Location: New York, NY
CIK: 0001590144 · Show all filings
Period: Q3 2021 (← Previous) (Next →)
Filing Date: Nov 15, 2021
Total Value: $3.286B (99.7% shares, 0.3% debt)
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| — | INVESCO QQQ TR | 850,000 | $304M | 9.3% | — | — | Put | 46090E953 |
| — | SPDR S&P 500 ETF TR | 550,000 | $236M | 7.2% | — | — | Put | 78462F953 |
| — | ISHARES TR | 600,000 | $131M | 4.0% | — | — | Put | 464287955 |
| VRAYQ | VIEWRAY INC | 11,161,088 | $80.47M | 2.4% | $4.12 | +53.1% | COM | 92672L107 |
| ESTA | ESTABLISHMENT LABS HLDGS INC | 1,086,461 | $77.77M | 2.4% | $23.72 | +210.5% | COM | G31249108 |
| — | NANOSTRING TECHNOLOGIES INC | 1,324,165 | $63.57M | 1.9% | $29.66 | — | COM | 63009R109 |
| LIVN | LIVANOVA PLC | 747,472 | $59.19M | 1.8% | $73.99 | +11.1% | SHS | G5509L101 |
| — | INOVALON HLDGS INC | 1,328,700 | $53.53M | 1.6% | — | — | Call | 45781D901 |
| — | ARK ETF TR | 650,000 | $48.57M | 1.5% | — | — | Put | 00214Q952 |
| INSP | INSPIRE MED SYS INC | 204,510 | $47.63M | 1.4% | $52.28 | +299.1% | COM | 457730109 |
| — | ARK ETF TR | 400,000 | $44.21M | 1.3% | — | — | Put | 00214Q954 |
| — | ONCOCYTE CORP | 12,223,953 | $43.52M | 1.3% | $3.67 | — | COM | 68235C107 |
| — | HUMANA INC | 105,000 | $40.86M | 1.2% | — | — | Put | 444859952 |
| — | SPDR SER TR | 325,000 | $40.86M | 1.2% | — | — | Put | 78464A950 |
| — | CUTERA INC | 805,354 | $37.53M | 1.1% | $36.60 | — | COM | 232109108 |
| — | FIRST TR EXCHANGE TRADED FD | 300,000 | $35.71M | 1.1% | — | — | Put | 33734X953 |
| — | AMN HEALTHCARE SVCS INC | 300,000 | $34.42M | 1.0% | — | — | Call | 001744901 |
| — | COMPASS PATHWAYS PLC | 1,131,400 | $33.8M | 1.0% | — | — | Put | 20451W951 |
| ATRC | ATRICURE INC | 479,293 | $33.34M | 1.0% | $39.63 | +94.2% | COM | 04963C209 |
| — | UNITEDHEALTH GROUP INC | 85,000 | $33.21M | 1.0% | — | — | Put | 91324P952 |
| — | ICU MED INC | 140,000 | $32.67M | 1.0% | — | — | Call | 44930G907 |
| ICUI | ICU MED INC | 134,724 | $31.44M | 1.0% | $206.68 | +1.5% | COM | 44930G107 |
| — | ILLUMINA INC | 75,000 | $30.42M | 0.9% | — | — | Put | 452327959 |
| LUNG | PULMONX CORP | 841,764 | $30.29M | 0.9% | $45.67 | -13.8% | COM | 745848101 |
| SEER | SEER INC | 857,306 | $29.6M | 0.9% | $43.03 | -20.0% | COM CL A | 81578P106 |
| — | ALCON AG | 360,000 | $28.97M | 0.9% | — | — | Put | H01301958 |
| — | TELADOC HEALTH INC | 220,000 | $27.9M | 0.8% | — | — | Put | 87918A955 |
| NTRA | NATERA INC | 240,693 | $26.82M | 0.8% | $72.46 | +58.2% | COM | 632307104 |
| — | OUTSET MED INC | 541,192 | $26.76M | 0.8% | $51.32 | — | COM | 690145107 |
| — | UNIVERSAL HLTH SVCS INC | 190,000 | $26.29M | 0.8% | — | — | Put | 913903950 |
| — | DEXCOM INC | 45,000 | $24.61M | 0.7% | — | — | Put | 252131957 |
| MAPS | WM TECHNOLOGY INC | 1,612,498 | $23.38M | 0.7% | $14.46 | 0.0% | COM | 92971A109 |
| — | 10X GENOMICS INC | 160,000 | $23.29M | 0.7% | — | — | Put | 88025U959 |
| — | EXACT SCIENCES CORP | 235,000 | $22.43M | 0.7% | — | — | Put | 30063P955 |
