507M Shares 1,088,000 Est. Cost $6.83 Unrealized —

— ATHIRA PHARMA INC 1.8%

Value $6.692M Shares 362,500 Est. Cost $18.46 Unrealized —

RNAM AVIDITY BIOSCIENCES INC 1.8%

Value $6.615M Shares 235,000 Est. Cost $28.87 Unrealized +0.1%

— CATALYST BIOSCIENCES INC 1.7%

Value $6.441M Shares 1,497,900 Est. Cost $4.48 Unrealized —

— SELECTA BIOSCIENCES INC 1.6%

Value $5.863M Shares 2,364,204 Est. Cost $2.26 Unrealized —

— CYMABAY THERAPEUTICS INC 1.5%

Value $5.539M Shares 765,000 Est. Cost $7.24 Unrealized —

APLS APELLIS PHARMACEUTICALS INC 1.4%

Value $5.04M Shares 167,054 Est. Cost $28.50 Unrealized +4.8%

— IVERIC BIO INC 1.2%

Value $4.526M Shares 802,500 Est. Cost $5.78 Unrealized —

ARWR ARROWHEAD PHARMACEUTICALS IN 1.2%

Value $4.371M Shares 101,500 Est. Cost $31.66 Unrealized +36.3%

CRDF CARDIFF ONCOLOGY INC 1.2%

Value $4.341M Shares 305,900 Est. Cost $2.05 Unrealized +222.8%

— HEALTH SCIENCES ACQ CORP 2 1.2%

Value $4.318M Shares 392,500 Est. Cost $11.00 Unrealized —

— AVADEL PHARMACEUTICALS PLC 1.0%

Value $3.554M Shares 705,218 Est. Cost $7.66 Unrealized —

SNDX SYNDAX PHARMACEUTICALS INC 1.0%

Value $3.553M Shares 240,744 Est. Cost $15.23 Unrealized +0.1%

— PANACEA ACQUISITION CORP 0.9%

Value $3.36M Shares 280,000 Est. Cost $12.00 Unrealized —

ANNX ANNEXON INC 0.9%

Value $3.325M Shares 110,000 Est. Cost $23.46 Unrealized 0.0%

XENE XENON PHARMACEUTICALS INC 0.9%

Value $3.321M Shares 300,000 Est. Cost $8.16 Unrealized +44.3%

FULC FULCRUM THERAPEUTICS INC 0.8%

Value $3.025M Shares 381,500 Est. Cost $12.04 Unrealized 0.0%

— CONCERT PHARMACEUTICALS INC 0.8%

Value $2.946M Shares 300,000 Est. Cost $9.82 Unrealized —

— VERASTEM INC 0.8%

Value $2.904M Shares 2,400,000 Est. Cost $2.55 Unrealized —

BCRX BIOCRYST PHARMACEUTICALS 0.6%

Value $2.267M Shares 660,000 Est. Cost $3.80 Unrealized +12.8%

AXSM AXSOME THERAPEUTICS INC 0.4%

Value $1.603M Shares 22,500 Est. Cost $23.68 Unrealized +229.1%

— KARUNA THERAPEUTICS INC 0.3%

Value $1.044M Shares 13,500 Est. Cost $85.53 Unrealized —

— UNUM THERAPEUTICS INC 0.3%

Value $959K Shares 410,000 Est. Cost $2.34 Unrealized —

— CLEARSIDE BIOMEDICAL INC 0.3%

Value $947K Shares 615,000 Est. Cost $1.54 Unrealized —

WVE WAVE LIFE SCIENCES LTD 0.2%

Value $913K Shares 107,500 Est. Cost $9.41 Unrealized +16.5%

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
—	IMMUNOMEDICS INC	511,500	$43.49M	11.8%	$35.44	—	COM	452907108
KURA	KURA ONCOLOGY INC	973,000	$29.81M	8.1%	$15.54	+42.1%	COM	50127T109
XBI	SPDR SER TR	250,000	$27.86M	7.6%	—	—	Put	78464A870
CLDX	CELLDEX THERAPEUTICS INC NEW	1,545,000	$22.91M	6.2%	$7.00	+67.3%	COM NEW	15117B202
—	SAGE THERAPEUTICS INC	225,000	$13.75M	3.7%	$61.12	—	COM	78667J108
