Location: Boston, MA
CIK: 0001583977 · Show all filings
Period: Q4 2018 (← Previous) (Next →)
Filing Date: Feb 14, 2019
Total Value: $1.232B (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| — | TESARO INC | 1,253,300 | $93.06M | 7.6% | $44.96 | — | Call | 881569107 |
| — | MIRATI THERAPEUTICS INC | 1,751,699 | $74.31M | 6.0% | $19.29 | — | COM | 60468T105 |
| ANAB | ANAPTYSBIO INC | 1,105,557 | $70.52M | 5.7% | $39.24 | +89.5% | COM | 032724106 |
| — | TESARO INC | 900,000 | $66.83M | 5.4% | $44.96 | — | COM | 881569107 |
| APLS | APELLIS PHARMACEUTICALS INC | 4,502,498 | $59.39M | 4.8% | $15.50 | -1.0% | COM | 03753U106 |
| IFRX | INFLARX NV | 1,475,140 | $53.65M | 4.4% | $20.02 | +53.7% | COM | N44821101 |
| ARGX | ARGEN SE | 450,000 | $43.23M | 3.5% | $82.17 | — | SPONSORED ADR | 04016X101 |
| — | PRINCIPIA BIOPHARMA INC | 1,474,362 | $40.38M | 3.3% | $29.22 | — | COM | 74257L108 |
| — | REATA PHARMACEUTICALS INC | 674,251 | $37.83M | 3.1% | $43.48 | — | CL A | 75615P103 |
| — | DICERNA PHARMACEUTICALS INC | 3,481,471 | $37.22M | 3.0% | $9.03 | — | COM | 253031108 |
| — | KEZAR LIFE SCIENCES INC | 1,422,911 | $33.58M | 2.7% | $17.30 | — | COM | 49372L100 |
| — | MYOKARDIA INC | 677,451 | $33.1M | 2.7% | $17.38 | — | COM | 62857M105 |
| — | QUOTIENT LTD | 4,762,772 | $29.15M | 2.4% | $8.95 | — | SHS | G73268107 |
| RCKT | ROCKET PHARMACEUTICALS INC | 1,945,659 | $28.84M | 2.3% | $16.37 | +1.4% | COM | 77313F106 |
| — | BIOHAVEN PHARMACTL HLDG CO L | 650,000 | $24.04M | 2.0% | $32.98 | — | COM | G11196105 |
| — | KINIKSA PHARMACEUTICALS LTD | 831,000 | $23.34M | 1.9% | $16.66 | — | COM CL A | G5269C101 |
| TBPH | THERAVANCE BIOPHARMA INC | 884,916 | $22.64M | 1.8% | $24.80 | +8.8% | COM | G8807B106 |
| — | AVROBIO INC | 1,357,784 | $22.61M | 1.8% | $28.56 | — | COM | 05455M100 |
| ASND | ASCENDIS PHARMA A S | 338,456 | $21.2M | 1.7% | $44.95 | — | SPONSORED ADR | 04351P101 |
| — | BLUEPRINT MEDICINES CORP | 361,351 | $19.48M | 1.6% | $66.58 | — | COM | 09627Y109 |
| — | AXONICS MODULATION TECH INC | 1,285,828 | $19.43M | 1.6% | $15.11 | — | COM | 05465P101 |
| — | G1 THERAPEUTICS INC | 994,287 | $19.04M | 1.5% | $20.28 | — | COM | 3621LQ109 |
| — | ZOGENIX INC | 511,395 | $18.64M | 1.5% | $49.31 | — | COM NEW | 98978L204 |
| ZLAB | ZAI LAB LTD | 787,426 | $18.28M | 1.5% | $22.58 | — | ADR | 98887Q104 |
| — | NEKTAR THERAPEUTICS | 547,000 | $17.98M | 1.5% | $69.99 | — | COM | 640268108 |
| — | SAGE THERAPEUTICS INC | 184,000 | $17.63M | 1.4% | $161.07 | — | Put | 78667J108 |
| — | SAGE THERAPEUTICS INC | 183,732 | $17.6M | 1.4% | $161.07 | — | COM | 78667J108 |
| — | SOLID BIOSCIENCES INC | 652,987 | $17.5M | 1.4% | $7.49 | — | COM | 83422E105 |
| — | TRICIDA INC | 731,621 | $17.25M | 1.4% | $29.90 | — | COM | 89610F101 |
| TWST | TWIST BIOSCIENCE CORP | 706,064 | $16.3M | 1.3% | $22.16 | 0.0% | COM | 90184D100 |
| INCY | INCYTE CORP | 251,335 | $15.98M | 1.3% | $68.44 | -5.1% | COM | 45337C102 |
| NBIX | NEUROCRINE BIOSCIENCES INC | 218,222 | $15.58M | 1.3% | $31.24 | +206.7% | COM | 64125C109 |
| INSP | INSPIRE MED SYS INC | 290,239 | $12.26M | 1.0% | $32.28 | +31.7% | COM | 457730109 |
| — | ARENA PHARMACEUTICALS INC | 300,000 | $11.69M | 0.9% | $42.46 | — | COM NEW | 040047607 |