| — | GUARDANT HEALTH INC | 174,000 | $21.75M | 0.7% | — | — | Put | 40131M959 |
| STAA | STAAR SURGICAL CO | 166,193 | $21.36M | 0.7% | $37.56 | +272.6% | COM PAR $0.01 | 852312305 |
| — | STAAR SURGICAL CO | 165,000 | $21.21M | 0.6% | — | — | Put | 852312955 |
| — | BAXTER INTL INC | 250,000 | $20.11M | 0.6% | — | — | Call | 071813909 |
| — | CORTEXYME INC | 209,000 | $19.16M | 0.6% | — | — | Call | 22053A907 |
| — | IDEXX LABS INC | 30,000 | $18.66M | 0.6% | — | — | Put | 45168D954 |
| GKOS | GLAUKOS CORP | 378,638 | $18.24M | 0.6% | $56.87 | -2.5% | COM | 377322102 |
| — | VERTEX PHARMACEUTICALS INC | 100,000 | $18.14M | 0.6% | — | — | Call | 92532F900 |
| — | CUTERA INC | 387,900 | $18.08M | 0.6% | — | — | Call | 232109908 |
| — | ATAI LIFE SCIENCES NV | 1,291,872 | $17.99M | 0.5% | $16.94 | — | SHS | N0731H103 |
| SKIN | THE BEAUTY HEALTH COMPANY | 692,437 | $17.98M | 0.5% | $16.71 | +31.6% | COM CL A | 88331L108 |
| — | PACIFIC BIOSCIENCES CALIF IN | 700,000 | $17.89M | 0.5% | — | — | Put | 69404D958 |
| — | ARENA PHARMACEUTICALS INC | 300,000 | $17.86M | 0.5% | — | — | Call | 040047907 |
| — | AMYRIS INC | 1,275,096 | $17.51M | 0.5% | $14.20 | — | COM NEW | 03236M200 |
| — | INTEGRA LIFESCIENCES HLDGS C | 245,100 | $16.78M | 0.5% | — | — | Put | 457985958 |
| — | COOPER COS INC | 40,000 | $16.53M | 0.5% | $413.30 | — | COM NEW | 216648402 |
| QTRX | QUANTERIX CORP | 326,712 | $16.27M | 0.5% | $49.41 | +4.3% | COM | 74766Q101 |
| — | HYDROFARM HLDGS GROUP INC | 427,285 | $16.17M | 0.5% | $52.37 | — | COM | 44888K209 |
| — | CANO HEALTH INC | 1,275,000 | $16.17M | 0.5% | $12.68 | — | COM CL A | 13781Y103 |
| — | MEDTRONIC PLC | 120,000 | $15.04M | 0.5% | — | — | Call | G5960L903 |
| — | NUVASIVE INC | 250,000 | $14.96M | 0.5% | — | — | Put | 670704955 |
| DXCM | DEXCOM INC | 27,102 | $14.82M | 0.5% | $38.17 | +230.3% | COM | 252131107 |
| — | HOLOGIC INC | 200,000 | $14.76M | 0.4% | — | — | Put | 436440951 |
| OLPX | OLAPLEX HLDGS INC | 600,000 | $14.7M | 0.4% | $24.50 | 0.0% | COM | 679369108 |
| — | TRUPANION INC | 188,200 | $14.62M | 0.4% | — | — | Put | 898202956 |
| — | VEEVA SYS INC | 50,000 | $14.41M | 0.4% | — | — | Put | 922475958 |
| — | METTLER TOLEDO INTERNATIONAL | 10,000 | $13.77M | 0.4% | — | — | Put | 592688955 |
| — | QUOTIENT LTD | 5,859,812 | $13.71M | 0.4% | $4.20 | — | SHS | G73268107 |
| — | APRIA INC | 355,465 | $13.21M | 0.4% | $27.93 | — | COM | 03836A101 |
| — | SOMALOGIC INC | 1,037,645 | $12.86M | 0.4% | $12.39 | — | CLASS A COM | 83444K105 |
| — | INTELLIA THERAPEUTICS INC | 95,700 | $12.84M | 0.4% | — | — | Call | 45826J905 |
| — | CVS HEALTH CORP | 150,000 | $12.73M | 0.4% | — | — | Put | 126650950 |
| — | SPDR SER TR | 100,000 | $12.57M | 0.4% | — | — | Call | 78464A900 |
| — | GLAUKOS CORP | 250,000 | $12.04M | 0.4% | — | — | Call | 377322902 |
| — | CONVEY HLDG PARENT INC | 1,429,946 | $12.01M | 0.4% | $8.40 | — | COM | 21258C108 |
| — | BAUSCH HEALTH COS INC | 430,000 | $11.98M | 0.4% | — | — | Call | 071734907 |
