Location: New York, NY
CIK: 0001590144 · Show all filings
Period: Q1 2021 (← Previous) (Next →)
Filing Date: May 12, 2021
Total Value: $3.509B (99.8% shares, 0.2% debt)
| Ticker | Issuer | Shares | Value | % | Share Price | Est. Cost/Share | Unrealized @ Report Date | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|---|
| QQQ | INVESCO QQQ TR | 1,075,000 | $343M | 9.8% | $319.13 | — | — | Put | 46090E103 |
| SPY | SPDR S&P 500 ETF TR | 850,000 | $337M | 9.6% | $396.33 | — | — | Put | 78462F103 |
| IWM | ISHARES TR | 1,392,500 | $308M | 8.8% | $220.94 | — | — | Put | 464287655 |
| XBI | SPDR SER TR | 1,650,000 | $224M | 6.4% | $135.65 | — | — | Put | 78464A870 |
| XLV | SELECT SECTOR SPDR TR | 1,000,000 | $117M | 3.3% | $116.74 | — | — | Put | 81369Y209 |
| ARKK | ARK ETF TR | 622,500 | $74.67M | 2.1% | $119.95 | — | — | Put | 00214Q104 |
| ESTA | ESTABLISHMENT LABS HLDGS INC | 1,100,834 | $68.83M | 2.0% | $62.53 * | $21.85 | +164.0% | COM | G31249108 |
| — | NANOSTRING TECHNOLOGIES INC | 1,009,027 | $66.3M | 1.9% | $65.71 | $23.13 | — | COM | 63009R109 |
| — | ONCOCYTE CORP | 12,223,953 | $63.44M | 1.8% | $5.19 | $3.67 | — | COM | 68235C107 |
| ARKG | ARK ETF TR | 700,000 | $62.11M | 1.8% | $88.73 | — | — | Put | 00214Q302 |
| IBB | ISHARES TR | 350,000 | $52.7M | 1.5% | $150.56 | — | — | Put | 464287556 |
| — | INOVALON HLDGS INC | 1,648,358 | $47.44M | 1.4% | $28.78 | $19.82 | — | COM CL A | 45781D101 |
| MCK | MCKESSON CORP | 225,000 | $43.88M | 1.3% | $195.04 | — | — | Put | 58155Q103 |
| FXH | FIRST TR EXCHANGE TRADED FD | 402,000 | $43.66M | 1.2% | $108.61 | — | — | Put | 33734X143 |
| INSP | INSPIRE MED SYS INC | 204,187 | $42.27M | 1.2% | $206.99 * | $52.28 | +306.5% | COM | 457730109 |
| VRAYQ | VIEWRAY INC | 9,632,701 | $41.9M | 1.2% | $4.35 * | $3.87 | +25.4% | COM | 92672L107 |
| ATRC | ATRICURE INC | 615,950 | $40.36M | 1.2% | $65.52 * | $39.63 | +55.4% | COM | 04963C209 |
| CI | CIGNA CORP NEW | 160,000 | $38.68M | 1.1% | $241.74 | — | — | Put | 125523100 |
| PPH | VANECK VECTORS ETF TR | 550,000 | $37.96M | 1.1% | $69.02 | — | — | Put | 92189F692 |
| — | MEDAVAIL HOLDINGS INC | 2,342,213 | $31.63M | 0.9% | $13.51 | $14.25 | — | COM | 58406B103 |
| ICUI | ICU MED INC | 148,548 | $30.52M | 0.9% | $205.44 * | $206.68 | +2.2% | COM | 44930G107 |
| STAA | STAAR SURGICAL CO | 287,238 | $30.28M | 0.9% | $105.41 * | $37.56 | +166.6% | COM PAR $0.01 | 852312305 |
| UNH | UNITEDHEALTH GROUP INC | 75,000 | $27.91M | 0.8% | $372.07 | — | — | Put | 91324P102 |
| ORGO | ORGANOGENESIS HLDGS INC | 1,507,552 | $27.47M | 0.8% | $18.22 * | $4.75 | +185.3% | COM | 68621F102 |
| — | HYDROFARM HLDGS GROUP INC | 448,324 | $27.04M | 0.8% | $60.32 | $53.85 | — | COM | 44888K209 |