CMPS	COMPASS PATHWAYS PLC	390,000	$13.61M	3.7%	$34.90	—	SPONSORED ADS	20451W101
LRMR	LARIMAR THERAPEUTICS INC	830,000	$12.59M	3.4%	$11.65	+8.7%	COM	517125100
—	MERSANA THERAPEUTICS INC	667,500	$12.43M	3.4%	$6.50	—	COM	59045L106
ALDX	ALDEYRA THERAPEUTICS INC	1,646,700	$12.2M	3.3%	$4.94	+30.7%	COM	01438T106
—	TRILLIUM THERAPEUTICS INC	853,000	$12.12M	3.3%	$14.21	—	COM NEW	89620X506
—	89BIO INC	417,500	$10.71M	2.9%	$25.66	—	COM	282559103
RLMD	RELMADA THERAPEUTICS INC	277,000	$10.42M	2.8%	$41.08	-5.9%	COM	75955J402
IOVA	IOVANCE BIOTHERAPEUTICS INC	315,000	$10.37M	2.8%	$15.98	+91.9%	COM	462260100
ALT	ALTIMMUNE INC	688,000	$9.082M	2.5%	$8.67	+130.7%	COM NEW	02155H200
IMVT	IMMUNOVANT INC	250,000	$8.798M	2.4%	$21.43	+40.4%	COM	45258J102
CYTK	CYTOKINETICS INC	357,500	$7.74M	2.1%	$23.39	0.0%	COM NEW	23282W605
—	RAPT THERAPEUTICS INC	240,000	$7.728M	2.1%	$32.20	—	COM	75382E109
—	LIFESCI ACQUISITION CORP	560,000	$7.616M	2.1%	$10.00	—	UNIT 03/31/2025	53228P208
—	SURFACE ONCOLOGY INC	1,088,000	$7.507M	2.0%	$6.83	—	COM	86877M209
—	ATHIRA PHARMA INC	362,500	$6.692M	1.8%	$18.46	—	COM	04746L104
RNAM	AVIDITY BIOSCIENCES INC	235,000	$6.615M	1.8%	$28.87	+0.1%	COM	05370A108
—	CATALYST BIOSCIENCES INC	1,497,900	$6.441M	1.7%	$4.48	—	COM NEW	14888D208
—	SELECTA BIOSCIENCES INC	2,364,204	$5.863M	1.6%	$2.26	—	COM	816212104
—	CYMABAY THERAPEUTICS INC	765,000	$5.539M	1.5%	$7.24	—	COM	23257D103
APLS	APELLIS PHARMACEUTICALS INC	167,054	$5.04M	1.4%	$28.50	+4.8%	COM	03753U106
—	IVERIC BIO INC	802,500	$4.526M	1.2%	$5.78	—	COM	46583P102
ARWR	ARROWHEAD PHARMACEUTICALS IN	101,500	$4.371M	1.2%	$31.66	+36.3%	COM	04280A100
CRDF	CARDIFF ONCOLOGY INC	305,900	$4.341M	1.2%	$2.05	+222.8%	COM	14147L108
—	HEALTH SCIENCES ACQ CORP 2	392,500	$4.318M	1.2%	$11.00	—	ORD SHS	G4411D109
—	AVADEL PHARMACEUTICALS PLC	705,218	$3.554M	1.0%	$7.66	—	SPONSORED ADR	05337M104
SNDX	SYNDAX PHARMACEUTICALS INC	240,744	$3.553M	1.0%	$15.23	+0.1%	COM	87164F105
—	PANACEA ACQUISITION CORP	280,000	$3.36M	0.9%	$12.00	—	UNIT 99/99/9999	698102209
ANNX	ANNEXON INC	110,000	$3.325M	0.9%	$23.46	0.0%	COM	03589W102
XENE	XENON PHARMACEUTICALS INC	300,000	$3.321M	0.9%	$8.16	+44.3%	COM	98420N105
FULC	FULCRUM THERAPEUTICS INC	381,500	$3.025M	0.8%	$12.04	0.0%	COM	359616109
—	CONCERT PHARMACEUTICALS INC	300,000	$2.946M	0.8%	$9.82	—	COM	206022105
—	VERASTEM INC	2,400,000	$2.904M	0.8%	$2.55	—	COM	92337C104
BCRX	BIOCRYST PHARMACEUTICALS	660,000	$2.267M	0.6%	$3.80	+12.8%	COM	09058V103
AXSM	AXSOME THERAPEUTICS INC	22,500	$1.603M	0.4%	$23.68	+229.1%	COM	05464T104
—	KARUNA THERAPEUTICS INC	13,500	$1.044M	0.3%	$85.53	—	COM	48576A100
—	UNUM THERAPEUTICS INC	410,000	$959K	0.3%	$2.34	—	COM	903214104
—	CLEARSIDE BIOMEDICAL INC	615,000	$947K	0.3%	$1.54	—	COM	185063104
WVE	WAVE LIFE SCIENCES LTD	107,500	$913K	0.2%	$9.41	+16.5%	SHS	Y95308105