| — | TANDEM DIABETES CARE INC | 100,000 | $11.94M | 0.4% | — | — | Put | 875372953 |
| APYX | APYX MEDICAL CORPORATION | 857,018 | $11.87M | 0.4% | $5.99 | +75.5% | COM | 03837C106 |
| — | ABBOTT LABS | 100,000 | $11.81M | 0.4% | — | — | Put | 002824950 |
| AGL | AGILON HEALTH INC | 447,402 | $11.73M | 0.4% | $34.92 | -2.1% | COM | 00857U107 |
| — | ZOETIS INC | 60,000 | $11.65M | 0.4% | — | — | Put | 98978V953 |
| — | ORTHOPEDIATRICS CORP | 169,600 | $11.11M | 0.3% | — | — | Put | 68752L950 |
| — | ACCELERON PHARMA INC | 64,400 | $11.08M | 0.3% | — | — | Call | 00434H908 |
| CDXS | CODEXIS INC | 476,170 | $11.08M | 0.3% | $17.84 | +32.6% | COM | 192005106 |
| — | DANAHER CORPORATION | 35,000 | $10.65M | 0.3% | — | — | Put | 235851952 |
| — | AMGEN INC | 50,000 | $10.63M | 0.3% | — | — | Call | 031162900 |
| — | GILEAD SCIENCES INC | 150,000 | $10.48M | 0.3% | — | — | Call | 375558903 |
| — | ORTHO CLINICAL DIAGNOSTICS H | 550,000 | $10.16M | 0.3% | $18.48 | — | ORD SHS | G6829J107 |
| PRVA | PRIVIA HEALTH GROUP INC | 418,613 | $9.863M | 0.3% | $36.30 | -3.8% | COM | 74276R102 |
| — | IVERIC BIO INC | 605,800 | $9.838M | 0.3% | — | — | Call | 46583P902 |
| — | SHOCKWAVE MED INC | 47,500 | $9.779M | 0.3% | — | — | Put | 82489T954 |
| — | ABIOMED INC | 30,000 | $9.766M | 0.3% | — | — | Put | 003654950 |
| — | ATAI LIFE SCIENCES NV | 651,500 | $9.636M | 0.3% | — | — | Put | N0731H953 |
| — | SELECT SECTOR SPDR TR | 75,000 | $9.548M | 0.3% | — | — | Put | 81369Y959 |
| CTKB | CYTEK BIOSCIENCES INC | 444,368 | $9.514M | 0.3% | $23.52 | 0.0% | COM | 23285D109 |
| ZBH | ZIMMER BIOMET HOLDINGS INC | 65,000 | $9.513M | 0.3% | $123.42 | +14.8% | COM | 98956P102 |
| — | NEVRO CORP | 80,000 | $9.31M | 0.3% | — | — | Call | 64157F903 |
| TXG | 10X GENOMICS INC | 63,661 | $9.268M | 0.3% | $114.45 | +50.0% | CL A COM | 88025U109 |
| PSNL | PERSONALIS INC | 479,651 | $9.228M | 0.3% | $23.01 | -9.1% | COM | 71535D106 |
| AMN | AMN HEALTHCARE SVCS INC | 80,000 | $9.18M | 0.3% | $106.04 | 0.0% | COM | 001744101 |
| HAE | HAEMONETICS CORP MASS | 130,000 | $9.177M | 0.3% | $63.10 | 0.0% | COM | 405024100 |
| STXS | STEREOTAXIS INC | 1,678,638 | $9.031M | 0.3% | $5.27 | +43.1% | COM NEW | 85916J409 |
| — | FULGENT GENETICS INC | 100,000 | $8.995M | 0.3% | — | — | Put | 359664959 |
| — | CYTOKINETICS INC | 25,000 | $8.849M | 0.3% | $3.52 | — | NOTE 4.000%11/1 | 23282WAA8 |
| — | OLINK HLDG AB | 362,746 | $8.797M | 0.3% | $33.69 | — | SPONSORED ADS | 680710100 |
| ADPT | ADAPTIVE BIOTECHNOLOGIES COR | 255,916 | $8.699M | 0.3% | $40.99 | -11.8% | COM | 00650F109 |
| — | GINKGO BIOWORKS HOLDINGS INC | 750,000 | $8.693M | 0.3% | $11.59 | — | CL A SHS | 37611X100 |
| PACB | PACIFIC BIOSCIENCES CALIF IN | 340,143 | $8.691M | 0.3% | $5.76 | +414.6% | COM | 69404D108 |
| LNTH | LANTHEUS HLDGS INC | 336,926 | $8.652M | 0.3% | $22.95 | +13.8% | COM | 516544103 |
| NEO | NEOGENOMICS INC | 177,778 | $8.576M | 0.3% | $46.29 | 0.0% | COM NEW | 64049M209 |