| NTRA | NATERA INC | 247,644 | $25.15M | 0.7% | $101.54 * | $67.81 | +61.6% | COM | 632307104 |
| DXCM | DEXCOM INC | 67,500 | $24.26M | 0.7% | $359.39 * | $35.56 | +164.0% | Put | 252131107 |
| ILMN | ILLUMINA INC | 62,500 | $24M | 0.7% | $384.06 | — | — | Put | 452327109 |
| — | ALEXION PHARMACEUTICALS INC | 156,581 | $23.94M | 0.7% | $152.91 | $107.02 | — | COM | 015351109 |
| — | R1 RCM INC | 946,487 | $23.36M | 0.7% | $24.68 | $11.48 | — | COM | 749397105 |
| — | APRIA INC | 766,712 | $21.41M | 0.6% | $27.93 | $27.93 | — | COM | 03836A101 |
| VCEL | VERICEL CORP | 374,435 | $20.8M | 0.6% | $55.55 * | $16.55 | +173.4% | COM | 92346J108 |
| LUNG | PULMONX CORP | 442,896 | $20.26M | 0.6% | $45.74 * | $49.92 | +14.9% | COM | 745848101 |
| — | OUTSET MED INC | 364,267 | $19.81M | 0.6% | $54.39 | $52.22 | — | COM | 690145107 |
| PACB | PACIFIC BIOSCIENCES CALIF IN | 586,955 | $19.55M | 0.6% | $33.31 * | $5.76 | +508.0% | COM | 69404D108 |
| — | INTERSECT ENT INC | 909,660 | $18.99M | 0.5% | $20.88 | $18.47 | — | COM | 46071F103 |
| ALGN | ALIGN TECHNOLOGY INC | 35,000 | $18.95M | 0.5% | $541.54 * | $552.79 | 0.0% | COM | 016255101 |
| LIVN | LIVANOVA PLC | 252,402 | $18.61M | 0.5% | $73.73 * | $55.61 | +28.3% | SHS | G5509L101 |
| ABT | ABBOTT LABS | 150,000 | $17.98M | 0.5% | $119.84 | — | — | Put | 002824100 |
| MDT | MEDTRONIC PLC | 150,000 | $17.72M | 0.5% | $118.13 | — | — | Put | G5960L103 |
| SIBN | SI BONE INC | 550,104 | $17.5M | 0.5% | $31.81 * | $19.65 | +56.5% | COM | 825704109 |
| — | COOPER COS INC | 45,500 | $17.48M | 0.5% | $384.09 | $384.09 | — | Call | 216648402 |
| — | AMYRIS INC | 845,022 | $16.14M | 0.5% | $19.10 | $13.75 | — | COM NEW | 03236M200 |
| NTLA | INTELLIA THERAPEUTICS INC | 198,300 | $15.91M | 0.5% | $80.26 * | $67.12 | 0.0% | Call | 45826J105 |
| GH | GUARDANT HEALTH INC | 103,908 | $15.86M | 0.5% | $152.65 | $96.26 | +57.0% | COM | 40131M109 |
| ZBH | ZIMMER BIOMET HOLDINGS INC | 98,948 | $15.84M | 0.5% | $160.08 * | $117.95 | +26.1% | COM | 98956P102 |
| PROF | PROFOUND MED CORP | 771,593 | $15.54M | 0.4% | $20.14 * | $13.73 | +74.7% | COM NEW | 74319B502 |
| NTLA | INTELLIA THERAPEUTICS INC | 190,000 | $15.25M | 0.4% | $80.25 * | $67.12 | 0.0% | COM | 45826J105 |
| — | EARGO INC | 304,800 | $15.22M | 0.4% | $49.95 | — | — | Put | 270087109 |
| — | CUTERA INC | 500,805 | $15.05M | 0.4% | $30.05 | $30.05 | — | COM | 232109108 |
| — | INVACARE CORP | 1,828,095 | $14.66M | 0.4% | $8.02 | $8.13 | — | COM | 461203101 |
| QTRX | QUANTERIX CORP | 241,328 | $14.11M | 0.4% | $58.47 * | $46.89 | +44.2% | COM | 74766Q101 |
| — | JAWS ACQUISITION CORP | 1,047,466 | $13.88M | 0.4% | $13.25 | $13.36 | — | SHS | G50744104 |
