Location: New York, NY
CIK: 0001590144 · Show all filings
Period: Q1 2022 (← Previous) (Next →)
Filing Date: May 16, 2022
Total Value: $3.084B (99.7% shares, 0.3% debt)
| Ticker | Issuer | Shares | Value | % | Share Price | Est. Cost/Share | Unrealized @ Report Date | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|---|
| — | ISHARES TR | 1,050,000 | $216M | 7.0% | $205.27 | — | — | Put | 464287955 |
| — | SPDR S&P 500 ETF TR | 450,000 | $203M | 6.6% | $451.64 | — | — | Put | 78462F953 |
| — | SPDR SER TR | 1,391,800 | $125M | 4.1% | $89.88 | — | — | Put | 78464A950 |
| — | INVESCO QQQ TR | 300,000 | $109M | 3.5% | $362.54 | — | — | Put | 46090E953 |
| — | ARK ETF TR | 2,250,000 | $103M | 3.4% | $45.93 | — | — | Put | 00214Q952 |
| — | ISHARES TR | 1,400,000 | $85.34M | 2.8% | $60.96 | — | — | Put | 464288950 |
| — | CUTERA INC | 1,074,151 | $74.12M | 2.4% | $69.00 | $37.91 | — | COM | 232109108 |
| — | BIOGEN INC | 348,900 | $73.48M | 2.4% | $210.60 | — | — | Call | 09062X903 |
| ESTA | ESTABLISHMENT LABS HLDGS INC | 962,494 | $64.86M | 2.1% | $67.39 * | $25.35 | +130.7% | COM | G31249108 |
| — | ESTABLISHMENT LABS HLDGS INC | 945,200 | $63.7M | 2.1% | $67.39 | — | — | Call | G31249908 |
| — | ARK ETF TR | 900,000 | $59.66M | 1.9% | $66.29 | — | — | Put | 00214Q954 |
| VRAYQ | VIEWRAY INC | 13,561,808 | $53.16M | 1.7% | $3.92 * | $4.53 | -6.1% | COM | 92672L107 |
| INSP | INSPIRE MED SYS INC | 203,442 | $52.22M | 1.7% | $256.69 * | $61.17 | +273.6% | COM | 457730109 |
| — | GLAUKOS CORP | 868,100 | $50.19M | 1.6% | $57.82 | — | — | Call | 377322902 |
| — | MEDTRONIC PLC | 400,000 | $44.38M | 1.4% | $110.95 | — | — | Call | G5960L903 |
| — | CUTERA INC | 635,000 | $43.81M | 1.4% | $69.00 | — | — | Call | 232109908 |
| — | NANOSTRING TECHNOLOGIES INC | 1,220,332 | $42.41M | 1.4% | $34.75 | $29.81 | — | COM | 63009R109 |
| — | MEDTRONIC PLC | 360,000 | $39.94M | 1.3% | $110.95 | — | — | Put | G5960L953 |
| — | ISHARES TR | 275,700 | $35.92M | 1.2% | $130.30 | — | — | Put | 464287956 |
| — | LIVANOVA PLC | 381,600 | $31.23M | 1.0% | $81.83 | — | — | Call | G5509L901 |
| — | BAXTER INTL INC | 400,000 | $31.02M | 1.0% | $77.54 | — | — | Put | 071813959 |
| BIIB | BIOGEN INC | 147,135 | $30.99M | 1.0% | $210.60 * | $217.46 | 0.0% | COM | 09062X103 |
| — | BECTON DICKINSON & CO | 112,500 | $29.93M | 1.0% | $266.00 | — | — | Put | 075887959 |
| — | ZIMMER BIOMET HOLDINGS INC | 225,000 | $28.78M | 0.9% | $127.90 | — | — | Call | 98956P902 |
| LIVN | LIVANOVA PLC | 347,498 | $28.44M | 0.9% | $81.83 * | $73.99 | +5.1% | SHS | G5509L101 |
| — | JOHNSON & JOHNSON | 150,000 | $26.59M | 0.9% | $177.23 | — | — | Put | 478160954 |
| — | QUEST DIAGNOSTICS INC | 184,200 | $25.21M | 0.8% | $136.86 | — | — | Put | 74834L950 |