| TKNO | ALPHA TEKNOVA INC | 344,041 | $8.563M | 0.3% | $25.30 | -15.4% | COM | 02080L102 |
| — | APELLIS PHARMACEUTICALS INC | 259,100 | $8.54M | 0.3% | — | — | Call | 03753U906 |
| EVH | EVOLENT HEALTH INC | 275,000 | $8.525M | 0.3% | $24.01 | 0.0% | CL A | 30050B101 |
| — | WEST PHARMACEUTICAL SVSC INC | 20,000 | $8.491M | 0.3% | — | — | Put | 955306955 |
| GHRS | GH RESEARCH PLC | 380,045 | $8.384M | 0.3% | $20.43 | -0.3% | ORDINARY SHARES | G3855L106 |
| — | BIOGEN INC | 29,400 | $8.32M | 0.3% | — | — | Call | 09062X903 |
| GH | GUARDANT HEALTH INC | 64,023 | $8.004M | 0.2% | $96.26 | +23.4% | COM | 40131M109 |
| PEN | PENUMBRA INC | 30,000 | $7.995M | 0.2% | $268.79 | 0.0% | COM | 70975L107 |
| TELA | TELA BIO INC | 580,515 | $7.93M | 0.2% | $14.10 | -1.1% | COM | 872381108 |
| — | LIVANOVA PLC | 100,000 | $7.919M | 0.2% | — | — | Call | G5509L901 |
| SOPH | SOPHIA GENETICS SA | 450,010 | $7.889M | 0.2% | $17.59 | 0.0% | ORDINARY SHARES | H82027105 |
| MDXG | MIMEDX GROUP INC | 1,275,389 | $7.729M | 0.2% | $7.60 | +48.4% | COM | 602496101 |
| — | LUCIRA HEALTH INC | 1,001,942 | $7.615M | 0.2% | $7.22 | — | COM | 54948U105 |
| IRTC | IRHYTHM TECHNOLOGIES INC | 130,000 | $7.613M | 0.2% | $79.24 | -33.1% | COM | 450056106 |
| — | TELEFLEX INCORPORATED | 20,000 | $7.531M | 0.2% | — | — | Put | 879369956 |
| — | NOVOCURE LTD | 64,100 | $7.446M | 0.2% | — | — | Put | G6674U958 |
| — | VANECK ETF TRUST | 100,000 | $7.282M | 0.2% | — | — | Put | 92189F952 |
| — | MEDPACE HLDGS INC | 37,300 | $7.06M | 0.2% | — | — | Put | 58506Q959 |
| — | WALGREENS BOOTS ALLIANCE INC | 150,000 | $7.058M | 0.2% | — | — | Put | 931427958 |
| — | EVOLENT HEALTH INC | 221,300 | $6.86M | 0.2% | — | — | Call | 30050B901 |
| — | LEMAITRE VASCULAR INC | 126,800 | $6.732M | 0.2% | — | — | Put | 525558951 |
| — | KONINKLIJKE PHILIPS N V | 150,000 | $6.666M | 0.2% | — | — | Put | 500472953 |
| SDGR | SCHRODINGER INC | 121,231 | $6.629M | 0.2% | $72.45 | -11.7% | COM | 80810D103 |
| — | R1 RCM INC | 300,000 | $6.603M | 0.2% | $11.63 | — | COM | 749397105 |
| NYXH | NYXOAH S A | 225,214 | $6.542M | 0.2% | $31.50 | 0.0% | SHS | B6S7WD106 |
| MRK | MERCK & CO INC | 85,000 | $6.384M | 0.2% | $66.14 | 0.0% | COM | 58933Y105 |
| — | IMMUNOGEN INC | 1,097,500 | $6.223M | 0.2% | — | — | Call | 45253H901 |
| RPID | RAPID MICRO BIOSYSTEMS INC | 332,136 | $6.135M | 0.2% | $20.66 | 0.0% | CLASS A COM | 75340L104 |
| PRCT | PROCEPT BIOROBOTICS CORP | 160,000 | $6.104M | 0.2% | $38.38 | 0.0% | COM | 74276L105 |
| BVS | BIOVENTUS INC | 429,129 | $6.076M | 0.2% | $14.24 | +8.0% | COM CL A | 09075A108 |
| — | NEKTAR THERAPEUTICS | 337,600 | $6.063M | 0.2% | — | — | Call | 640268908 |
| — | QUANTERIX CORP | 120,000 | $5.975M | 0.2% | — | — | Call | 74766Q901 |
| — | ARENA PHARMACEUTICALS INC | 100,000 | $5.955M | 0.2% | — | — | Put | 040047957 |
| MASS | 908 DEVICES INC | 180,888 | $5.882M | 0.2% | $54.78 | -38.0% | COM | 65443P102 |
| — | THERMO FISHER SCIENTIFIC INC | 10,000 | $5.713M | 0.2% | — | — | Put | 883556952 |