| SDGR | SCHRODINGER INC | 180,596 | $13.78M | 0.4% | $76.29 * | $72.45 | +24.1% | COM | 80810D103 |
| PSNL | PERSONALIS INC | 548,052 | $13.49M | 0.4% | $24.61 * | $23.01 | +49.0% | COM | 71535D106 |
| — | OLINK HLDG AB | 373,300 | $13.44M | 0.4% | $36.00 | $36.00 | — | SPONSORED ADS | 680710100 |
| BVS | BIOVENTUS INC | 877,062 | $13.4M | 0.4% | $15.28 * | $14.24 | 0.0% | COM CL A | 09075A108 |
| — | CM LIFE SCIENCES II INC | 1,037,863 | $13.29M | 0.4% | $12.80 | $12.80 | — | UNIT 02/25/2028 | 125842203 |
| SEER | SEER INC | 261,923 | $13.1M | 0.4% | $50.02 * | $63.62 | -8.0% | COM CL A | 81578P106 |
| TXG | 10X GENOMICS INC | 70,704 | $12.8M | 0.4% | $180.99 * | $114.45 | +50.9% | CL A COM | 88025U109 |
| DMTKQ | DERMTECH INC | 245,306 | $12.46M | 0.4% | $50.79 | $11.93 | — | COM | 24984K105 |
| MDXG | MIMEDX GROUP INC | 1,136,951 | $11.71M | 0.3% | $10.30 * | $7.16 | +34.9% | COM | 602496101 |
| NVST | ENVISTA HOLDINGS CORPORATION | 283,176 | $11.55M | 0.3% | $40.80 * | $32.15 | +18.5% | COM | 29415F104 |
| IART | INTEGRA LIFESCIENCES HLDGS C | 165,400 | $11.43M | 0.3% | $69.09 | — | — | Put | 457985208 |
| TPB | TURNING PT BRANDS INC | 217,543 | $11.35M | 0.3% | $52.17 * | $39.48 | +26.3% | COM | 90041L105 |
| CDXS | CODEXIS INC | 480,935 | $11.01M | 0.3% | $22.89 * | $17.84 | +31.1% | COM | 192005106 |
| STXS | STEREOTAXIS INC | 1,626,533 | $10.93M | 0.3% | $6.72 * | $4.91 | +20.8% | COM NEW | 85916J409 |
| CSTL | CASTLE BIOSCIENCES INC | 156,000 | $10.68M | 0.3% | $68.46 | — | — | Put | 14843C105 |
| FLGT | FULGENT GENETICS INC | 110,000 | $10.63M | 0.3% | $96.62 | — | — | Put | 359664109 |
| ADPT | ADAPTIVE BIOTECHNOLOGIES COR | 256,694 | $10.34M | 0.3% | $40.26 * | $41.37 | +30.8% | COM | 00650F109 |
| — | SIGNIFY HEALTH INC | 345,757 | $10.12M | 0.3% | $29.26 | $29.26 | — | CL A COM | 82671G100 |
| — | MISONIX INC | 504,757 | $9.888M | 0.3% | $19.59 | $10.64 | — | COM | 604871103 |
| ICUI | ICU MED INC | 47,800 | $9.82M | 0.3% | $205.44 * | $206.68 | +2.2% | Call | 44930G107 |
| DXCM | DEXCOM INC | 26,742 | $9.611M | 0.3% | $359.40 * | $35.56 | +164.0% | COM | 252131107 |
| APYX | APYX MEDICAL CORPORATION | 958,488 | $9.259M | 0.3% | $9.66 * | $5.99 | +66.9% | COM | 03837C106 |
| TMO | THERMO FISHER SCIENTIFIC INC | 20,000 | $9.128M | 0.3% | $456.40 | — | — | Put | 883556102 |
| — | INARI MED INC | 85,000 | $9.095M | 0.3% | $107.00 | $61.93 | — | COM | 45332Y109 |
| CGEM | CULLINAN ONCOLOGY INC | 216,630 | $9.027M | 0.3% | $41.67 * | $40.60 | 0.0% | COM | 230031106 |
| INCY | INCYTE CORP | 110,750 | $9.001M | 0.3% | $81.27 * | $85.35 | 0.0% | COM | 45337C102 |
| — | INOVALON HLDGS INC | 303,500 | $8.735M | 0.2% | $28.78 | $19.82 | — | Call | 45781D101 |