| — | ABBOTT LABS | 195,000 | $23.08M | 0.7% | $118.36 | — | — | Put | 002824950 |
| — | FIRST TR EXCHANGE TRADED FD | 200,000 | $22.93M | 0.7% | $114.66 | — | — | Put | 33734X953 |
| — | INTUITIVE SURGICAL INC | 75,500 | $22.78M | 0.7% | $301.68 | — | — | Call | 46120E902 |
| — | ILLUMINA INC | 65,000 | $22.71M | 0.7% | $349.40 | — | — | Call | 452327909 |
| ATRC | ATRICURE INC | 336,615 | $22.11M | 0.7% | $65.67 | $39.63 | +63.5% | COM | 04963C209 |
| VRTX | VERTEX PHARMACEUTICALS INC | 84,057 | $21.94M | 0.7% | $260.97 * | $224.99 | +5.5% | COM | 92532F100 |
| — | 10X GENOMICS INC | 284,400 | $21.63M | 0.7% | $76.07 | — | — | Put | 88025U959 |
| — | OUTSET MED INC | 474,901 | $21.56M | 0.7% | $45.40 | $51.05 | — | COM | 690145107 |
| — | TRUPANION INC | 225,000 | $20.05M | 0.7% | $89.12 | — | — | Put | 898202956 |
| — | STRYKER CORPORATION | 75,000 | $20.05M | 0.7% | $267.35 | — | — | Put | 863667951 |
| — | SOMALOGIC INC | 2,475,815 | $19.86M | 0.6% | $8.02 | $11.95 | — | CLASS A COM | 83444K105 |
| — | SEER INC | 1,300,000 | $19.81M | 0.6% | $15.24 | — | — | Call | 81578P906 |
| — | GUARDANT HEALTH INC | 275,000 | $18.22M | 0.6% | $66.24 | — | — | Call | 40131M909 |
| — | ONCOCYTE CORP | 12,223,953 | $18.21M | 0.6% | $1.49 | $3.67 | — | COM | 68235C107 |
| — | DENTSPLY SIRONA INC | 368,000 | $18.11M | 0.6% | $49.22 | — | — | Put | 24906P959 |
| — | SPDR SER TR | 199,200 | $17.9M | 0.6% | $89.88 | — | — | Call | 78464A900 |
| — | BOSTON SCIENTIFIC CORP | 400,000 | $17.72M | 0.6% | $44.29 | — | — | Call | 101137907 |
| — | WATERS CORP | 54,000 | $16.76M | 0.5% | $310.39 | — | — | Put | 941848953 |
| — | ABBVIE INC | 100,000 | $16.21M | 0.5% | $162.11 | — | — | Put | 00287Y959 |
| — | VAREX IMAGING CORP | 750,000 | $15.97M | 0.5% | $21.29 | — | — | Put | 92214X956 |
| STAA | STAAR SURGICAL CO | 196,074 | $15.67M | 0.5% | $79.91 * | $44.17 | +68.6% | COM PAR $0.01 | 852312305 |
| — | SAREPTA THERAPEUTICS INC | 200,000 | $15.62M | 0.5% | $78.12 | — | — | Call | 803607900 |
| — | COOPER COS INC | 37,300 | $15.58M | 0.5% | $417.59 | — | — | Call | 216648902 |
| CCCC | C4 THERAPEUTICS INC | 624,860 | $15.16M | 0.5% | $24.26 | $25.10 | -3.3% | COM STK | 12529R107 |
| — | METTLER TOLEDO INTERNATIONAL | 11,000 | $15.11M | 0.5% | $1373.18 | — | — | Put | 592688955 |
| LUNG | PULMONX CORP | 589,722 | $14.63M | 0.5% | $24.81 * | $41.98 | -38.5% | COM | 745848101 |
| — | IVERIC BIO INC | 865,144 | $14.56M | 0.5% | $16.83 | $16.35 | — | COM | 46583P102 |
| — | RESMED INC | 57,500 | $13.94M | 0.5% | $242.50 | — | — | Put | 761152957 |
| — | PULMONX CORP | 554,700 | $13.76M | 0.4% | $24.81 | — | — | Call | 745848901 |