| NTLA | INTELLIA THERAPEUTICS INC | 42,059 | $5.642M | 0.2% | $68.37 | +121.5% | COM | 45826J105 |
| — | MISONIX INC | 218,100 | $5.518M | 0.2% | $10.64 | — | COM | 604871103 |
| VRTX | VERTEX PHARMACEUTICALS INC | 30,000 | $5.442M | 0.2% | $195.24 | 0.0% | COM | 92532F100 |
| — | INVACARE CORP | 1,137,028 | $5.412M | 0.2% | $8.13 | — | COM | 461203101 |
| — | ARYA SCIENCES ACQU CORP IV | 526,217 | $5.288M | 0.2% | $10.47 | — | CL A | G31659108 |
| — | CHEMOCENTRYX INC | 300,000 | $5.13M | 0.2% | — | — | Put | 16383L956 |
| — | RESEARCH ALLIANCE CORP II | 511,480 | $5.038M | 0.2% | $10.25 | — | COM CL A | 760873109 |
| — | HAEMONETICS CORP MASS | 70,000 | $4.941M | 0.2% | — | — | Call | 405024900 |
| — | LYRA THERAPEUTICS INC | 533,417 | $4.867M | 0.1% | $8.03 | — | COM | 55234L105 |
| MIST | MILESTONE PHARMACEUTICALS IN | 850,312 | $4.855M | 0.1% | $6.30 | -10.5% | COM | 59935V107 |
| — | OWENS & MINOR INC NEW | 150,000 | $4.694M | 0.1% | — | — | Put | 690732952 |
| RCEL | AVITA MEDICAL INC | 252,246 | $4.47M | 0.1% | $23.25 | -18.9% | COM | 05380C102 |
| — | COMPASS PATHWAYS PLC | 148,700 | $4.442M | 0.1% | — | — | Call | 20451W901 |
| — | AURINIA PHARMACEUTICALS INC | 200,000 | $4.426M | 0.1% | — | — | Call | 05156V902 |
| — | CODEX DNA INC | 393,180 | $4.376M | 0.1% | $22.00 | — | COM | 192003101 |
| TPB | TURNING PT BRANDS INC | 91,449 | $4.367M | 0.1% | $39.48 | +21.4% | COM | 90041L105 |
| DH | DEFINITIVE HEALTHCARE CORP | 100,000 | $4.283M | 0.1% | $44.39 | 0.0% | CLASS A COM | 24477E103 |
| — | CUREVAC N V | 76,700 | $4.189M | 0.1% | — | — | Put | N2451R955 |
| CLDX | CELLDEX THERAPEUTICS INC NEW | 77,285 | $4.173M | 0.1% | $22.96 | +104.4% | COM NEW | 15117B202 |
| — | ORGANOGENESIS HLDGS INC | 284,500 | $4.051M | 0.1% | — | — | Put | 68621F952 |
| — | NEKTAR THERAPEUTICS | 219,540 | $3.943M | 0.1% | $17.96 | — | COM | 640268108 |
| — | MARAVAI LIFESCIENCES HLDGS I | 77,500 | $3.804M | 0.1% | — | — | Put | 56600D957 |
| MRVI | MARAVAI LIFESCIENCES HLDGS I | 77,500 | $3.804M | 0.1% | $48.78 | 0.0% | COM CL A | 56600D107 |
| — | CORTEXYME INC | 41,200 | $3.776M | 0.1% | — | — | Put | 22053A957 |
| — | IMMUNOGEN INC | 650,700 | $3.689M | 0.1% | — | — | Put | 45253H951 |
| — | REPLIGEN CORP | 12,500 | $3.612M | 0.1% | — | — | Put | 759916959 |
| — | VIEWRAY INC | 500,000 | $3.605M | 0.1% | — | — | Call | 92672L907 |
| CRVS | CORVUS PHARMACEUTICALS INC | 734,268 | $3.554M | 0.1% | $2.96 | 0.0% | COM | 221015100 |
| — | DECIPHERA PHARMACEUTICALS IN | 99,700 | $3.388M | 0.1% | — | — | Call | 24344T901 |
| — | STRYVE FOODS INC | 575,000 | $3.076M | 0.1% | $5.35 | — | CLASS A COM | 863685103 |
| — | MANNKIND CORP | 700,000 | $3.045M | 0.1% | — | — | Put | 56400P956 |
| AZN | ASTRAZENECA PLC | 50,000 | $3.003M | 0.1% | $60.06 | — | SPONSORED ADR | 046353108 |
| — | FATE THERAPEUTICS INC | 50,000 | $2.964M | 0.1% | — | — | Put | 31189P952 |
| — | IRHYTHM TECHNOLOGIES INC | 50,000 | $2.928M | 0.1% | — | — | Call | 450056906 |