| CRL | CHARLES RIV LABS INTL INC | 30,000 | $8.695M | 0.2% | $289.83 | — | — | Put | 159864107 |
| CNMD | CONMED CORP | 65,000 | $8.488M | 0.2% | $130.58 * | $71.43 | +61.5% | COM | 207410101 |
| MRVI | MARAVAI LIFESCIENCES HLDGS I | 236,350 | $8.424M | 0.2% | $35.64 * | $27.85 | +19.0% | COM CL A | 56600D107 |
| RVTY | PERKINELMER INC | 65,000 | $8.339M | 0.2% | $128.29 | — | — | Put | 714046109 |
| — | COOPER COS INC | 21,646 | $8.314M | 0.2% | $384.09 | $384.09 | — | COM NEW | 216648402 |
| TFX | TELEFLEX INCORPORATED | 20,000 | $8.309M | 0.2% | $415.45 | — | — | Put | 879369106 |
| — | ICAD INC | 388,193 | $8.237M | 0.2% | $21.22 | $21.22 | — | COM NEW | 44934S206 |
| — | BIONANO GENOMICS INC | 1,000,000 | $8.08M | 0.2% | $8.08 | $3.08 | — | COM | 09075F107 |
| — | HUDSON EXECUTIVE INVT CORP | 808,089 | $8.016M | 0.2% | $9.92 | $9.92 | — | COM CL A | 443761101 |
| — | QUOTIENT LTD | 2,176,400 | $8.009M | 0.2% | $3.68 | $5.97 | — | SHS | G73268107 |
| — | ORTHO CLINICAL DIAGNOSTICS H | 413,891 | $7.986M | 0.2% | $19.29 | $19.29 | — | ORD SHS | G6829J107 |
| ZBH | ZIMMER BIOMET HOLDINGS INC | 49,800 | $7.972M | 0.2% | $160.08 * | $117.95 | +26.1% | Call | 98956P102 |
| GKOS | GLAUKOS CORP | 92,500 | $7.764M | 0.2% | $83.94 * | $65.20 | +34.9% | COM | 377322102 |
| MRK | MERCK & CO. INC | 100,000 | $7.709M | 0.2% | $77.09 | — | — | Call | 58933Y105 |
| CYRX | CRYOPORT INC | 147,800 | $7.687M | 0.2% | $52.01 | — | — | Put | 229050307 |
| ABCL | ABCELLERA BIOLOGICS INC | 225,000 | $7.641M | 0.2% | $33.96 * | $45.73 | -12.9% | COM | 00288U106 |
| RCEL | AVITA MEDICAL INC | 383,589 | $7.603M | 0.2% | $19.82 * | $23.25 | 0.0% | COM | 05380C102 |
| HOLX | HOLOGIC INC | 100,000 | $7.438M | 0.2% | $74.38 | — | — | Put | 436440101 |
| — | KRATON CORPORATION | 202,500 | $7.409M | 0.2% | $36.59 | — | — | Call | 50077C106 |
| MASS | 908 DEVICES INC | 148,767 | $7.215M | 0.2% | $48.50 * | $58.33 | -2.0% | COM | 65443P102 |
| — | DARIOHEALTH CORP | 374,707 | $6.86M | 0.2% | $18.31 | $18.31 | — | COM NEW | 23725P209 |
| — | CURIS INC | 597,200 | $6.76M | 0.2% | $11.32 | $5.66 | — | Call | 231269200 |
| MRNA | MODERNA INC | 50,600 | $6.626M | 0.2% | $130.95 * | $144.91 | 0.0% | Put | 60770K107 |
| — | IMMUNOGEN INC | 804,192 | $6.514M | 0.2% | $8.10 | $6.84 | — | COM | 45253H101 |
| — | HUMANIGEN INC | 340,200 | $6.498M | 0.2% | $19.10 | — | — | Put | 444863203 |
| INNV | INNOVAGE HLDG CORP | 251,225 | $6.479M | 0.2% | $25.79 * | $24.64 | 0.0% | COM | 45784A104 |
| TELA | TELA BIO INC | 421,202 | $6.276M | 0.2% | $14.90 | $14.42 | +4.4% | COM | 872381108 |
| TNDM | TANDEM DIABETES CARE INC | 70,800 | $6.248M | 0.2% | $88.25 | — | — | Put | 875372203 |
