EcoR1 Capital, LLC Quant / Systematic

Location: San Francisco, CA

CIK: 0001587114 · Show all filings

Period: Q2 2018 (← Previous) (Next →)

Filing Date: Aug 14, 2018

Total Value: $1.05B (100.0% shares, 0.0% debt)

Holdings (33)

— FIBROGEN INC 12.0%

Value $126M Shares 2,017,250 Est. Cost $36.02 Unrealized —

IRWD IRONWOOD PHARMACEUTICALS INC 11.4%

Value $120M Shares 6,250,073 Est. Cost $11.88 Unrealized +24.6%

— ASSEMBLY BIOSCIENCES INC 11.0%

Value $115M Shares 2,943,164 Est. Cost $8.38 Unrealized —

ASND ASCENDIS PHARMA A S 9.3%

Value $97.39M Shares 1,464,067 Est. Cost $26.79 Unrealized —

KURA KURA ONCOLOGY INC 6.8%

Value $71.06M Shares 3,904,675 Est. Cost $10.03 Unrealized +68.8%

MDGL MADRIGAL PHARMACEUTICALS INC 5.3%

Value $55.8M Shares 199,500 Est. Cost $175.60 Unrealized 0.0%

— CELGENE CORP 4.4%

Value $46.46M Shares 585,000 Est. Cost — Unrealized —

SRRK SCHOLAR ROCK HLDG CORP 4.0%

Value $41.67M Shares 2,671,161 Est. Cost $18.88 Unrealized 0.0%

— DICERNA PHARMACEUTICALS INC 3.5%

Value $36.27M Shares 2,961,147 Est. Cost $7.99 Unrealized —

MGNX MACROGENICS INC 2.9%

Value $29.95M Shares 1,450,606 Est. Cost $19.87 Unrealized +13.4%

— ASCENDIS PHARMA A S 2.8%

Value $29.73M Shares 447,000 Est. Cost — Unrealized —

RCUS ARCUS BIOSCIENCES INC 2.6%

Value $27.37M Shares 2,236,387 Est. Cost $16.66 Unrealized -5.8%

— UNITY BIOTECHNOLOGY INC 2.4%

Value $25.31M Shares 1,680,644 Est. Cost $15.06 Unrealized —

— KEZAR LIFE SCIENCES INC 2.1%

Value $22.01M Shares 1,272,198 Est. Cost $17.30 Unrealized —

— FIBROGEN INC 2.1%

Value $21.91M Shares 350,000 Est. Cost — Unrealized —

SGMO SANGAMO THERAPEUTICS INC 2.0%

Value $21.44M Shares 1,509,671 Est. Cost $16.61 Unrealized 0.0%

— MAGENTA THERAPEUTICS INC 2.0%

Value $20.76M Shares 1,538,088 Est. Cost $13.50 Unrealized —

— GILEAD SCIENCES INC 2.0%

Value $20.73M Shares 292,600 Est. Cost — Unrealized —

— IMMUNE DESIGN CORP 1.9%

Value $20.19M Shares 4,437,600 Est. Cost $3.77 Unrealized —

WVE WAVE LIFE SCIENCES LTD 1.5%

Value $15.79M Shares 412,871 Est. Cost $30.27 Unrealized +42.2%

— SURFACE ONCOLOGY INC 1.4%

Value $14.53M Shares 890,808 Est. Cost $16.31 Unrealized —

— EIGER BIOPHARMACEUTICALS INC 1.2%

Value $12.68M Shares 1,039,500 Est. Cost $12.20 Unrealized —

— IRONWOOD PHARMACEUTICALS INC 1.1%

Value $11.04M Shares 577,600 Est. Cost — Unrealized —

— ACHILLION PHARMACEUTICALS INC 1.0%

Value $11M Shares 3,887,407 Est. Cost $3.26 Unrealized —

— KADMON HLDGS INC 0.9%

Value $9.975M Shares 2,500,000 Est. Cost $3.99 Unrealized —

— ASSEMBLY BIOSCIENCES INC 0.6%

Value $5.807M Shares 148,100 Est. Cost — Unrealized —

— DBV TECHNOLOGIES S A 0.5%

Value $5.75M Shares 298,100 Est. Cost $23.07 Unrealized —

CRVS CORVUS PHARMACEUTICALS INC 0.5%

Value $4.945M Shares 450,400 Est. Cost $11.04 Unrealized +1.2%