| — | STAAR SURGICAL CO | 170,000 | $13.59M | 0.4% | $79.91 | — | — | Put | 852312955 |
| BMRN | BIOMARIN PHARMACEUTICAL INC | 175,356 | $13.52M | 0.4% | $77.10 * | $82.55 | +1.4% | COM | 09061G101 |
| — | CELLDEX THERAPEUTICS INC NEW | 396,600 | $13.51M | 0.4% | $34.06 | — | — | Call | 15117B902 |
| — | IRHYTHM TECHNOLOGIES INC | 85,000 | $13.38M | 0.4% | $157.47 | — | — | Call | 450056906 |
| — | ICU MED INC | 59,600 | $13.27M | 0.4% | $222.63 | — | — | Call | 44930G907 |
| — | CONMED CORP | 89,000 | $13.22M | 0.4% | $148.55 | — | — | Put | 207410951 |
| — | ISHARES TR | 100,000 | $13.03M | 0.4% | $130.30 | — | — | Call | 464287906 |
| ICUI | ICU MED INC | 57,700 | $12.85M | 0.4% | $222.63 | $206.68 | +8.4% | COM | 44930G107 |
| — | ENVISTA HOLDINGS CORPORATION | 260,000 | $12.66M | 0.4% | $48.71 | — | — | Put | 29415F954 |
| — | CVS HEALTH CORP | 123,700 | $12.52M | 0.4% | $101.21 | — | — | Put | 126650950 |
| LNTH | LANTHEUS HLDGS INC | 222,238 | $12.29M | 0.4% | $55.31 * | $22.95 | +63.5% | COM | 516544103 |
| — | PACIFIC BIOSCIENCES CALIF IN | 1,350,000 | $12.29M | 0.4% | $9.10 | — | — | Put | 69404D958 |
| — | QUOTIENT LTD | 10,157,408 | $12.19M | 0.4% | $1.20 | $3.31 | — | SHS | G73268107 |
| — | HEALTHEQUITY INC | 180,000 | $12.14M | 0.4% | $67.44 | — | — | Call | 42226A907 |
| — | MOLSON COORS BEVERAGE CO | 218,300 | $11.65M | 0.4% | $53.38 | — | — | Put | 60871R959 |
| — | CONVEY HEALTH SOLUTIONS HLDG | 1,720,752 | $11.25M | 0.4% | $6.54 | $8.13 | — | COM | 21258C108 |
| — | THERMO FISHER SCIENTIFIC INC | 19,000 | $11.22M | 0.4% | $590.63 | — | — | Put | 883556952 |
| — | NATERA INC | 275,000 | $11.19M | 0.4% | $40.68 | — | — | Call | 632307904 |
| — | AVANTOR INC | 325,000 | $10.99M | 0.4% | $33.82 | — | — | Put | 05352A950 |
| TECH | BIO-TECHNE CORP | 25,000 | $10.83M | 0.4% | $433.04 * | $101.38 | 0.0% | COM | 09073M104 |
| — | AMYRIS INC | 2,461,436 | $10.73M | 0.3% | $4.36 | $4.36 | — | COM NEW | 03236M200 |
| — | OLINK HLDG AB | 590,000 | $10.42M | 0.3% | $17.66 | — | — | Call | 680710900 |
| — | APELLIS PHARMACEUTICALS INC | 200,000 | $10.16M | 0.3% | $50.81 | — | — | Call | 03753U906 |
| — | QUANTERIX CORP | 344,600 | $10.06M | 0.3% | $29.19 | — | — | Call | 74766Q901 |
| — | AGILENT TECHNOLOGIES INC | 75,000 | $9.925M | 0.3% | $132.33 | — | — | Put | 00846U951 |
| — | VIEWRAY INC | 2,500,000 | $9.8M | 0.3% | $3.92 | — | — | Call | 92672L907 |
| CDXS | CODEXIS INC | 465,902 | $9.607M | 0.3% | $20.62 | $17.84 | +16.1% | COM | 192005106 |
| — | SELECT SECTOR SPDR TR | 125,000 | $9.486M | 0.3% | $75.89 | — | — | Put | 81369Y958 |
| — | EXACT SCIENCES CORP | 135,000 | $9.439M | 0.3% | $69.92 | — | — | Call | 30063P905 |
| — | CYTOKINETICS INC | 25,000 | $9.149M | 0.3% | $365.96 | $3.52 | — | NOTE 4.000%11/1 | 23282WAA8 |