| TMDX | TRANSMEDICS GROUP INC | 150,000 | $6.224M | 0.2% | $41.49 | — | — | Put | 89377M109 |
| FOLD | AMICUS THERAPEUTICS INC | 622,500 | $6.15M | 0.2% | $9.88 * | $13.03 | +18.8% | Call | 03152W109 |
| — | CYTOKINETICS INC | 25,000 | $5.967M | 0.2% | $238.68 | $3.52 | — | NOTE 4.000%11/1 | 23282WAA8 |
| XGN | EXAGEN INC | 331,141 | $5.795M | 0.2% | $17.50 | $17.82 | 0.0% | COM | 30068X103 |
| — | ARYA SCIENCES ACQU CORP IV | 544,164 | $5.699M | 0.2% | $10.47 | $10.47 | — | CL A | G31659108 |
| MGNX | MACROGENICS INC | 175,000 | $5.574M | 0.2% | $31.85 * | $24.28 | 0.0% | Call | 556099109 |
| — | RESEARCH ALLIANCE CORP II | 533,300 | $5.466M | 0.2% | $10.25 | $10.25 | — | COM CL A | 760873109 |
| — | ITAMAR MED LTD | 227,751 | $5.455M | 0.2% | $23.95 | $23.95 | — | SPONSORED ADS | 465437101 |
| — | INTERSECT ENT INC | 256,800 | $5.362M | 0.2% | $20.88 | $18.47 | — | Call | 46071F103 |
| — | MIRATI THERAPEUTICS INC | 30,242 | $5.18M | 0.1% | $171.28 | $187.26 | — | COM | 60468T105 |
| CDNA | CAREDX INC | 70,000 | $4.766M | 0.1% | $68.09 | — | — | Put | 14167L103 |
| — | SILVER SPIKE ACQUISITN CORP | 475,000 | $4.724M | 0.1% | $9.95 | $9.95 | — | UNIT 02/26/2026 | G8201H121 |
| — | HUMANIGEN INC | 245,300 | $4.685M | 0.1% | $19.10 | — | — | Call | 444863203 |
| — | DECIPHERA PHARMACEUTICALS IN | 101,200 | $4.538M | 0.1% | $44.84 | — | — | Call | 24344T101 |
| — | DEERFIELD HEALTHCARE TECH AC | 367,014 | $4.448M | 0.1% | $12.12 | $15.56 | — | COM CL A | 244413100 |
| — | LIFESCI ACQUISITION II CORP | 438,111 | $4.442M | 0.1% | $10.14 | $10.62 | — | COM | 53229E103 |
| ACRS | ACLARIS THERAPEUTICS INC | 175,799 | $4.43M | 0.1% | $25.20 * | $15.19 | +28.7% | COM | 00461U105 |
| ARQT | ARCUTIS BIOTHERAPEUTICS INC | 145,744 | $4.216M | 0.1% | $28.93 * | $31.23 | 0.0% | COM | 03969K108 |
| — | SOLITON INC | 237,650 | $4.176M | 0.1% | $17.57 | $17.57 | — | COM | 834251100 |
| NNOX | NANO X IMAGING LTD | 100,000 | $4.145M | 0.1% | $41.45 | — | — | Put | M70700105 |
| — | ARYA SCIENCES ACQUISITION CO | 295,554 | $4.073M | 0.1% | $13.78 | $13.78 | — | COM CL A | G3166W106 |
| CMPS | COMPASS PATHWAYS PLC | 108,146 | $3.982M | 0.1% | $36.82 | $34.99 | — | SPONSORED ADS | 20451W101 |
| EXAS | EXACT SCIENCES CORP | 30,000 | $3.953M | 0.1% | $131.77 | — | — | Put | 30063P105 |
| — | FORTE BIOSCIENCES INC | 113,466 | $3.888M | 0.1% | $34.27 | $35.50 | — | COM | 34962G109 |
| — | ESSA PHARMA INC | 132,483 | $3.849M | 0.1% | $29.05 | $14.06 | — | COM NEW | 29668H708 |
| KURA | KURA ONCOLOGY INC | 124,240 | $3.512M | 0.1% | $28.27 * | $25.81 | +22.6% | COM | 50127T109 |
| MRNA | MODERNA INC | 26,791 | $3.508M | 0.1% | $130.94 * | $144.91 | 0.0% | COM | 60770K107 |