| — | QUOTIENT LTD | 1,231,900 | $2.883M | 0.1% | — | — | Call | G73268907 |
| BHC | BAUSCH HEALTH COS INC | 100,000 | $2.785M | 0.1% | $28.36 | 0.0% | COM | 071734107 |
| — | BIONANO GENOMICS INC | 500,000 | $2.75M | 0.1% | $3.08 | — | COM | 09075F107 |
| ARQT | ARCUTIS BIOTHERAPEUTICS INC | 112,324 | $2.683M | 0.1% | $31.23 | -27.0% | COM | 03969K108 |
| — | MIRATI THERAPEUTICS INC | 15,000 | $2.654M | 0.1% | $181.22 | — | COM | 60468T105 |
| — | DYNAMICS SPECIAL PURPOSE COR | 255,700 | $2.542M | 0.1% | $9.94 | — | CLASS A COM | 268010105 |
| — | CANO HEALTH INC | 200,000 | $2.536M | 0.1% | — | — | Call | 13781Y903 |
| BEAM | BEAM THERAPEUTICS INC | 24,573 | $2.138M | 0.1% | $79.68 | +26.1% | COM | 07373V105 |
| — | FRONTIER ACQUISITION CORP | 213,023 | $2.103M | 0.1% | $9.93 | — | UNIT 03/01/2026 | G36826116 |
| — | MEDAVAIL HOLDINGS INC | 714,120 | $2.085M | 0.1% | $14.25 | — | COM | 58406B103 |
| — | INCYTE CORP | 30,000 | $2.063M | 0.1% | — | — | Put | 45337C952 |
| — | BELLUS HEALTH INC NEW | 334,805 | $2.056M | 0.1% | $6.14 | — | COM NEW | 07987C204 |
| — | EDITAS MEDICINE INC | 50,000 | $2.054M | 0.1% | — | — | Put | 28106W953 |
| — | EDITAS MEDICINE INC | 48,900 | $2.009M | 0.1% | — | — | Call | 28106W903 |
| — | GEMINI THERAPEUTICS INC | 494,400 | $1.997M | 0.1% | $4.04 | — | COM | 36870G105 |
| — | DA32 LIFE SCNCE TEC ACQSTN C | 200,000 | $1.966M | 0.1% | $9.83 | — | CLASS A COM | 23312M106 |
| — | INTRA-CELLULAR THERAPIES INC | 52,213 | $1.947M | 0.1% | $37.29 | — | COM | 46116X101 |
| — | IMMUNOGEN INC | 343,048 | $1.945M | 0.1% | $6.84 | — | COM | 45253H101 |
| — | AVADEL PHARMACEUTICALS PLC | 192,000 | $1.882M | 0.1% | — | — | Call | 05337M904 |
| — | AMICUS THERAPEUTICS INC | 196,800 | $1.879M | 0.1% | — | — | Call | 03152W909 |
| IMCR | IMMUNOCORE HLDGS PLC | 50,000 | $1.854M | 0.1% | $37.08 | — | ADS | 45258D105 |
| CGEM | CULLINAN ONCOLOGY INC | 81,418 | $1.838M | 0.1% | $39.61 | -32.5% | COM | 230031106 |
| NUVB | NUVATION BIO INC | 178,403 | $1.773M | 0.1% | $9.06 | 0.0% | COM CL A | 67080N101 |
| — | THORNE HEALTHTECH INC | 200,000 | $1.73M | 0.1% | $8.65 | — | COM | 885260109 |
| — | DECIPHERA PHARMACEUTICALS IN | 50,000 | $1.699M | 0.1% | $33.98 | — | COM | 24344T101 |
| — | SIERRA ONCOLOGY INC | 73,633 | $1.614M | 0.0% | $15.41 | — | COM NEW | 82640U404 |
| UTHR | UNITED THERAPEUTICS CORP DEL | 8,587 | $1.585M | 0.0% | $196.97 | 0.0% | COM | 91307C102 |
| — | PRIVETERRA ACQUISITION CORP | 159,468 | $1.584M | 0.0% | $9.94 | — | UNIT 99/99/9999 | 74275N201 |
| KURA | KURA ONCOLOGY INC | 83,266 | $1.56M | 0.0% | $25.81 | -27.0% | COM | 50127T109 |
| — | CATALYST BIOSCIENCES INC | 372,582 | $1.531M | 0.0% | $4.11 | — | COM NEW | 14888D208 |
| — | FIELD TRIP HEALTH LTD | 305,700 | $1.403M | 0.0% | — | — | Call | 31656R902 |
| — | RENOVACOR INC | 152,079 | $1.376M | 0.0% | $9.05 | — | COM | 75989E106 |
| — | ADAPTIVE BIOTECHNOLOGIES COR | 40,000 | $1.36M | 0.0% | — | — | Call | 00650F909 |
| — | REPARE THERAPEUTICS INC | 50,000 | $1.312M | 0.0% | — | — | Call | 760273902 |