| — | INSPIRE MED SYS INC | 35,000 | $8.984M | 0.3% | $256.69 | — | — | Call | 457730909 |
| — | IVERIC BIO INC | 529,600 | $8.913M | 0.3% | $16.83 | — | — | Call | 46583P902 |
| — | THE BEAUTY HEALTH COMPANY | 524,100 | $8.847M | 0.3% | $16.88 | — | — | Call | 88331L908 |
| — | MODERNA INC | 50,000 | $8.613M | 0.3% | $172.26 | — | — | Call | 60770K907 |
| — | GUARDANT HEALTH INC | 130,000 | $8.611M | 0.3% | $66.24 | — | — | Put | 40131M959 |
| — | TENET HEALTHCARE CORP | 95,000 | $8.166M | 0.3% | $85.96 | — | — | Call | 88033G907 |
| — | ALNYLAM PHARMACEUTICALS INC | 50,000 | $8.165M | 0.3% | $163.30 | — | — | Put | 02043Q957 |
| — | PRIVIA HEALTH GROUP INC | 300,000 | $8.019M | 0.3% | $26.73 | — | — | Call | 74276R902 |
| — | INTEGRA LIFESCIENCES HLDGS C | 123,900 | $7.962M | 0.3% | $64.26 | — | — | Put | 457985958 |
| BVS | BIOVENTUS INC | 555,910 | $7.838M | 0.3% | $14.10 * | $14.24 | -6.0% | COM CL A | 09075A108 |
| IMUX | IMMUNIC INC | 683,287 | $7.721M | 0.3% | $11.30 * | $11.58 | 0.0% | COM | 4525EP101 |
| NTLA | INTELLIA THERAPEUTICS INC | 104,073 | $7.563M | 0.2% | $72.67 * | $82.74 | +2.4% | COM | 45826J105 |
| — | WALGREENS BOOTS ALLIANCE INC | 160,000 | $7.163M | 0.2% | $44.77 | — | — | Call | 931427908 |
| — | AZENTA INC | 84,500 | $7.003M | 0.2% | $82.88 | — | — | Put | 114340952 |
| — | EXACT SCIENCES CORP | 100,000 | $6.992M | 0.2% | $69.92 | — | — | Put | 30063P955 |
| — | LEMAITRE VASCULAR INC | 148,200 | $6.887M | 0.2% | $46.47 | — | — | Put | 525558951 |
| — | STAAR SURGICAL CO | 85,000 | $6.792M | 0.2% | $79.91 | — | — | Call | 852312905 |
| TELA | TELA BIO INC | 567,420 | $6.599M | 0.2% | $11.63 * | $14.10 | -14.1% | COM | 872381108 |
| — | ATAI LIFE SCIENCES NV | 1,278,105 | $6.506M | 0.2% | $5.09 | $10.22 | — | SHS | N0731H103 |
| EVH | EVOLENT HEALTH INC | 200,000 | $6.46M | 0.2% | $32.30 * | $26.18 | 0.0% | CL A | 30050B101 |
| PRVA | PRIVIA HEALTH GROUP INC | 240,200 | $6.421M | 0.2% | $26.73 * | $35.36 | -33.2% | COM | 74276R102 |
| APYX | APYX MEDICAL CORPORATION | 982,683 | $6.417M | 0.2% | $6.53 * | $6.54 | +50.5% | COM | 03837C106 |
| SOPH | SOPHIA GENETICS SA | 829,930 | $6.415M | 0.2% | $7.73 * | $11.23 | 0.0% | ORDINARY SHARES | H82027105 |
| MIST | MILESTONE PHARMACEUTICALS IN | 987,411 | $6.339M | 0.2% | $6.42 * | $6.27 | -0.3% | COM | 59935V107 |
| — | SCHRODINGER INC | 185,000 | $6.312M | 0.2% | $34.12 | — | — | Call | 80810D903 |
| — | GINKGO BIOWORKS HOLDINGS INC | 1,500,000 | $6.045M | 0.2% | $4.03 | — | — | Put | 37611X950 |
| — | GILEAD SCIENCES INC | 100,000 | $5.945M | 0.2% | $59.45 | — | — | Put | 375558953 |
| — | BEAM THERAPEUTICS INC | 100,000 | $5.73M | 0.2% | $57.30 | — | — | Put | 07373V955 |