| BFLYW | BUTTERFLY NETWORK INC | 533,372 | $3.44M | 0.1% | $6.45 | $6.45 | — | *W EXP 05/27/202 | 124155110 |
| CLDX | CELLDEX THERAPEUTICS INC NEW | 163,615 | $3.37M | 0.1% | $20.60 * | $22.96 | 0.0% | COM NEW | 15117B202 |
| — | CONFORMIS INC | 3,396,043 | $3.362M | 0.1% | $0.99 | $0.99 | — | COM | 20717E101 |
| GILD | GILEAD SCIENCES INC | 50,602 | $3.27M | 0.1% | $64.62 * | $53.36 | 0.0% | COM | 375558103 |
| ATRC | ATRICURE INC | 49,800 | $3.263M | 0.1% | $65.52 * | $39.63 | +55.4% | Call | 04963C209 |
| TVTX | TRAVERE THERAPEUTICS INC | 126,533 | $3.16M | 0.1% | $24.97 * | $27.63 | 0.0% | COM | 89422G107 |
| BFLY | BUTTERFLY NETWORK INC | 183,765 | $3.093M | 0.1% | $16.83 * | $19.79 | 0.0% | COM CL A | 124155102 |
| — | FRONTIER ACQUISITION CORP | 300,000 | $2.979M | 0.1% | $9.93 | $9.93 | — | UNIT 03/01/2026 | G36826116 |
| — | MEDTECH ACQUISITION CORP | 290,047 | $2.915M | 0.1% | $10.05 | $10.50 | — | UNIT 12/18/2025 | 58507N204 |
| — | VINCERX PHARMA INC | 149,516 | $2.886M | 0.1% | $19.30 | $20.85 | — | COM NEW | 92731L106 |
| MIST | MILESTONE PHARMACEUTICALS IN | 467,640 | $2.708M | 0.1% | $5.79 * | $6.82 | +7.3% | COM | 59935V107 |
| — | FINCH THERAPEUTICS GROUP INC | 160,000 | $2.584M | 0.1% | $16.15 | $16.15 | — | COM | 31773D101 |
| ACAD | ACADIA PHARMACEUTICALS INC | 100,000 | $2.58M | 0.1% | $25.80 | — | — | Put | 004225108 |
| ZNTL | ZENTALIS PHARMACEUTICALS INC | 56,776 | $2.464M | 0.1% | $43.40 | $43.05 | 0.0% | COM | 98943L107 |
| — | ABG ACQUISITION CORP I | 246,507 | $2.438M | 0.1% | $9.89 | $9.89 | — | CL A SHS | G00496102 |
| VXRT | VAXART INC | 401,500 | $2.429M | 0.1% | $6.05 | — | — | Call | 92243A200 |
| PHAT | PHATHOM PHARMACEUTICALS INC | 63,772 | $2.395M | 0.1% | $37.56 * | $40.59 | +3.1% | COM | 71722W107 |
| — | FREQUENCY THERAPEUTICS INC | 250,000 | $2.375M | 0.1% | $9.50 | $9.50 | — | Put | 35803L108 |
| — | POSEIDA THERAPEUTICS INC | 236,311 | $2.257M | 0.1% | $9.55 | $9.55 | — | COM | 73730P108 |
| VRTX | VERTEX PHARMACEUTICALS INC | 10,243 | $2.201M | 0.1% | $214.88 * | $219.65 | 0.0% | COM | 92532F100 |
| MGNX | MACROGENICS INC | 68,792 | $2.191M | 0.1% | $31.85 * | $24.28 | 0.0% | COM | 556099109 |
| — | 5 01 ACQUISITION CORP | 219,136 | $2.18M | 0.1% | $9.95 | $10.17 | — | COM CL A | 33836P105 |
| — | GREENLANE HLDGS INC | 407,905 | $2.164M | 0.1% | $5.31 | $5.76 | — | CL A | 395330103 |
| ARVN | ARVINAS INC | 32,017 | $2.116M | 0.1% | $66.09 * | $37.13 | +106.0% | COM | 04335A105 |
| — | AVADEL PHARMACEUTICALS PLC | 234,122 | $2.116M | 0.1% | $9.04 | $6.59 | — | SPONSORED ADR | 05337M104 |
| — | PRIVETERRA ACQUISITION CORP | 211,472 | $2.102M | 0.1% | $9.94 | $9.94 | — | UNIT 99/99/9999 | 74275N201 |