| TVTX | TRAVERE THERAPEUTICS INC | 53,790 | $1.304M | 0.0% | $27.63 | -33.5% | COM | 89422G107 |
| — | CYCLERION THERAPEUTICS INC | 422,311 | $1.296M | 0.0% | $3.90 | — | COM | 23255M105 |
| — | ARENA PHARMACEUTICALS INC | 20,000 | $1.191M | 0.0% | $59.55 | — | COM NEW | 040047607 |
| — | NEVRO CORP | 10,000 | $1.164M | 0.0% | $165.80 | — | COM | 64157F103 |
| — | ABG ACQUISITION CORP I | 119,228 | $1.161M | 0.0% | $9.89 | — | CL A SHS | G00496102 |
| GOSS | GOSSAMER BIO INC | 90,077 | $1.132M | 0.0% | $10.08 | -8.7% | COM | 38341P102 |
| — | LOGICBIO THERAPEUTICS INC | 245,492 | $1.124M | 0.0% | $7.63 | — | COM | 54142F102 |
| ABOS | ACUMEN PHARMACEUTICALS INC | 75,000 | $1.115M | 0.0% | $16.64 | 0.0% | COM | 00509G209 |
| TNGX | TANGO THERAPEUTICS INC | 84,762 | $1.096M | 0.0% | $11.99 | 0.0% | COM | 87583X109 |
| — | HEALTH SCIENCES ACQ CORP 2 | 106,302 | $1.051M | 0.0% | $11.02 | — | ORD SHS | G4411D109 |
| PHAT | PHATHOM PHARMACEUTICALS INC | 32,575 | $1.046M | 0.0% | $40.59 | -18.1% | COM | 71722W107 |
| CRBU | CARIBOU BIOSCIENCES INC | 43,639 | $1.042M | 0.0% | $24.45 | 0.0% | COM | 142038108 |
| — | ARYA SCIENCES ACQUISITN CORP | 100,000 | $988K | 0.0% | $9.88 | — | CLASS A ORD SHS | G31658100 |
| — | VINCERX PHARMA INC | 59,809 | $967K | 0.0% | $18.48 | — | COM NEW | 92731L106 |
| VRDN | VIRIDIAN THERAPEUTICS INC | 58,096 | $956K | 0.0% | $14.67 | 0.0% | COM | 92790C104 |
| FHTX | FOGHORN THERAPEUTICS INC | 68,095 | $949K | 0.0% | $11.07 | 0.0% | COM | 344174107 |
| — | CLEARSIDE BIOMEDICAL INC | 156,500 | $939K | 0.0% | — | — | Call | 185063904 |
| — | CHINOOK THERAPEUTICS INC | 72,698 | $928K | 0.0% | $14.13 | — | COM | 16961L106 |
| — | AVEO PHARMACEUTICALS INC | 147,574 | $912K | 0.0% | $6.45 | — | COM NEW | 053588307 |
| NAUT | NAUTILUS BIOTECHNOLOGY INC | 148,300 | $911K | 0.0% | $10.83 | -26.4% | COM | 63909J108 |
| — | NGM BIOPHARMACEUTICALS INC | 43,317 | $911K | 0.0% | $21.03 | — | COM | 62921N105 |
| CCCC | C4 THERAPEUTICS INC | 20,000 | $894K | 0.0% | $42.82 | 0.0% | COM STK | 12529R107 |
| — | GREENLANE HLDGS INC | 362,568 | $859K | 0.0% | $5.76 | — | CL A | 395330103 |
| — | POSEIDA THERAPEUTICS INC | 114,343 | $834K | 0.0% | $9.55 | — | COM | 73730P108 |
| — | CARDIOVASCULAR SYS INC DEL | 25,000 | $821K | 0.0% | — | — | Put | 141619956 |
| — | SILVER SPIKE ACQUISITN CORP | 77,505 | $777K | 0.0% | $9.95 | — | UNIT 02/26/2026 | G8201H121 |
| — | XENON PHARMACEUTICALS INC | 50,000 | $764K | 0.0% | — | — | Put | 98420N955 |
| XENE | XENON PHARMACEUTICALS INC | 50,000 | $764K | 0.0% | $17.38 | 0.0% | COM | 98420N105 |
| — | THERAVANCE BIOPHARMA INC | 100,000 | $740K | 0.0% | — | — | Call | G8807B906 |
| TBPH | THERAVANCE BIOPHARMA INC | 100,000 | $740K | 0.0% | $14.89 | -24.9% | COM | G8807B106 |
| — | BELLUS HEALTH INC NEW | 117,300 | $720K | 0.0% | — | — | Put | 07987C954 |
| — | SOMALOGIC INC | 207,527 | $716K | 0.0% | $3.45 | — | *W EXP 03/01/202 | 83444K113 |
| — | CHEMOCENTRYX INC | 40,600 | $694K | 0.0% | — | — | Call | 16383L906 |