| RCEL | AVITA MEDICAL INC | 674,316 | $5.718M | 0.2% | $8.48 * | $9.22 | 0.0% | COM | 05380C102 |
| MASS | 908 DEVICES INC | 296,288 | $5.632M | 0.2% | $19.01 * | $44.08 | -61.0% | COM | 65443P102 |
| STXS | STEREOTAXIS INC | 1,479,292 | $5.518M | 0.2% | $3.73 * | $5.27 | -10.4% | COM NEW | 85916J409 |
| — | COOPER COS INC | 13,000 | $5.429M | 0.2% | $417.62 | $417.62 | — | COM NEW | 216648402 |
| — | SCIENCE 37 HOLDINGS INC | 1,006,400 | $5.384M | 0.2% | $5.35 | $5.35 | — | COM | 808644108 |
| — | ZTS | 28,000 | $5.281M | 0.2% | $188.61 | — | — | Put | 98978V953 |
| — | NOVOCURE LTD | 62,700 | $5.195M | 0.2% | $82.85 | — | — | Put | G6674U958 |
| — | APELLIS PHARMACEUTICALS INC | 100,000 | $5.081M | 0.2% | $50.81 | — | — | Put | 03753U956 |
| — | R1 RCM INC | 188,455 | $5.043M | 0.2% | $26.76 | $26.76 | — | COM | 749397105 |
| — | HCA HEALTHCARE INC | 20,000 | $5.012M | 0.2% | $250.60 | — | — | Put | 40412C951 |
| — | MEDPACE HLDGS INC | 30,000 | $4.908M | 0.2% | $163.60 | — | — | Put | 58506Q959 |
| — | C4 THERAPEUTICS INC | 200,000 | $4.852M | 0.2% | $24.26 | — | — | Call | 12529R907 |
| — | ACADIA PHARMACEUTICALS INC | 200,000 | $4.844M | 0.2% | $24.22 | — | — | Call | 004225908 |
| — | ATHIRA PHARMA INC | 339,468 | $4.583M | 0.1% | $13.50 | $13.03 | — | COM | 04746L104 |
| CTKB | CYTEK BIOSCIENCES INC | 424,577 | $4.577M | 0.1% | $10.78 * | $23.52 | -42.6% | COM | 23285D109 |
| GH | GUARDANT HEALTH INC | 68,375 | $4.529M | 0.1% | $66.24 * | $98.94 | -30.8% | COM | 40131M109 |
| CLDX | CELLDEX THERAPEUTICS INC NEW | 132,571 | $4.515M | 0.1% | $34.06 * | $31.49 | +1.5% | COM NEW | 15117B202 |
| — | UNIVERSAL HLTH SVCS INC | 30,000 | $4.349M | 0.1% | $144.97 | — | — | Put | 913903950 |
| NYXH | NYXOAH S A | 221,949 | $4.304M | 0.1% | $19.39 * | $31.50 | -35.7% | SHS | B6S7WD106 |
| — | SONENDO INC | 1,023,424 | $4.104M | 0.1% | $4.01 | $5.51 | — | COM | 835431107 |
| — | GREENLIGHT BIOSCIENCS HLDS P | 400,000 | $3.852M | 0.1% | $9.63 | $9.63 | — | COMMON STOCK | 39536G105 |
| — | AVITA MEDICAL INC | 450,000 | $3.816M | 0.1% | $8.48 | — | — | Call | 05380C902 |
| GHRS | GH RESEARCH PLC | 208,527 | $3.814M | 0.1% | $18.29 * | $20.43 | -13.5% | ORDINARY SHARES | G3855L106 |
| ARQT | ARCUTIS BIOTHERAPEUTICS INC | 189,363 | $3.647M | 0.1% | $19.26 * | $25.82 | -34.5% | COM | 03969K108 |
| — | TELADOC HEALTH INC | 50,000 | $3.607M | 0.1% | $72.14 | — | — | Put | 87918A955 |
| TKNO | ALPHA TEKNOVA INC | 251,112 | $3.468M | 0.1% | $13.81 * | $25.30 | -37.8% | COM | 02080L102 |
| — | IMMUNIC INC | 300,000 | $3.39M | 0.1% | $11.30 | — | — | Put | 4525EP951 |
| TGTX | TG THERAPEUTICS INC | 328,187 | $3.121M | 0.1% | $9.51 * | $11.57 | 0.0% | COM | 88322Q108 |
| — | INMODE LTD | 84,000 | $3.1M | 0.1% | $36.90 | — | — | Put | M5425M953 |