| — | CYCLACEL PHARMACEUTICALS INC | 273,958 | $1.948M | 0.1% | $7.11 | $7.81 | — | COM | 23254L603 |
| — | INVITAE CORP | 50,000 | $1.911M | 0.1% | $38.22 | — | — | Put | 46185L103 |
| — | AFFIMED N V | 240,542 | $1.903M | 0.1% | $7.91 | $7.04 | — | COM | N01045108 |
| — | INOVIO PHARMACEUTICALS INC | 200,000 | $1.856M | 0.1% | $9.28 | — | — | Call | 45773H201 |
| — | LOGICBIO THERAPEUTICS INC | 253,102 | $1.843M | 0.1% | $7.28 | $7.63 | — | COM | 54142F102 |
| — | AMERICAN WELL CORP | 100,000 | $1.737M | 0.0% | $17.37 | — | — | Put | 03044L105 |
| — | ACHILLES THERAPEUTICS PLC | 103,026 | $1.705M | 0.0% | $16.55 | $16.55 | — | SPONSORED ADS | 00449L102 |
| CGEN | COMPUGEN LTD | 198,400 | $1.704M | 0.0% | $8.59 | — | — | Call | M25722105 |
| — | VENUS CONCEPT INC | 701,486 | $1.648M | 0.0% | $2.35 | $2.35 | — | COM | 92332W105 |
| — | REPARE THERAPEUTICS INC | 53,640 | $1.646M | 0.0% | $30.69 | $30.69 | — | COM | 760273102 |
| RCUS | ARCUS BIOSCIENCES INC | 56,900 | $1.598M | 0.0% | $28.08 | — | — | Call | 03969F109 |
| CTMX | CYTOMX THERAPEUTICS INC | 202,478 | $1.565M | 0.0% | $7.73 * | $7.92 | 0.0% | COM | 23284F105 |
| — | CHARDAN HEALTHCR ACQSTN 2 CO | 153,960 | $1.547M | 0.0% | $10.05 | $10.05 | — | COM | 15957T107 |
| EXEL | EXELIXIS INC | 66,460 | $1.501M | 0.0% | $22.59 | $22.58 | 0.0% | COM | 30161Q104 |
| — | HUDSON EXECUTIVE INVES III | 150,000 | $1.488M | 0.0% | $9.92 | $9.92 | — | UNIT 02/22/2026 | 44376L206 |
| FULC | FULCRUM THERAPEUTICS INC | 126,068 | $1.485M | 0.0% | $11.78 * | $11.90 | +3.9% | COM | 359616109 |
| — | HUDSON EXECUTIVE INVS CORP I | 150,000 | $1.472M | 0.0% | $9.81 | $9.81 | — | UNIT 01/31/2027 | 443760202 |
| IDYA | IDEAYA BIOSCIENCES INC | 60,744 | $1.427M | 0.0% | $23.49 * | $19.31 | 0.0% | COM | 45166A102 |
| ALT | ALTIMMUNE INC | 100,000 | $1.413M | 0.0% | $14.13 | — | — | Call | 02155H200 |
| — | ONCORUS INC | 101,264 | $1.41M | 0.0% | $13.92 | $13.92 | — | COM | 68236R103 |
| — | ALPINE IMMUNE SCIENCES INC | 131,981 | $1.399M | 0.0% | $10.60 | $12.60 | — | COM | 02083G100 |
| — | HIGHCAPE CAP ACQUISITION COR | 115,477 | $1.376M | 0.0% | $11.92 | $11.92 | — | COM CL A | 42984L105 |
| — | SIERRA ONCOLOGY INC | 77,263 | $1.331M | 0.0% | $17.23 | $15.41 | — | COM NEW | 82640U404 |
| — | YUMANITY THERAPEUTICS INC | 68,853 | $1.246M | 0.0% | $18.10 | $18.10 | — | COM | 98872L102 |
| — | HEALTH SCIENCES ACQ CORP 2 | 109,492 | $1.225M | 0.0% | $11.19 | $11.02 | — | ORD SHS | G4411D109 |
| CMPS | COMPASS PATHWAYS PLC | 30,000 | $1.105M | 0.0% | $36.83 | $34.99 | — | Call | 20451W101 |
| — | APPLIED GENETIC TECHNOLOGIES | 206,423 | $1.047M | 0.0% | $5.07 | $5.07 | — | COM | 03820J100 |