| — | UNIVERSE PHARMACEUTICALS INC | 267,959 | $662K | 0.0% | $2.47 | — | SHS | G9442G104 |
| — | KRYSTAL BIOTECH INC | 12,300 | $642K | 0.0% | — | — | Put | 501147952 |
| — | REPARE THERAPEUTICS INC | 22,143 | $581K | 0.0% | $30.69 | — | COM | 760273102 |
| — | ONCONOVA THERAPEUTICS INC | 150,000 | $575K | 0.0% | $3.83 | — | COM NEW | 68232V801 |
| — | CYCLACEL PHARMACEUTICALS INC | 105,141 | $554K | 0.0% | $7.81 | — | COM | 23254L603 |
| — | GOSSAMER BIO INC | 5,000 | $522K | 0.0% | $2.03 | — | NOTE 5.000% 6/0 | 38341PAA0 |
| — | MIND MEDICINE MINDMED INC | 222,200 | $518K | 0.0% | — | — | Call | 60255C909 |
| — | IVERIC BIO INC | 31,765 | $516K | 0.0% | $6.30 | — | COM | 46583P102 |
| IPHA | INNATE PHARMA S A | 82,509 | $509K | 0.0% | $6.17 | — | SPONSORED ADS | 45781K204 |
| CTMX | CYTOMX THERAPEUTICS INC | 99,371 | $506K | 0.0% | $7.92 | -32.4% | COM | 23284F105 |
| — | DECIPHERA PHARMACEUTICALS IN | 13,600 | $462K | 0.0% | — | — | Put | 24344T951 |
| — | KADMON HLDGS INC | 52,300 | $456K | 0.0% | $8.72 | — | COM | 48283N106 |
| — | TRICIDA INC | 95,022 | $441K | 0.0% | $4.45 | — | COM | 89610F101 |
| — | ALTIMMUNE INC | 39,000 | $441K | 0.0% | — | — | Put | 02155H950 |
| ABUS | ARBUTUS BIOPHARMA CORP | 100,000 | $429K | 0.0% | $3.33 | 0.0% | COM | 03879J100 |
| EDIT | EDITAS MEDICINE INC | 10,000 | $411K | 0.0% | $54.79 | 0.0% | COM | 28106W103 |
| KALV | KALVISTA PHARMACEUTICALS INC | 21,948 | $383K | 0.0% | $25.73 | -21.2% | COM | 483497103 |
| — | FIBROGEN INC | 34,869 | $356K | 0.0% | $10.21 | — | COM | 31572Q808 |
| — | BRAINSTORM CELL THERAPEUTICS | 106,834 | $353K | 0.0% | $3.30 | — | COM NEW | 10501E201 |
| — | IONIS PHARMACEUTICALS INC | 10,500 | $352K | 0.0% | — | — | Put | 462222950 |
| TALKW | TALKSPACE INC | 440,455 | $339K | 0.0% | $1.35 | — | *W EXP 06/21/202 | 87427V111 |
| — | IVERIC BIO INC | 20,200 | $328K | 0.0% | — | — | Put | 46583P952 |
| — | BRAINSTORM CELL THERAPEUTICS | 97,400 | $321K | 0.0% | — | — | Call | 10501E901 |
| BYSI | BEYONDSPRING INC | 20,100 | $317K | 0.0% | $17.97 | 0.0% | SHS | G10830100 |
| — | MONTES ARCHIMEDES ACQUISITIO | 205,400 | $306K | 0.0% | $1.49 | — | *W EXP 99/99/999 | 612657114 |
| — | BEYONDSPRING INC | 16,900 | $266K | 0.0% | — | — | Put | G10830950 |
| — | SENSEI BIOTHERAPEUTICS INC | 22,603 | $238K | 0.0% | $13.97 | — | COM | 81728A108 |
| ACIU | AC IMMUNE SA | 35,000 | $235K | 0.0% | $7.16 | 0.0% | SHS | H00263105 |
| MAPSW | WM TECHNOLOGY INC | 50,000 | $216K | 0.0% | $6.36 | — | *W EXP 06/16/202 | 92971A117 |
| — | TUATARA CAPITAL ACQUISITN CO | 20,000 | $200K | 0.0% | $10.00 | — | UNIT 99/99/9999 | G9118J127 |
| SVRA | SAVARA INC | 97,461 | $134K | 0.0% | $1.71 | -21.1% | COM | 805111101 |
| — | LEAP THERAPEUTICS INC | 25,000 | $100K | 0.0% | $4.00 | — | COM | 52187K101 |
| — | PHASEBIO PHARMACEUTICALS INC | 27,944 | $87,000 | 0.0% | $3.11 | — | COM | 717224109 |
| — | RENOVACOR INC | 150,632 | $85,000 | 0.0% | $0.56 | — | *W EXP 99/99/999 | 75989E114 |