| LAB | FLUIDIGM CORP DEL | 850,000 | $3.052M | 0.1% | $3.59 * | $3.45 | 0.0% | COM | 34385P108 |
| — | INTEGER HLDGS CORP | 37,500 | $3.021M | 0.1% | $80.56 | — | — | Put | 45826H959 |
| — | ICAD INC | 672,989 | $3.002M | 0.1% | $4.46 | $4.46 | — | COM NEW | 44934S206 |
| UTHR | UNITED THERAPEUTICS CORP DEL | 16,561 | $2.971M | 0.1% | $179.40 * | $194.62 | -2.1% | COM | 91307C102 |
| — | ORTHOPEDIATRICS CORP | 55,000 | $2.969M | 0.1% | $53.98 | — | — | Put | 68752L950 |
| TVTX | TRAVERE THERAPEUTICS INC | 110,225 | $2.84M | 0.1% | $25.77 * | $27.90 | -4.8% | COM | 89422G107 |
| — | BELLUS HEALTH INC NEW | 390,097 | $2.684M | 0.1% | $6.88 | $6.40 | — | COM NEW | 07987C204 |
| — | IGM BIOSCIENCES INC | 100,000 | $2.673M | 0.1% | $26.73 | — | — | Call | 449585908 |
| — | APOLLO ENDOSURGERY INC | 427,057 | $2.584M | 0.1% | $6.05 | $8.14 | — | COM | 03767D108 |
| — | ANAVEX LIFE SCIENCES CORP | 200,000 | $2.462M | 0.1% | $12.31 | — | — | Call | 032797900 |
| — | LUCIRA HEALTH INC | 687,213 | $2.453M | 0.1% | $3.57 | $7.41 | — | COM | 54948U105 |
| — | NEKTAR THERAPEUTICS | 434,900 | $2.344M | 0.1% | $5.39 | — | — | Call | 640268908 |
| — | NANO X IMAGING LTD | 200,000 | $2.168M | 0.1% | $10.84 | — | — | Put | M70700955 |
| PTON | PELOTON INTERACTIVE INC | 80,000 | $2.114M | 0.1% | $26.43 * | $28.67 | 0.0% | CL A COM | 70614W100 |
| — | LYRA THERAPEUTICS INC | 520,544 | $2.093M | 0.1% | $4.02 | $8.03 | — | COM | 55234L105 |
| ADPT | ADAPTIVE BIOTECHNOLOGIES COR | 150,000 | $2.082M | 0.1% | $13.88 * | $15.72 | 0.0% | COM | 00650F109 |
| SRPT | SAREPTA THERAPEUTICS INC | 25,850 | $2.019M | 0.1% | $78.10 | $76.58 | 0.0% | COM | 803607100 |
| — | ALNYLAM PHARMACEUTICALS INC | 12,300 | $2.008M | 0.1% | $163.25 | — | — | Call | 02043Q907 |
| AZN | ASTRAZENECA PLC | 30,000 | $1.99M | 0.1% | $66.33 | $66.33 | — | SPONSORED ADR | 046353108 |
| VRDN | VIRIDIAN THERAPEUTICS INC | 105,460 | $1.95M | 0.1% | $18.49 * | $16.43 | +16.9% | COM | 92790C104 |
| LQDA | LIQUIDIA CORPORATION | 251,604 | $1.807M | 0.1% | $7.18 * | $5.82 | +8.1% | COM NEW | 53635D202 |
| — | AURINIA PHARMACEUTICALS INC | 143,000 | $1.77M | 0.1% | $12.38 | — | — | Call | 05156V902 |
| — | UNITY BIOTECHNOLOGY INC | 1,578,140 | $1.768M | 0.1% | $1.12 | $1.12 | — | COM | 91381U101 |
| — | MERUS N V | 66,547 | $1.76M | 0.1% | $26.45 | $31.16 | — | COM | N5749R100 |
| SDGR | SCHRODINGER INC | 50,000 | $1.706M | 0.1% | $34.12 * | $30.38 | 0.0% | COM | 80810D103 |
| TXG | 10X GENOMICS INC | 22,257 | $1.693M | 0.1% | $76.07 * | $114.45 | -23.6% | CL A COM | 88025U109 |
| — | RUBIUS THERAPEUTICS INC | 300,000 | $1.653M | 0.1% | $5.51 | — | — | Call | 78116T903 |