| SRPT | SAREPTA THERAPEUTICS INC | 90,000 | $9.822M | 0.8% | $125.06 | 0.0% | COM | 803607100 |
| — | AMARIN CORP PLC | 700,000 | $9.527M | 0.8% | $15.51 | — | SPONS ADR NEW | 023111206 |
| — | ZOGENIX INC | 250,000 | $9.115M | 0.7% | $49.31 | — | Call | 98978L204 |
| — | ARRAY BIOPHARMA INC | 580,756 | $8.276M | 0.7% | $6.75 | — | COM | 04269X105 |
| — | NEKTAR THERAPEUTICS | 250,000 | $8.218M | 0.7% | $69.99 | — | Call | 640268108 |
| — | RA PHARMACEUTICALS INC | 441,000 | $8.026M | 0.7% | $18.20 | — | COM | 74933V108 |
| — | ALLAKOS INC | 150,000 | $7.841M | 0.6% | $52.27 | — | COM | 01671P100 |
| KURA | KURA ONCOLOGY INC | 550,000 | $7.722M | 0.6% | $13.25 | 0.0% | COM | 50127T109 |
| — | ORCHARD THERAPEUTICS PLC | 375,000 | $5.899M | 0.5% | $15.73 | — | ADS | 68570P101 |
| — | RUBIUS THERAPEUTICS INC | 360,910 | $5.803M | 0.5% | $24.00 | — | COM | 78116T103 |
| — | EIDOS THERAPEUTICS INC | 385,846 | $5.309M | 0.4% | $19.32 | — | COM | 28249H104 |
| — | CONSTELLATION PHARMACEUTICALS I | 1,271,687 | $5.099M | 0.4% | $6.73 | — | COM | 210373106 |
| SRRK | SCHOLAR ROCK HLDG CORP | 210,078 | $4.825M | 0.4% | $18.88 | +19.8% | COM | 80706P103 |
| REPL | REPLIMUNE GROUP INC | 467,792 | $4.678M | 0.4% | $17.53 | -22.9% | COM | 76029N106 |
| CTMX | CYTOMX THERAPEUTICS INC | 296,712 | $4.48M | 0.4% | $14.84 | 0.0% | COM | 23284F105 |
| — | CONTRAFECT CORP | 2,905,638 | $4.446M | 0.4% | $2.80 | — | COM | 212326102 |
| — | ARSANIS INC | 1,861,702 | $4.319M | 0.4% | $2.32 | — | COM | 042873109 |
| HRTX | HERON THERAPEUTICS INC | 165,682 | $4.298M | 0.3% | $15.72 | +74.9% | COM | 427746102 |
| COLL | COLLEGIUM PHARMACEUTICAL INC | 245,370 | $4.213M | 0.3% | $17.28 | -1.0% | COM | 19459J104 |
| — | MINERVA NEUROSCIENCES INC | 607,903 | $4.097M | 0.3% | $7.26 | — | COM | 603380106 |
| — | Y MABS THERAPEUTICS INC | 194,768 | $3.961M | 0.3% | $26.56 | — | COM | 984241109 |
| ACRS | ACLARIS THERAPEUTICS INC | 478,055 | $3.533M | 0.3% | $19.94 | -48.3% | COM | 00461U105 |
| — | ABEONA THERAPEUTICS INC | 488,534 | $3.488M | 0.3% | $8.20 | — | COM | 00289Y107 |
| — | TRANSLATE BIO INC | 454,550 | $3.409M | 0.3% | $12.65 | — | COM | 89374L104 |
| — | PHASEBIO PHARMACEUTICALS INC | 1,097,926 | $3.393M | 0.3% | $3.09 | — | COM | 717224109 |
| CRSP | CRISPR THERAPEUTICS AG | 100,000 | $2.857M | 0.2% | $34.76 | 0.0% | NAMEN AKT | H17182108 |
| — | AUDENTES THERAPEUTICS INC | 121,797 | $2.597M | 0.2% | $18.38 | — | COM | 05070R104 |
| — | ITERUM THERAPEUTICS PLC | 466,002 | $2.335M | 0.2% | $10.89 | — | SHS | G6333L101 |
| MGTX | MEIRAGTX HOLDGIN PLC | 238,579 | $2.3M | 0.2% | $13.41 | -5.9% | COM | G59665102 |
| SGMO | SANGAMO THERAPEUTICS INC | 194,274 | $2.23M | 0.2% | $6.37 | +94.9% | COM | 800677106 |
| — | ACCELERON PHARMA INC | 48,695 | $2.121M | 0.2% | $32.04 | — | COM | 00434H108 |
| OMER | OMEROS CORP | 181,700 | $2.024M | 0.2% | $16.18 | -13.4% | Call | 682143102 |
| QTRX | QUANTERIX CORP | 54,945 | $1.006M | 0.1% | $19.52 | -8.1% | COM | 74766Q101 |
| — | ARQULE INC | 292,095 | $809K | 0.1% | $5.66 | — | COM | 04269E107 |
| — | OUTLOOK THERAPEUTICS INC | 416,666 | $64,000 | 0.0% | $0.15 | — | *W EXP 02/18/201 | 69012T115 |
| — | CELLECTAR BIOSCIENCES INC | 52,999 | $3,000 | 0.0% | $0.55 | — | *W EXP 08/20/201 | 15117F120 |