— AQUINOX PHARMACEUTICALS INC 0.3%

Value $3.048M Shares 1,150,000 Est. Cost $2.65 Unrealized —

— ONCONOVA THERAPEUTICS INC 0.3%

Value $3.034M Shares 7,500,000 Est. Cost $0.40 Unrealized —

— ERYTECH PHARMA 0.2%

Value $1.734M Shares 153,964 Est. Cost $11.26 Unrealized —

— APTINYX INC 0.1%

Value $992K Shares 41,037 Est. Cost $24.17 Unrealized —

INFIQ INFINITY PHARMACEUTICALS INC 0.1%

Value $787K Shares 412,000 Est. Cost $2.02 Unrealized 0.0%

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
—	FIBROGEN INC	2,017,250	$126M	12.0%	$36.02	—	COM	31572Q808
IRWD	IRONWOOD PHARMACEUTICALS INC	6,250,073	$120M	11.4%	$11.88	+24.6%	COM	46333X108
—	ASSEMBLY BIOSCIENCES INC	2,943,164	$115M	11.0%	$8.38	—	COM	045396108
ASND	ASCENDIS PHARMA A S	1,464,067	$97.39M	9.3%	$26.79	—	SPONSORED ADR	04351P101
KURA	KURA ONCOLOGY INC	3,904,675	$71.06M	6.8%	$10.03	+68.8%	COM	50127T109
MDGL	MADRIGAL PHARMACEUTICALS INC	199,500	$55.8M	5.3%	$175.60	0.0%	COM	558868105
—	CELGENE CORP	585,000	$46.46M	4.4%	—	—	Call	151020904
SRRK	SCHOLAR ROCK HLDG CORP	2,671,161	$41.67M	4.0%	$18.88	0.0%	COM	80706P103
—	DICERNA PHARMACEUTICALS INC	2,961,147	$36.27M	3.5%	$7.99	—	COM	253031108
MGNX	MACROGENICS INC	1,450,606	$29.95M	2.9%	$19.87	+13.4%	COM	556099109
—	ASCENDIS PHARMA A S	447,000	$29.73M	2.8%	—	—	Call	04351P901
RCUS	ARCUS BIOSCIENCES INC	2,236,387	$27.37M	2.6%	$16.66	-5.8%	COM	03969F109
—	UNITY BIOTECHNOLOGY INC	1,680,644	$25.31M	2.4%	$15.06	—	COM	91381U101
—	KEZAR LIFE SCIENCES INC	1,272,198	$22.01M	2.1%	$17.30	—	COM	49372L100
—	FIBROGEN INC	350,000	$21.91M	2.1%	—	—	Call	31572Q908
SGMO	SANGAMO THERAPEUTICS INC	1,509,671	$21.44M	2.0%	$16.61	0.0%	COM	800677106
—	MAGENTA THERAPEUTICS INC	1,538,088	$20.76M	2.0%	$13.50	—	COM	55910K108
—	GILEAD SCIENCES INC	292,600	$20.73M	2.0%	—	—	Call	375558903
—	IMMUNE DESIGN CORP	4,437,600	$20.19M	1.9%	$3.77	—	COM	45252L103
WVE	WAVE LIFE SCIENCES LTD	412,871	$15.79M	1.5%	$30.27	+42.2%	COM	Y95308105
—	SURFACE ONCOLOGY INC	890,808	$14.53M	1.4%	$16.31	—	COM	86877M209
—	EIGER BIOPHARMACEUTICALS INC	1,039,500	$12.68M	1.2%	$12.20	—	COM	28249U105
—	IRONWOOD PHARMACEUTICALS INC	577,600	$11.04M	1.1%	—	—	Call	46333X908
—	ACHILLION PHARMACEUTICALS INC	3,887,407	$11M	1.0%	$3.26	—	COM	00448Q201
—	KADMON HLDGS INC	2,500,000	$9.975M	0.9%	$3.99	—	COM	48283N106
—	ASSEMBLY BIOSCIENCES INC	148,100	$5.807M	0.6%	—	—	Call	045396908
—	DBV TECHNOLOGIES S A	298,100	$5.75M	0.5%	$23.07	—	SPONSORED ADR	23306J101
CRVS	CORVUS PHARMACEUTICALS INC	450,400	$4.945M	0.5%	$11.04	+1.2%	COM	221015100
—	AQUINOX PHARMACEUTICALS INC	1,150,000	$3.048M	0.3%	$2.65	—	COM	03842B101
—	ONCONOVA THERAPEUTICS INC	7,500,000	$3.034M	0.3%	$0.40	—	COM	68232V306
—	ERYTECH PHARMA	153,964	$1.734M	0.2%	$11.26	—	SPONSORED ADR	29604W108
—	APTINYX INC	41,037	$992K	0.1%	$24.17	—	COM	03836N103
INFIQ	INFINITY PHARMACEUTICALS INC	412,000	$787K	0.1%	$2.02	0.0%	COM	45665G303