| — | DA32 LIFE SCNCE TEC ACQSTN C | 164,834 | $1.601M | 0.1% | $9.71 | $9.83 | — | CLASS A COM | 23312M106 |
| — | ARCUS BIOSCIENCES INC | 50,000 | $1.578M | 0.1% | $31.56 | — | — | Call | 03969F909 |
| PTGX | PROTAGONIST THERAPEUTICS INC | 65,371 | $1.548M | 0.1% | $23.68 * | $28.17 | 0.0% | COM | 74366E102 |
| — | TRICIDA INC | 180,816 | $1.486M | 0.0% | $8.22 | $8.22 | — | COM | 89610F101 |
| — | CHINOOK THERAPEUTICS INC | 85,236 | $1.394M | 0.0% | $16.35 | $14.55 | — | COM | 16961L106 |
| PHAT | PHATHOM PHARMACEUTICALS INC | 102,328 | $1.393M | 0.0% | $13.61 * | $29.00 | -44.3% | COM | 71722W107 |
| MAPS | WM TECHNOLOGY INC | 178,000 | $1.392M | 0.0% | $7.82 * | $5.67 | 0.0% | COM | 92971A109 |
| — | UNIVERSE PHARMACEUTICALS INC | 1,079,437 | $1.366M | 0.0% | $1.27 | $1.84 | — | SHS | G9442G104 |
| — | ADICET BIO INC | 66,626 | $1.331M | 0.0% | $19.98 | $17.49 | — | COM | 007002108 |
| — | BIOHAVEN PHARMACTL HLDG CO L | 10,985 | $1.302M | 0.0% | $118.53 | $137.80 | — | COM | G11196105 |
| — | CORTEXYME INC | 200,000 | $1.238M | 0.0% | $6.19 | — | — | Call | 22053A907 |
| AGL | AGILON HEALTH INC | 45,000 | $1.141M | 0.0% | $25.36 * | $34.92 | -41.0% | COM | 00857U107 |
| — | CARDINAL HEALTH INC | 20,000 | $1.134M | 0.0% | $56.70 | — | — | Put | 14149Y958 |
| NAUT | NAUTILUS BIOTECHNOLOGY INC | 244,698 | $1.062M | 0.0% | $4.34 * | $8.06 | -49.1% | COM | 63909J108 |
| — | HEALTH SCIENCES ACQ CORP 2 | 104,026 | $1.031M | 0.0% | $9.91 | $11.02 | — | ORD SHS | G4411D109 |
| — | GLOBAL BLOOD THERAPEUTICS IN | 29,454 | $1.02M | 0.0% | $34.63 | $34.63 | — | COM | 37890U108 |
| — | GERON CORP | 702,600 | $956K | 0.0% | $1.36 | — | — | Call | 374163903 |
| — | UNITY BIOTECHNOLOGY INC | 783,800 | $878K | 0.0% | $1.12 | — | — | Call | 91381U901 |
| — | CYCLERION THERAPEUTICS INC | 776,497 | $862K | 0.0% | $1.11 | $2.91 | — | COM | 23255M105 |
| — | AGENUS INC | 348,800 | $858K | 0.0% | $2.46 | — | — | Call | 00847G905 |
| CRVS | CORVUS PHARMACEUTICALS INC | 495,484 | $813K | 0.0% | $1.64 * | $2.96 | -38.2% | COM | 221015100 |
| GOSS | GOSSAMER BIO INC | 87,929 | $763K | 0.0% | $8.68 * | $10.08 | -4.4% | COM | 38341P102 |
| — | CUE HEALTH INC | 114,500 | $739K | 0.0% | $6.45 | — | — | Put | 229790950 |
| — | MEDAVAIL HOLDINGS INC | 714,120 | $693K | 0.0% | $0.97 | $14.25 | — | COM | 58406B103 |
| — | GEMINI THERAPEUTICS INC | 496,120 | $690K | 0.0% | $1.39 | $4.04 | — | COM | 36870G105 |
| TNGX | TANGO THERAPEUTICS INC | 82,727 | $627K | 0.0% | $7.58 * | $11.99 | -27.7% | COM | 87583X109 |
| — | RENOVACOR INC | 145,390 | $616K | 0.0% | $4.24 | $9.05 | — | COM | 75989E106 |
| — | THERAPEUTICSMD INC | 1,619,080 | $615K | 0.0% | $0.38 | $0.38 | — | COM | 88338N107 |
| KALV | KALVISTA PHARMACEUTICALS INC | 41,393 | $610K | 0.0% | $14.74 * | $21.16 | -32.1% | COM | 483497103 |