| — | PRECISION BIOSCIENCES INC | 101,104 | $1.046M | 0.0% | $10.35 | $10.35 | — | COM | 74019P108 |
| FOLD | AMICUS THERAPEUTICS INC | 101,300 | $1.001M | 0.0% | $9.88 * | $13.03 | +18.8% | Put | 03152W109 |
| HYPR | HEALTHCOR CATALIO ACQU CORP | 98,227 | $982K | 0.0% | $10.00 | $10.00 | — | CL A SHS | G44125105 |
| — | FREQUENCY THERAPEUTICS INC | 100,000 | $950K | 0.0% | $9.50 | $9.50 | — | Call | 35803L108 |
| — | FREQUENCY THERAPEUTICS INC | 100,000 | $950K | 0.0% | $9.50 | $9.50 | — | COM | 35803L108 |
| — | SENSEI BIOTHERAPEUTICS INC | 67,357 | $941K | 0.0% | $13.97 | $13.97 | — | COM | 81728A108 |
| GOSS | GOSSAMER BIO INC | 100,254 | $927K | 0.0% | $9.25 * | $10.08 | 0.0% | COM | 38341P102 |
| — | LAVA THERAPEUTICS NV | 54,000 | $820K | 0.0% | $15.19 | $15.19 | — | SHS | N51517105 |
| — | VAPOTHERM INC | 29,800 | $716K | 0.0% | $24.03 | — | — | Put | 922107107 |
| — | HUDSON EXECUTIVE INVT CORP | 454,718 | $659K | 0.0% | $1.45 | $1.45 | — | *W EXP 06/21/202 | 443761119 |
| AUPH | AURINIA PHARMACEUTICALS INC | 50,575 | $657K | 0.0% | $12.99 * | $14.51 | 0.0% | COM | 05156V102 |
| — | SOLID BIOSCIENCES INC | 100,000 | $553K | 0.0% | $5.53 | — | — | Call | 83422E105 |
| — | CM LIFE SCIENCES INC | 101,416 | $525K | 0.0% | $5.18 | $5.18 | — | *W EXP 09/04/202 | 18978W117 |
| KALV | KALVISTA PHARMACEUTICALS INC | 20,257 | $520K | 0.0% | $25.67 * | $26.28 | 0.0% | COM | 483497103 |
| BCAB | BIOATLA INC | 8,995 | $457K | 0.0% | $50.81 | $33.43 | +53.3% | COM | 09077B104 |
| FOLD | AMICUS THERAPEUTICS INC | 45,525 | $450K | 0.0% | $9.88 * | $13.03 | +18.8% | COM | 03152W109 |
| — | GOSSAMER BIO INC | 5,000 | $449K | 0.0% | $89.80 | $2.03 | — | NOTE 5.000% 6/0 | 38341PAA0 |
| — | IDERA PHARMACEUTICALS INC | 333,800 | $434K | 0.0% | $1.30 | — | — | Put | 45168K405 |
| MAPSW | SILVER SPIKE ACQUISITION COR | 50,000 | $352K | 0.0% | $7.04 | $0.40 | — | *W EXP 08/02/202 | G8136L114 |
| MREO | MEREO BIOPHARMA GROUP PLC | 100,514 | $339K | 0.0% | $3.37 | $3.37 | — | ADS | 589492107 |
| IRD | OCUPHIRE PHARMA INC | 57,536 | $334K | 0.0% | $5.81 * | $9.29 | 0.0% | COM | 67577R102 |
| — | INOVIO PHARMACEUTICALS INC | 32,300 | $300K | 0.0% | $9.29 | — | — | Put | 45773H201 |
| NKTX | NKARTA INC | 7,919 | $261K | 0.0% | $32.96 * | $41.53 | +15.0% | COM | 65487U108 |
| SVRA | SAVARA INC | 100,000 | $208K | 0.0% | $2.08 * | $1.71 | 0.0% | COM | 805111101 |
| — | IDERA PHARMACEUTICALS INC | 160,000 | $208K | 0.0% | $1.30 | — | — | Call | 45168K405 |
| — | TUATARA CAPITAL ACQUISITN CO | 20,000 | $200K | 0.0% | $10.00 | $10.00 | — | UNIT 99/99/9999 | G9118J127 |
| — | CHARDAN HEALTHCR ACQSTN 2 CO | 153,960 | $145K | 0.0% | $0.94 | $0.94 | — | *W EXP 03/05/202 | 15957T115 |