| — | QUOTIENT LTD | 500,000 | $600K | 0.0% | $1.20 | — | — | Call | G73268907 |
| — | IVERIC BIO INC | 34,000 | $572K | 0.0% | $16.82 | — | — | Put | 46583P952 |
| ABOS | ACUMEN PHARMACEUTICALS INC | 145,195 | $568K | 0.0% | $3.91 * | $13.18 | -58.7% | COM | 00509G209 |
| — | TRAVERE THERAPEUTICS INC | 5,000 | $532K | 0.0% | $106.40 | $106.40 | — | NOTE 2.250% 3/0 | 89422GAA5 |
| — | CULLINAN ONCOLOGY INC | 45,900 | $481K | 0.0% | $10.48 | — | — | Put | 230031956 |
| XENE | XENON PHARMACEUTICALS INC | 15,002 | $459K | 0.0% | $30.60 * | $17.38 | +72.3% | COM | 98420N105 |
| PYXS | PYXIS ONCOLOGY INC | 113,362 | $458K | 0.0% | $4.04 * | $11.45 | -36.2% | COMMON STOCK | 747324101 |
| — | VINCERX PHARMA INC | 108,459 | $434K | 0.0% | $4.00 | $14.77 | — | COM NEW | 92731L106 |
| — | SOMALOGIC INC | 204,401 | $413K | 0.0% | $2.02 | $3.45 | — | *W EXP 08/31/202 | 83444K113 |
| RLMD | RELMADA THERAPEUTICS INC | 14,885 | $402K | 0.0% | $27.01 * | $22.24 | -7.0% | COM | 75955J402 |
| — | GOSSAMER BIO INC | 5,000 | $402K | 0.0% | $80.40 | $2.03 | — | NOTE 5.000% 6/0 | 38341PAA0 |
| — | IMARA INC | 196,635 | $370K | 0.0% | $1.88 | $2.25 | — | COM | 45249V107 |
| — | PROQR THRAPEUTICS N V | 277,900 | $252K | 0.0% | $0.91 | — | — | Call | N71542909 |
| — | CARDIOVASCULAR SYS INC DEL | 10,911 | $247K | 0.0% | $22.64 | $22.64 | — | COM | 141619106 |
| — | CYCLACEL PHARMACEUTICALS INC | 77,568 | $237K | 0.0% | $3.06 | $7.81 | — | COM | 23254L603 |
| — | TUATARA CAPITAL ACQUISITN CO | 20,000 | $198K | 0.0% | $9.90 | $10.00 | — | UNIT 99/99/9999 | G9118J127 |
| — | ROIVANT SCIENCES LTD | 199,648 | $176K | 0.0% | $0.88 | $2.05 | — | *W EXP 09/30/202 | G76279119 |
| ACHV | ACHIEVE LIFE SCIENCES INC | 17,325 | $131K | 0.0% | $7.56 | $7.83 | -4.9% | COM | 004468500 |
| AMLX | AMYLYX PHARMACEUTICALS INC | 10,000 | $129K | 0.0% | $12.90 * | $22.45 | 0.0% | COM | 03237H101 |
| SVRA | SAVARA INC | 95,014 | $124K | 0.0% | $1.31 * | $1.71 | -29.6% | COM | 805111101 |
| — | METACRINE INC | 198,230 | $121K | 0.0% | $0.61 | $0.67 | — | COM | 59101E103 |
| MAPSW | WM TECHNOLOGY INC | 50,000 | $110K | 0.0% | $2.20 | $6.36 | — | *W EXP 06/16/202 | 92971A117 |
| TALKW | TALKSPACE INC | 427,194 | $103K | 0.0% | $0.24 | $1.35 | — | *W EXP 06/21/202 | 87427V111 |
| — | GLYCOMIMETICS INC | 87,678 | $100K | 0.0% | $1.14 | $1.14 | — | COM | 38000Q102 |
| WVE | WAVE LIFE SCIENCES LTD | 40,886 | $82,000 | 0.0% | $2.01 * | $4.15 | -41.0% | SHS | Y95308105 |
| — | RENOVACOR INC | 150,632 | $41,000 | 0.0% | $0.27 | $0.56 | — | *W EXP 99/99/999 | 75989E114 |
| EFTRW | EFFECTOR THERAPEUTICS INC | 100,541 | $35,000 | 0.0% | $0.35 | $0.88 | — | *W EXP 12/31/202 | 28202V116 |